Dxt 20mg Tablet
10 Tablet(s) in StripWe do not sell this product
Made by
RELIANCE FORMULATION PVT LTD
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Duloxetine(20.0 Mg) |
| Uses | Major depressive disorders in adults only, Moderate to severe stress urinary incontinence in women, Neuropathic pain associated with diabetic peripheral neuropathy |
| Therapy | Anti-depressant |
| Side effects | Nausea, Vomiting, Headache, Dry mouth, Loss of appetite, Increased irritability, Diarrhoea, Tremors, Delayed ejaculation/erectile dysfunction, Loss of sexual drive, Sleepiness, Dizziness, Bleeding, Abdominal pain, Urinary hesitation, Retention |
Assurance
available
Regulated
Medical Description
DXT 20mg Tablet is a prescription medication. It contains Duloxetine as its active ingredient. It is used to manage depression in adults, stress urinary incontinence in women, neuropathic pain, fibromyalgia, chronic musculoskeletal pain and generalised anxiety disorder.
Anxiety and depression are mental health disorders. These disorders can lead to feeling excessively sad, angry and unmotivated. Pain is an unpleasant feeling caused by the formation of certain chemicals in the body in response to an injury, tissue damage or disease. Stress urinary incontinence is urine leakage during moments of physical activity that increase abdominal pressure, such as coughing, sneezing, laughing, or exercise. These disorders may lead to a decrease in quality of life.
Duloxetine helps manage these disorders by enhancing the effects of certain chemicals in the brain called norepinephrine and serotonin. This, in turn, will reduce the symptoms of these conditions. It is important to only take this medication on prescription by a doctor, at the exact dose and for the entire duration prescribed.
Uses
- As per CDSCO, DXT 20 mg is primarily used to manage the following conditions:
- Major depressive disorders in adults
- Moderate to severe stress urinary incontinence in women
- Management of neuropathic pain associated with diabetic peripheral neuropathy
Contraindications
- DXT 20 mg is contraindicated in the following cases:
- In patients below the age of 18
- In patients who suffer from unstable epilepsy
- In patients with a very low sodium level
- In patients with kidney, liver or heart problems
- In patients with glaucoma
- In patients with bleeding disorders
- In patients with a known hypersensitivity to Duloxetine
Side effects
- Nausea
- Vomiting
- Headache
- Dry mouth
- Loss of appetite
- Increased irritability
- Sexual dysfunction
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You suffer from any health problems; inform your physician before starting this medication. If you have ever had a seizure, manic episodes, or have bipolar disorder, your physician may need to modify the dose prescribed to you accordingly.
- You develop suicidal thoughts.
- You are on any medications. Based on this information, your doctor may choose to prescribe you a different drug or modify the dose prescribed to you.
Directions for Use
- Take this medication at fixed times every day.
- Take this medication with or without food.
- Swallow the tablet whole; do not split, crush, or chew.
- Take this medication at the recommended dose. Do not alter the dose, as this may lead to undesirable side effects.
- Take this medication for the entire duration prescribed by the doctor. Abruptly stopping this medication can lead to side effects such as increased irritability, difficulty sleeping, nausea or anxiety.
Storage and disposal
Store this medication in a cool and dry place. Avoid exposure to direct sunlight. Dispose of medicine after the date of expiry.
Dosage
Overdose
An overdose of this medication can lead to many serious side effects. The most common symptoms are nausea, vomiting and diarrhoea, convulsions, dizziness, somnolence, which may progress to coma and respiratory difficulties. Immediately seek medical care at a tertiary centre in case of an overdose.
Missed a Dose
In case of a missed dose, take it as soon as you remember. However, if it is time for your next scheduled dose, skip the missed dose and continue with your regular scheduled dose. Do not double the dose of this medication.
Mode of Action
How Does It Work?
There are a number of chemicals present in the body known as neurotransmitters. These transmitters include two chemicals known as serotonin and norepinephrine. These transmitters play an important role in mood disorders, pain and bladder function.
The pharmacological component of DXT 20mg Tablet is a drug called Duloxetine. Duloxetine is serotonin- and norepinephrine-reuptake inhibitor, which enhances the available serotonin and norepinephrine activity in the body. This, in turn, will reduce the symptoms of depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain and stress incontinence.
Interactions
Interactions with other medicines
- Co-administration of Tranylcypromine or other monoamine oxidase (MAO) inhibitors is contraindicated as the risk or severity of adverse effects can increase. Taking them within 14 days of treatment is also contraindicated.
- Co-administration with Tizanidine, Thioridazine, Aldosterone, Pimozide is contraindicated as the severity of the adverse effects of the drugs increases when combined.
- Co-administration with Tapentadol, or other agents that increase serotonin levels is not recommended, as it may increase the central nervous system depressant effects of the drug. This can precipitate a dangerous side effect called Serotonin Syndrome.
- Co-administration with other benzodiazepines and strong painkillers like Tramadol is not recommended as it can enhance its actions.
- Co-administration with warfarin, NSAIDs (Non-steroidal anti-inflammatory drugs), aspirin, or other drugs affecting coagulation (aka, blood thinners) is not recommended. This may lead to an increased risk of bleeding.
- The metabolism of certain drugs may get decreased when administered with Duloxetine. This may lead to dangerous side effects. Co-administration of these drugs, including Carbamazepine, Abacavir, etc., is not recommended.
Interactions with food items
- It is recommended to avoid caffeine-containing substances such as tea, coffee, etc., while on this medication. This is because caffeine causes anxiety and may reduce the effectiveness of this medication.
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:DXT
Vendor Details
Fulfillment Information: Dxt 20 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Duloxetine [Internet]. Ncbi.nlm.nih.gov. [cited 1 March 2022] -
- Dhaliwal J, Spurling B, Molla M. Duloxetine [Internet]. Ncbi.nlm.nih.gov. [cited 1 March 2022] -
- CDSCO [Internet]. Cdscoonline.gov.in. 2005 [cited 1 March 2022] -
- Duloxetine: Uses, Interactions, Mechanism of Action | DrugBank Online [Internet]. Go.drugbank.com. [cited 1 March 2022] -
- [Internet]. Accessdata.fda.gov. [cited 1 March 2022]. -
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
