Duphaston 10mg Tablet
By ABBOTT INDIA LTD
10 Tablet(s) in Strip
₹676.37
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₹901.83
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₹67.64/tablet
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Description
Duphaston 10 mg is a prescription-only hormonal medicine. Its primary role is in the management of a range of conditions related to the female reproductive cycle, as determined by a healthcare professional. The active ingredient in this tablet is Dydrogesterone, which is prescribed to help manage and regulate certain hormonal imbalances.
The key component in each tablet is Dydrogesterone (10mg). This substance is a synthetic hormone, which means it is man-made. It belongs to a class of medicines known as progestogens, which are designed to function in a way that is similar to the natural hormones produced in a woman's body.
Dydrogesterone is specially engineered to closely mimic the actions of progesterone, a naturally occurring female hormone. Its molecular structure allows it to interact with the body's receptors, making it a form of hormonal therapy prescribed by doctors.
Natural progesterone is often called the "pregnancy hormone." It plays a crucial role in preparing the lining of the uterus for a fertilized egg. It also helps to maintain a healthy uterine environment, which is essential for sustaining a pregnancy through its early and most delicate stages.
The Duphaston 10 mg tablet is prescribed when a doctor determines that the body's own production of progesterone is insufficient for a specific health condition. It is used to supplement these levels as part of a prescribed treatment plan, providing the necessary hormonal support to manage specific health conditions and restore the body's natural balance, particularly for menstrual and pregnancy-related issues.
This medication is indicated for certain menstrual disorders. Doctors may prescribe it for irregular or absent periods, painful period cramps (dysmenorrhea), heavy bleeding, and painful symptoms of conditions like endometriosis.
Duphaston is also prescribed in certain pregnancy-related situations. For example, it may be prescribed by a gynaecologist in cases of threatened miscarriage or for women with a history of recurrent pregnancy loss where a progesterone deficiency is suspected.
As this is a prescription medicine, it is essential to use it only under strict medical supervision. Your doctor will determine the correct dosage and duration for your specific condition. Never self-medicate, and always follow your doctor’s instructions for safe and effective treatment.
Product Summary
| Offer Price | ₹676.37 |
| You Save | ₹225.46 (25% on MRP) |
| Contains | Dydrogesterone(10.0 Mg) |
| Uses | Prescribed under medical supervision for certain conditions like dysmenorrhea, endometriosis, secondary amenorrhea, dysfunctional uterine bleeding, and for luteal support. |
| Side effects | Nausea, headache, vomiting, breast tenderness, migraine, vaginal bleeding, and mild dizziness |
| Therapy | DRUGS FOR FEMALE INFERTILITY |
1 Generic Alternate(s)
Contains same composition as Duphaston 10mg Strip Of 10 Tablets
Dydrosmart 10mg Strip Of 10 TabletsBy Healing Pharma India Pvt Ltd10 Tablet(s) in StripMRP 773.44₹ 549.1418% CHEAPER₹ 54.91/Tablet
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Uses
- Prescribed to provide supplemental progestogenic activity when natural progesterone levels are insufficient.
- Functions by acting on the endometrium, which is the lining of the uterus.
- Has an effect on uterine muscle contractility, which is relevant for its use in threatened miscarriage.
- Indicated for use in specific cases of threatened miscarriage under strict medical supervision.
- Prescribed for the management of habitual abortion (recurrent pregnancy loss) linked to progesterone deficiency.
- Used to address conditions arising from a diagnosed progesterone deficiency, such as a luteal phase defect.
- Its action helps in the development and maintenance of the secretory endometrium.
- Indicated for luteal support as part of an Assisted Reproductive Technology (ART) protocol.
- Prescribed to help prepare the uterine lining for the implantation of an embryo following IVF.
- Provides an exogenous (external) source of a progestogen required during early pregnancy stages.
- Functions by providing progestogenic effects to help in the regulation of the menstrual cycle.
- Indicated for the management of dysfunctional uterine bleeding and certain menstrual irregularities.
- Prescribed for secondary amenorrhea as determined by a doctor to regulate the cycle.
- Indicated for the management of dysmenorrhea (painful menstruation) under medical guidance.
- Used in the management of menorrhagia (heavy menstrual bleeding) when prescribed by a doctor.
- Prescribed for managing symptoms associated with the gynaecological condition endometriosis.
- Its mechanism involves acting on endometrial tissue, which is relevant for its indication in endometriosis.
- Indicated for infertility that has been diagnosed by a doctor as being due to luteal insufficiency.
- Contributes to the transformation of the endometrium from a proliferative to a secretory state.
- Prescribed for the management of certain symptoms associated with Premenstrual Syndrome (PMS).
Contraindications
- If you have a known allergy or hypersensitivity to Dydrogesterone or any of the inactive ingredients in the tablet.
- If you have a known or suspected progestogen-dependent tumour (e.g., meningioma).
- If you have undiagnosed vaginal bleeding. Your doctor must determine the cause of the bleeding before you start this medication.
- If you have a serious liver disorder.
Side effects
Common Side Effects (usually mild):
- Nausea
- Headache or migraine
- Breast tenderness or breast pain
- Mild dizziness or drowsiness
- Irregular bleeding or spotting
- Bloating
Serious Side Effects (rare, but require immediate medical attention):
- Severe allergic reactions like skin rash, hives, difficulty breathing, or swelling of the face, lips, tongue, or throat
- Jaundice (yellowing of skin or eyes)
- Signs of a blood clot
- Sudden severe pain and swelling in a leg
- Sharp chest pain
- Coughing up blood
- Severe depression or mood changes
Precautions and Warnings
Pregnancy
Q:
Can I take the Duphaston 10 mg tablet during pregnancy?
A:
Yes, you can take a Duphaston 10 mg tablet during pregnancy. In fact, one of the primary uses of the Duphaston tablet in pregnancy is to support the pregnancy. It is widely prescribed by doctors for conditions like threatened miscarriage. However, you must only take it under the strict supervision of your gynaecologist.
Breast Feeding
Q:
Can I take the Duphaston tablet while breastfeeding?
A:
It is not known for sure if Dydrogesterone passes into breast milk. Therefore, it is generally not recommended to use Duphaston while breastfeeding. Please consult your doctor for advice, as they can assess the benefits versus any potential risks.
Driving
Q:
Can I drive if I have consumed a Duphaston tablet?
A:
You should be cautious. Duphaston can cause mild dizziness or drowsiness in some people. It's best to see how the medicine affects you before you drive or operate any heavy machinery. If you feel even slightly sleepy, do not drive.
Alcohol
Q:
Can I consume alcohol with Duphaston?
A:
There are no known direct interactions between alcohol and Duphaston. However, alcohol can affect your overall health and hormonal balance. It is always best to consume it in moderation and to discuss it with your doctor, especially when you are taking medication for health reasons.
Other General Warnings
Talk to your doctor if
- You have a history of liver or kidney problems.
- You have a history of depression.
- You have heart disease or circulation problems.
- Your lab tests show deranged liver function.
- You suffer from migraines.
- You have a disease called porphyria.
- You have diabetes, as this medicine can slightly affect blood sugar levels.
Directions for Use
- The Duphaston 10 mg dose and duration are highly specific to your medical condition. Always follow your doctor's prescription exactly.
- Swallow the tablet whole with a sufficient amount of water. Do not break or chew it.
- You can take the tablet with or without food. If you experience nausea, taking it with a meal may help.
- Try to take your doses at the same time each day to maintain a stable level of the hormone in your body.
- If your doctor has prescribed more than one dose per day, try to space them out evenly (e.g., one in the morning and one in the evening).
Storage and disposal
- Store Duphaston tablets in a cool, dry place at room temperature (below 30°C).
- Keep the medicine in its original blister pack until it is time to take it, to protect it from light and moisture.
- Always ensure the tablets are stored safely out of the reach and sight of children and pets.
- Do not use the tablets after the expiry date printed on the packaging.
- Dispose of any expired or unused medicine responsibly.
Quick Tips
- Duphaston is a hormonal support tablet, not a painkiller. Its job is to fix the underlying hormonal issue.
- If you are taking Duphaston for use in early pregnancy, it is crucial that you do not stop taking it suddenly.
- Always follow your doctor's instructions for tapering off the dose.
- Consistency is key. Taking your tablet at the same time every day helps to keep the hormone levels in your body stable.
- If you experience any breakthrough bleeding or spotting while on Duphaston, inform your doctor. They may need to adjust your dose.
- This medicine is part of a treatment plan. A healthy lifestyle, including a balanced diet and stress management, can also support your reproductive health.
Dosage
Overdose
An overdose of Duphaston is unlikely to cause serious harm. You might experience nausea, vomiting, or dizziness. However, if you have accidentally taken a very large dose, it is wise to contact your doctor for advice....
Missed a Dose
If you forget to take a dose of Duphaston, take it as soon as you remember. However, if it has been more than 12 hours since your missed dose, it is best to skip it and take the next dose at the usual time. Do not take a double dose to make up for a forgotten one....
Mode of Action
How Does It Work?
- To understand the many uses of dydrogesterone tablets, especially its vital role in pregnancy, it's helpful to first know about the natural hormone it supports: progesterone. Often called the master pregnancy hormone, progesterone is produced by your body after ovulation each month. Its primary job is to prepare the uterus for a potential pregnancy. It does this by making the uterine lining, known as the endometrium, thick, spongy, and rich with blood vessels, creating the perfect nourishing environment for a fertilized egg to implant and begin to grow....
- Once pregnancy is achieved, progesterone's role becomes even more critical. It acts as a natural muscle relaxant for the uterus, keeping its powerful muscles quiet and calm. This prevents contractions that could otherwise lead to the body rejecting the early pregnancy, making it essential for preventing a miscarriage. Throughout the first trimester, it also plays a vital part in helping the placenta develop, which is the lifeline that provides oxygen and nutrients from the mother to the baby....
- However, sometimes the body doesn't produce enough progesterone on its own. If levels are too low, the uterine lining may not be prepared for implantation, or the uterus may not be calm enough to sustain a pregnancy. This can lead to difficulties conceiving or an increased risk of miscarriage. This is where Duphaston provides a helping hand, offering the hormonal support your body needs during this crucial time....
- Duphaston 10 mg contains Dydrogesterone, a specially designed man-made hormone called a progestogen. Its unique benefit lies in its molecular structure, which closely resembles your body's natural progesterone. Think of the cells in your uterus as having tiny "keyholes" (receptors) that only a progesterone "key" can open to deliver the "prepare for pregnancy" message. Dydrogesterone is shaped so perfectly like the natural key that it can fit into these same keyholes and deliver the exact same vital message....
- This is how Duphaston works as a natural ally to your body. It effectively supplements your own progesterone supply, ensuring the uterine lining is perfectly prepared and that the uterus remains a safe and calm environment for the pregnancy to flourish. One of the key advantages of Dydrogesterone is that it is highly effective when taken as an oral tablet and does not cause some of the side effects, like significant drowsiness, that are associated with other types of progesterone....
Interactions
Interactions with other medicines
- Enzyme-Inducing Drugs: Certain medicines can speed up the breakdown of Dydrogesterone in your liver, making it less effective. These include some medicines for epilepsy (like Carbamazepine, Phenobarbital), certain antibiotics (like Rifampicin), and antiviral medicines for HIV....
- Herbal Remedies: The herbal supplement St. John's Wort is known to interfere with hormonal medications and should be avoided.
- Interaction with Alcohol: As mentioned, there are no direct interactions, but it's always best to be cautious with alcohol when taking medication for your health.
Content Details
WRITTEN BY
Dr. Arpit Verma
MBBS, MD, CCEBDM Diabetology
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What are the main uses of the dydrogesterone tablet?
A: The primary use of the main dydrogesterone tablet is to treat conditions caused by a lack of progesterone. This includes supporting a pregnancy (use in early pregnancy), preventing miscarriages, regulating periods, treating infertility, and managing endometriosis.
Q: What is the use of dydrogesterone in early pregnancy?
A: The use of dydrogesterone in early pregnancy is primarily to prevent a threatened miscarriage, especially if there is bleeding, and to support the pregnancy in women who have a history of recurrent pregnancy loss due to low progesterone levels.
Q: What are the most common Duphaston side effects?
A: The most common Duphaston side effects are generally mild and can include nausea, headaches, and breast tenderness. These often feel similar to the body's natural hormonal changes and usually settle down over time.
Q: Is it safe to take the Duphaston tablet during pregnancy?
A: Yes, one of the primary and well-researched uses of the Duphaston tablet in pregnancy is to support a healthy pregnancy under a doctor's care. It has been used for decades and is considered safe and effective when prescribed by a gynaecologist for specific conditions.
Q: I missed a dose of Duphaston. What should I do?
A: If you miss a dose, take it as soon as you remember. However, if it's been more than 12 hours, skip the missed dose and take your next one at the regular time. Do not take two tablets to catch up.
Q: Can Duphaston help me get my period?
A: Yes, Duphaston can help regulate your cycle. Doctors often prescribe it for a set number of days to trigger a withdrawal bleed, which results in a period. This helps to make irregular cycles more predictable.
Q: Is Duphaston a contraceptive?
A: No, Duphaston 10 mg is not a contraceptive or birth control pill. It is used to support pregnancy and regulate cycles. You can still get pregnant while taking it if you are not using another form of contraception.
Q: How long do I need to take Duphaston during pregnancy?
A: This depends entirely on your doctor's advice. For early pregnancy support, it is often prescribed through the first trimester (up to 12-14 weeks), after which the placenta takes over progesterone production. Always follow your doctor's plan.
Q: What is the approximate Duphaston 10 mg price in India?
A: The price of Duphaston 10 mg in India is quite affordable. You can get Duphaston 10 mg tablets at the best price on PharmEasy. To see the most current cost, please check the price details at the top of this page. We regularly provide exciting offers and discounts, so you always get the best value with us.
Q: How does Duphaston 10 mg help in pregnancy?
A: Duphaston 10 mg provides hormonal support by mimicking your body's natural progesterone. This helps to prepare and maintain the uterine lining, creating a stable and nurturing environment for the baby to grow, which is crucial in early pregnancy.
References
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- Health Products Regulatory Authority. Duphaston 10 mg film-coated tablets: Package leaflet [Internet]. Ireland: HPRA; [cited 2025 Oct 15].
- Health Products Regulatory Authority. Duphaston® 10 mg film-coated tablets: Summary of Product Characteristics [Internet]. Dublin: HPRA; 2017 Nov 23 [cited 2025 Oct 15].
- Katalinic A. A critical appraisal of safety data on dydrogesterone for the support of early pregnancy: a scoping review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2022;270:1–8. [cited 2025 Oct 15].
- Muneeba Jr S, Acharya N, Mohammad S. The role of dydrogesterone in the management of luteal phase defect: A comprehensive review. Cureus. 2023 Nov 3;15(11):e48194. doi: 10.7759/cureus.48194. [cited 2025 Oct 15].
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Product Details
Brand
DUPHASTON
Country of Origin
India
Expiry Date
30/01/2028
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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