Nexpro Rd 40mg Capsule
Nexpro Rd 40mg Capsule

Nexpro Rd 40mg Capsule

10 Capsule(s) in Strip
MRP 154.45
15% OFF
Inclusive of all taxes
10 Brand Options Available
Save Upto 8% more
Certified by Doctors
15 days return policyRead More
All the Products are packed and stored Safely
Check more medicines with composition
Domperidone(30.0 Mg) + Esomeprazole(40.0 Mg)
Therapeutic classification

Medical Description

Nexpro RD 40 capsule is used to treat stomach reflux disease in which acid from the stomach flows back to the food pipe and results in heartburn, belching, nausea and chest pain. Nexpro RD 40 capsule ...
Read more

Uses of Nexpro Rd 40mg Capsule

Nexpro RD 40 capsule is used in adults to treat gastroesophageal reflux disease (GERD).

Contraindications of Nexpro Rd 40mg Capsule

  • If you are allergic to Esomeprazole or Domperidone or any other ingredients of Nexpro RD 40 capsule.
  • If you are on any medicine and you have been warned that it might affect the contraction of the heart muscle.
  • If you have an obstruction or perforations in the intestine.
  • If you have any bleeding problem in the digestive tract.
  • If your liver or kidneys are not functioning properly.
  • If you have a heart-related disorder such as heart failure, heart rhythm problems and electrolyte imbalance.
  • If you have a tumour of the pituitary gland (Prolactin pituitary tumours).
  • If you are taking anti-HIV medicines such as Nelfinavir, antibiotics like Clarithromycin, Ketoconazole (antifungal), Verapamil (used to control high blood pressure & chest pain).

Side effects of Nexpro Rd 40mg Capsule

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Bloating
  • Loose motion
  • Weakness
  • Drowsiness
  • Spinning of head
  • Skin rash & itching

Precautions and Warnings of Nexpro Rd 40mg Capsule



Can I take Nexpro RD 40 capsule during pregnancy?
Nexpro RD 40 mg capsule is not recommended when pregnant as there is limited information about its safety for pregnant women. Please consult your doctor before using it.

Breast Feeding

Can I take Nexpro RD 40 capsule while breastfeeding?
Components of Nexpro RD 40 mg capsule might pass into the breast milk in small amounts. It is better to consult your doctor if you are breastfeeding. After assessing the benefits over the risks, your doctor might change the medicine, ask you to stop breastfeeding or closely monitor the baby.


Can I drive if I have consumed Nexpro RD 40 mg capsule?
Nexpro RD 40 mg capsule can make you feel dizzy and drowsy. Avoid driving if you do not feel well or are unable to be alert.


Can I consume alcohol with Nexpro RD 40 mg capsule?
You should avoid consuming alcohol while on treatment with Nexpro RD 40 mg capsules. Alcohol is known to increase acidity and can make your condition worse.

Other General Warnings

Talk to your doctor if
  • You have any liver or kidney-related diseases.
  • You are experiencing stomach pain, indigestion, weight loss, difficulty in swallowing, throwing out food or blood after taking this capsule.
  • You had fractures or have a bone-related disorder such as osteoporosis or taking steroids.
  • You have a heart-related disorder and you often experience symptoms like palpitations, difficulty in breathing and unconsciousness.
  • You are supposed to take capsules for long-term treatment (more than three months). Your blood magnesium levels may decrease. Hence your doctor may prescribe regular tests for the same.
  • You develop skin eruptions especially in the sun-exposed area after taking this medicine.
  • You have a vitamin B12 deficiency as this medicine can reduce the absorption of vitamin B12 after long-term use.
  • Taking Nexpro RD 40 capsule for more than one year may increase the chances of developing bone fractures.
  • Nexpro RD 40 capsule may lead to a slightly increased risk of bacterial infections due to Salmonella and Campylobacter.
  • This medicine is not recommended for patients below 18 years of age.

Mode of Action of Nexpro Rd 40mg Capsule

How Does It Work?

  • Nexpro RD 40 mg capsule is a combination of two components - Esomeprazole and Domperidone and it works via combined action of these components.
  • Esomeprazole belongs to the class of medicines called proton pump inhibitors. The lining of the stomach secretes acid by certain processes that involve the intake of ions via proton pumps in the cells...
    Read more
  • Domperidone acts by increasing the motility of the stomach and intestines so that acid does not reflux back into the food pipe.

Directions for Use of Nexpro Rd 40mg Capsule

  • Take Nexpro RD 40 capsules at least one hour before meals.
  • You should take this capsule preferably in the morning or as prescribed by a doctor.

Interactions of Nexpro Rd 40mg Capsule

Interactions with other medicines

  • Since Nexpro RD 40 mg capsule contains a combination of two components, any interactions with these two components when taken alone may occur with this combination.
  • Nexpro RD 40 capsule should not be taken along with anti-HIV medicines such as Nelfinavir, muscle relaxants such as Amiodarone, antibiotics like Clarithromycin, antifungals like Ketoconazole and antih...
    Read more
  • This capsule should also not be taken along with medicines used to treat heart problems (Quinidine, Sotalol), medicines used for psychiatric illness (Haloperidol, Citalopram), antifungals (Pentamidine...
    Read more
  • Concomitant use of this capsule along with medicines used to treat psychiatric illness (Diazepam), used to treat fits (Phenytoin) is not recommended as it may increase the side effects of this capsule...
    Read more
  • Digoxin which is used to treat heart failure may lead to toxicity when taken with this capsule.
  • Blood-thinners such as Warfarin if taken along with this medicine can increase the chances of bleeding.
  • Other medicines like Rifampicin, Methotrexate, Tacrolimus, Voriconazole, Cilostazol, Clopidogrel, Azithromycin, St John's wort, etc should be used cautiously.

Interactions with food items

Nexpro RD 40 capsule should preferably be taken on an empty stomach at least 1 hour before meals to enhance effectiveness.

Storage and disposal of Nexpro Rd 40mg Capsule

  • Store Nexpro RD 40 capsules below 25°C in a clean and dry place.
  • Keep it out of the reach and sight of children and pets.

Dosage of Nexpro Rd 40mg Capsule


The symptoms of an overdose of Nexpro RD 40 capsules include nausea, vomiting, indigestion, diarrhoea, constipation, weakness, confusion, agitation, anxiety, fits, altered consciousness, sleepiness, e...
Read more

Missed a Dose

If you have missed any dose of Nexpro RD 40 capsule, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your next scheduled dose. Do not take a do...
Read more

Content Details


Dr. Mansi Savla

B. Pharm, PharmD


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What does Nexpro RD 40 capsule contain?

A: Nexpro RD 40 capsule is an anti-reflux medicine containing a combination of Esomeprazole and Domperidone, used for the treatment of adult patients with gastroesophageal reflux disease (GERD).

Q: What is Nexpro RD 40 capsule used for?

A: Nexpro RD 40 capsule is used to treat gastroesophageal reflux disease (GERD) in adults. GERD is characterised by heartburn and chest discomfort due to acid regurgitating from the stomach into the food pipe.

Q: Can I take Nexpro RD 40 capsule after food?

A: No, Nexpro RD 40 capsule should be taken before food as food interacts with the absorption of this medicine. Hence, it should preferably be taken at least 1 hour before food for it to work effectively.

Q: How does Nexpro RD 40 capsule works?

A: Esomeprazole present in this capsule blocks a pump in the stomach walls and thus reduces acid production. Domperidone improves the mortality of food in the gut. Thus, it prevents it from coming back to the food pipe.

Q: Can I drink alcohol while taking Nexpro RD 40 mg capsule?

A: You should avoid consuming alcohol while on treatment with Nexpro RD 40 capsule.

Q: Is Nexpro RD 40 capsule to be taken before food?

A: Yes, Nexpro RD 40 mg capsule should be taken before food (at least an hour before meals).

Q: What time of the day shall I take Nexpro RD 40 capsule?

A: It is recommended to take Nexpro RD 40 capsule at least 30 mins before the first meal or to take it on an empty stomach.

Q: Is it safe to use Nexpro RD 40 capsule?

A: Nexpro RD 40 capsule is safe if you take it according to the dose and duration advised by your doctor. If you stop taking this tablet once you start feeling good, the chance of recurrence of the symptom increases.

Q: Can we take Nexpro RD 40 capsule and Itraconazole?

A: You should avoid taking Nexpro RD 40 capsule with Itraconazole as it reduces the absorption of Itraconazole, reducing its effect. You should consult your doctor before taking Itraconazole when on treatment with this medicine.

Q: Can I take Nexpro RD 40 twice a day?

A: Follow the exact dose and duration prescribed by the doctor. Do not stop or modify the dose on your own.

Q: Can Nexpro RD 40 cause diarrhoea?

A: Yes, you might experience diarrhoea as a common side effect of this medicine. So keep yourself hydrated to replace the lost fluids. If you feel these symptoms persistently then immediately talk to your doctor.

Q: How can I manage my condition with lifestyle changes?

A: A change in lifestyle will probably help you control and manage acid reflux and related symptoms well. Avoid alcohol and smoking, excessive consumption of soft drinks, citrus juices, tea and coffee (caffeinated drinks). Avoid spicy, oily and fast foods. Never eat late at night or just before going to bed.

Other Products from this Brand


Quick Summary

Offer Price₹126.65
You Save₹27.80 (18% on MRP)
Best OfferUse Code: 18SAVE & get 18% discount
ContainsDomperidone(30.0 Mg),Esomeprazole(40.0 Mg)
Side effectsHeadache, dizziness, nausea, vomiting, bloating
Last Updated on: 13 Dec 2021 | 10:05 PM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.