Dapavel-Gm 10/1/1000 Tablet

• If you are allergic to dapagliflozin, glimepiride and metformin or any other ingredient of Dapavel Gm Tablet.
• If you have kidney disease or liver disease.
• If you drink alcohol or alcohol-containing beverages excessively or regularly.
• If you had a heart attack, shock, breathing problems or any other disease which may reduce the amount of oxygen supplied to the body tissues.
• If you have very low/very high blood sugar levels, diabetic ketoacidosis (a serious complication of diabetes) or lactic acidosis.
• If you have a severe infection or are dehydrated.

• Low blood sugar levels
• Nausea
• Vomiting
• Diarrhoea
• Loss of appetite

Other General Warnings

• You have type 1 diabetes (where your body does not produce any insulin). This medicine should not be used in such cases.
• You have diabetic ketoacidosis (a serious complication of diabetes) or develop symptoms of diabetic ketoacidosis like rapid weight loss, nausea, vomiting, excessive thirst, difficulty in breathing, unusual sleepiness, tiredness, sweet smell to your breath, sweet or metallic taste to your mouth or a different smell or colour of your urine.
• You develop symptoms of lactic acidosis like vomiting, stomach pain, muscle cramps, a general feeling of being unwell, difficulty breathing, and low body temperature after taking this medicine.
• You have heart or kidney disease.
• You have very high sugar levels or other conditions like long persisting vomiting/diarrhoea which makes you dehydrated.
• You have or had low blood pressure or take medicines to lower blood pressure.
• You often get infections of the urinary tract.
• You develop any kind of infection of the feet.
• You develop symptoms of pain, tenderness, redness, irritation, itching, unusual discharge or odour, swelling of the genitals or the area between the genitals and anus with fever.
• You are scheduled to have any major surgery soon.
• You are taking medicines called bronchodilators to treat asthma (salbutamol) or corticosteroids to treat inflammation in asthma or arthritis (fluticasone, prednisone, celestone).

• Take Dapavel Gm Tablet as a whole with sufficient water.
• Always take this medicine exactly as prescribed by your doctor.
• Do not consume more than the prescribed dose.
• Do not discontinue the medicine on your own without consulting your doctor.

• Store in a cool and dry place away from direct sunlight.
• Keep it out of reach of children and pets.

Overdose

Missed a Dose

How Does It Work?

Interactions with other medicines

• Some medicines can affect the way Dapavel Gm Tablet works or this Tablet itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
• The use of this Tablet with diuretics (furosemide, hydrochlorothiazide) may increase the risk of dehydration and low blood pressure.
• This medicine when used together with insulin and insulin secretagogues (sulphonylurea) may cause extremely low blood sugar levels.
• Dapavel Gm Tablet should not be used if undergoing X-ray with a certain type of injectable dye called iodinated contrast agents and with medicines used to treat stomach acidity (cimetidine).
• Particular care should be taken when using medicines to treat tuberculosis (rifampicin), high/abnormal cholesterol (simvastatin), immune system alteration (glucocorticoids), pain and fever (non-steroidal anti-inflammatory medicines like ibuprofen, rofecoxib), high blood pressure (furosemide, hydrochlorothiazide, ramipril, losartan).