Sibofix 400mg Tablet
By DR REDDY'S LABORATORIES LTD
10 Tablet(s) in Strip
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Sibofix Tablet contains Rifaximin. It is an antibiotic medicine used to treat infectious diarrhoea and irritable bowel syndrome with diarrhoea. It is also used in treating a condition called Hepatic encephalopathy, in which there is a decline in brain function that occurs because of severe liver disease. Sibofix Tablet works by killing the bacteria that cause infectious diarrhoea by inhibiting their growth. Inform your doctor, if you are pregnant, planning a pregnancy or are breastfeeding, and about all the medicines and supplements you take and all the conditions or diseases you suffer from before starting this medicine. Complete the entire course given by your doctor. Do not stop it midway on your own without the knowledge of your doctor.
Uses of Sibofix 400mg Tablet
Sibofix Tablet is used in the treatment of Hepatic encephalopathy (a condition in which there is a loss of brain function when a damaged liver fails to remove toxins from the blood). It is also used to treat infectious diarrhoea and irritable bowel syndrome with diarrhoea.
Contraindications of Sibofix 400mg Tablet
- If you are allergic to Rifaximin or any other ingredients of this medicine.
- If you have liver disease.
- If you have diarrhoea that is caused due to other factors but not bacteria, for example, viral diarrhoea.
- If you have symptoms of blockage in the bowel, stomach pain or constipation.
- If you have bloody diarrhoea.
- If you have diarrhoea along with fever.
- If you experience allergic reactions with rifabutin, rifapentine or rifampicin.
Side effects of Sibofix 400mg Tablet
- Loss of appetite
- Stomach pain
- Breathing issues
- An urgency to empty bowel
Precautions and Warnings of Sibofix 400mg Tablet
Can I take Sibofix Tablet during pregnancy?
Sibofix Tablet should not be used in pregnancy, as there is limited information about its safety in human pregnancy. Consult your doctor if you are pregnant or think you may be pregnant or planning to have a baby.
Can I take Sibofix Tablet while breastfeeding?
It is unknown if Sibofix Tablet passes into human milk. Hence, do not breastfeed while taking this medicine. Consult your doctor before using this medicine during breastfeeding.
Can I drive if I have consumed Sibofix Tablet?
You may experience dizziness while on treatment with Sibofix Tablet. Caution is needed while driving or operating machines.
Can I consume alcohol with Sibofix Tablet?
There have been no reported interactions between Sibofix Tablet and alcohol. Avoid consuming alcohol while on treatment.
Other General Warnings
Talk to your doctor if
You should discontinue taking Sibofix Tablet immediately if you experience severe diarrhoea while or after using it. Diarrhoea can cause dehydration. Consume enough fluids.
Mode of Action of Sibofix 400mg Tablet
How Does It Work?
Rifaximin works by disturbing the growth process of bacterial cells. Therefore, the bacterial multiplication is hindered and the existing bacteria are killed or their life-cycle stops. Sibofix Tablet passes through the stomach and intestine without getting absorbed in the bloodstream and is mainly used to treat bacterial infections in the intestine.
Directions for Use of Sibofix 400mg Tablet
- Follow your doctor's instructions while taking Sibofix Tablet. Swallow it with a glass of water. Do not break, cut, or chew the tablet.
- You should take it regularly and preferably at a fixed time. Do not consume it more or longer than that prescribed by your doctor.
Interactions of Sibofix 400mg Tablet
Interactions with other medicines
- Sibofix Tablet might interact with cholera and the BCG vaccine.
- This medicine might alter the effects of other medicines such as erythromycin, diltiazem, azithromycin, warfarin and anti-fungal medications.
Interactions with food items
Sibofix Tablet might interact with grapefruit juice or the fruit. Hence, grapefruit should be avoided.
Storage and disposal of Sibofix 400mg Tablet
- Store Sibofix Tablet in a cool and dry place, protected from direct sunlight, moisture, and heat.
- Keep it away from children and pets. Do not use expired or damaged medicines.
- Discard unused medicine properly. Do not flush it in the toilet or throw it into the drain.
Dosage of Sibofix 400mg Tablet
If you think you have taken too much of this medicine, then contact your doctor immediately or visit the nearest hospital.
Missed a Dose
You should never miss your dose of antibiotics as it may lead to treatment failure. If you missed any dose of medicine, then take it as soon as you remember. However, if it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
Q: Are there any dietary guidelines to follow while taking Sibofix Tablet?
A: You should consume your meals as usual. However, avoid drinking both grapefruit juice and eating the fruit as Sibofix Tablet might interact with it.
Q: My white blood cell count was low in a recently conducted blood test. Is it due to Sibofix Tablet?
A: Abnormal test results in white blood cells are one of the common Sibofix Tablet side effects. You can continue taking Sibofix Tablet. However, inform your doctor about the side effect.
Q: I am currently taking antifungal medications. Can Sibofix Tablet be taken along with the antifungal medicines?
A: Sibofix Tablet might affect the therapeutic activity of antifungal medicines. You should inform your doctor about the current medications you are taking, as changes might be made in the prescription (if needed).
Q: Is it okay to take an extra dose if I have missed a dose?
A: You should not take an extra dose to compensate for the missed dose. Try not to miss a dose of Sibofix Tablet because it might cause antibiotic resistance.
Q: Can I take Sibofix Tablet if I am currently following a warfarin prescription?
A: Sibofix Tablet might alter the activity of warfarin. You should provide your doctor with the prescription details as changes may be made if required in the Sibofix Tablet dosage and prescription.
Q: Can I take Sibofix Tablet if I have severe liver disease?
A: People with severe liver disease should use Sibofix Tablet with caution. Inform your doctor about your liver condition and give your doctor a detailed medical history.
Q: I recently had antibiotic-induced diarrhoea. Can I still take Sibofix Tablet?
A: The therapeutic effects of Sibofix Tablet might change in people suffering from diarrhoea caused by antibiotics. Inform your doctor about your medical history.
Q: Can I take Sibofix Tablet if I am allergic to azithromycin?
A: Inform the doctor about your allergic reaction as Sibofix Tablet is contraindicated in people with allergic reactions to other antibiotic medications such as azithromycin.
Last Updated on: 22 Mar 2021 | 04:32 PM (IST)
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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