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Rifagut 400mg Tablet
Rifagut 400mg Tablet

Rifagut 400mg Tablet

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Rifaximin(400.0 Mg)
Therapeutic classification

Medical Description

Rifagut 400 mg tablet is an antibiotic medicine containing Rifaximin as its active ingredient. It is used in treating a condition called Hepatic encephalopathy, in which there is a decline in brain function that occurs because of severe liver disease. It is also used to treat infectious diarrhoea and irritable bowel syndrome with diarrhoea. It works by killing the growth of bacteria that cause infectious diarrhoea. This medicine should be used under medical prescription, and for the duration, it is prescribed. A few side effects of this medicine are nausea, stomach pain, headache, and dizziness. Most of which are temporary but if you feel the side effects persist or your condition worsens, you should contact your doctor immediately. Tell your doctor, if you are pregnant, planning a pregnancy or are breastfeeding, and about all the medicines and supplements your take, and all the conditions or diseases you suffer from before starting this medicine. You should complete the entire treatment with this medicine and not stop it mid-way on your own without the knowledge of your doctor.
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Uses of Rifagut 400mg Tablet

Rifagut 400 mg tablet is used in the treatment of hepatic encephalopathy (a condition in which there is a loss of brain function when a damaged liver fails to remove toxins from the blood). It is also used to treat infectious diarrhoea and irritable bowel syndrome with diarrhoea.
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Contraindications of Rifagut 400mg Tablet

  • Do not use if you are allergic to Rifaximin or any other ingredients of this medicine
  • Do not use if you have a liver disease
  • Do not use if you have diarrhoea that is caused due to other factors but not bacteria, for example, viral diarrhoea.
  • Do not use if you have symptoms of blockage in the bowel, stomach pain or constipation.
  • Do not use if you have bloody diarrhoea
  • Do not use if you have diarrhoea along with fever.
  • Do not use if you experience allergic reactions with rifabutin, rifapentine or rifampicin.

Side effects of Rifagut 400mg Tablet

  • Loss of appetite
  • Stomach pain
  • Dehydration
  • Headache
  • Dehydration
  • Nausea
  • Breathing issues
  • Vomiting
  • An urgency to empty bowel

Precautions and Warnings of Rifagut 400mg Tablet


Can I take Rifagut 400 mg tablet during pregnancy?
Rifagut 400 mg tablet should not be used in pregnancy as there is limited information about its safety in human pregnancy. Consult your doctor if you are pregnant or think you may be pregnant or planning to have a baby.

Breast Feeding

Can I take Rifagut 400 mg tablet while breastfeeding?
It is unknown if Rifagut 400 mg tablet passes into human milk. Hence, you should not breastfeed while taking this medicine. Consult your doctor before using this medicine during breastfeeding.


Can I drive if I have consumed Rifagut 400 mg tablet?
You may experience dizziness while on treatment with Rifagut 400 mg tablet. Caution is needed while driving or operating machines.


Can I consume alcohol with Rifagut 400 mg tablet?
There have been no reported interactions between Rifagut 400 mg tablet and alcohol; but you should avoid consuming alcohol while on treatment.

Other General Warnings

Talk to your doctor if
You should discontinue taking Rifagut 400 mg tablet immediately if you experience severe diarrhoea while or after using it. Diarrhoea can cause dehydration. Make sure to consume enough fluids.

Mode of Action of Rifagut 400mg Tablet

How Does It Work?

Rifaximin works by disturbing the growth process of bacterial cells; therefore, the bacterial multiplication is hindered and the existing bacteria are killed or their lifecycle stops. Rifagut 400 mg tablet passes through the stomach and intestine without getting absorbed in the bloodstream and is mainly used to treat bacterial infections in the intestine.
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Directions for Use of Rifagut 400mg Tablet

Follow your doctor's instruction while taking Rifagut 400 mg tablet. You should swallow it with a glass of water, do not break, cut, or chew the tablet. You should take it regularly and preferably at a fixed time. Do not consume it more or longer than that prescribed by your doctor.
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Interactions of Rifagut 400mg Tablet

Interactions with other medicines

  • Rifagut 400 mg tablet might interact with cholera and BCG vaccine.
  • This medicine might alter the effects of other medicines such as erythromycin, diltiazem, azithromycin, warfarin and anti-fungal medications.

Interactions with food items

Rifagut 400 mg tablet might interact with grapefruit juice or the fruit, hence it should be avoided.

Storage and disposal of Rifagut 400mg Tablet

Store Rifagut 400 mg tablets in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it away from children and pets. Do not use expired or damaged medicines. Discard any unused medicine properly, do not flush in the toilet or throw it into the drain.
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Dosage of Rifagut 400mg Tablet


If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

You should never miss your dose of antibiotics as, it may lead to treatment failure. If you missed any dose of medicine take it as soon as you remember. However, if it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.
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Content Details


Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: Can I take Rifagut 400 mg tablet if I am currently following a warfarin prescription?

A: Rifagut 400 mg tablet might alter the activity of warfarin. You should provide your doctor with the prescription details as changes may be made if required in the Rifagut 400 mg tablet dosage and prescription.

Q: Can I take Rifagut 400 mg tablet if I have severe liver disease?

A: People with severe liver disease should use Rifagut 400 mg tablet with caution. You should inform your doctor about your liver condition and give your doctor a detailed medical history.

Q: I recently had antibiotic-induced diarrhoea. Can I still take Rifagut 400 mg tablet?

A: The therapeutic effects of Rifagut 400 mg tablet might change in people suffering from diarrhoea caused by antibiotics. You should inform your doctor about your medical history.

Q: Can I take Rifagut 400 mg tablet if I am allergic to azithromycin?

A: Inform the doctor about your allergic reaction in detail as Rifagut 400 mg tablet is contraindicated in people with allergic reactions to other antibiotic medications such as azithromycin.

Q: Are there any dietary guidelines to follow while taking Rifagut 400 mg tablet?

A: You should consume your meals as usual; however, avoid drinking both grapefruit juice and eating the fruit as Rifagut 400 mg tablet might interact with it.

Q: My white blood cell count was low in a recently conducted blood test. Is it due to Rifagut 400 mg tablet?

A: Abnormal test results in white blood cells is one of the common Rifagut 400 mg tablet side effects. You can continue taking Rifagut 400 mg tablet; however, you should inform your doctor about the side effect.

Q: I am currently taking antifungal medications. Can Rifagut 400 mg tablet be taken along with the antifungal medicines?

A: Rifagut 400 mg tablet might affect the therapeutic activity of antifungal medicines. You should inform your doctor about the current medications you are taking as changes might be made in the prescription (if needed).

Q: Is it okay to take an extra dose if I have missed a dose?

A: You should not take an extra dose to compensate for the missed dose. Try not to miss a dose of Rifagut 400 mg tablet because it might cause antibiotic resistance.

Q: Rifagut 200 or 400, which is a better medicine to treat diarrhea?

A: Rifagut 200 and Rifagut 400, both tablets contain Rifaximin as an active ingredient and are used to treat infectious diarrhoea. Based on the cause and severity of your infection, your doctor will prescribe you the suitable medicine. You should take the medicine as prescribed by your doctor. Do not self-medicate.

Other Variants for

Rifagut 400mg Tablet

Last Updated on: 12 Sep 2020 | 05:31 AM (IST)
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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  • Uses
  • Contraindications
  • Side effects
  • Precautions and Warnings
  • Mode of Action
  • Directions for Use
  • Interactions
  • Storage and disposal
  • Dosage
  • FAQs
  • References
  • Other Variants
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