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Paxidep Cr 25mg Tablet
Paxidep Cr 25mg Tablet
Paxidep Cr 25mg Tablet
Paxidep Cr 25mg Tablet

Paxidep Cr 25mg Tablet

10 Tablet(s) in Strip
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Paxidep Cr 25 MG Description

Paxidep Cr Tablet is a medicine used to treat anxiety disorders and panic disorders. It is a selective serotonin reuptake inhibitor (SSRI) antidepressant. The mechanism of action of this medicine is

to block the serotonin reuptake transporter (SERT) and thus increase the concentration of synaptic serotonin. It is used predominantly to treat patients with depression, and it has little or no affinity for cholinergic and alpha-adrenergic histamine receptors.


Product Summary

Offer Price₹236.00
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ContainsParoxetine(25.0 Mg)
UsesDepression, Menopausal Vasomotor Symptoms, Obsessive-Compulsive Disorder, Social Phobia, Generalised Anxiety Disorder, Panic Disorder, Premenstrual Dysphoric Disorder, Post-traumatic Stress Disorder
Side effectsNausea, dizziness, drowsiness, trouble sleeping, loss of appetite, dry mouth, blurred vision, sweating, shaking (tremor), yawning, restlessness, decreased interest in sex, inability to keep still, numbness/tingling, changes in sexual ability, muscle weakness/spasm, easy bruising/bleeding, fast/irregular heartbeat, black stools, vomit that looks like coffee grounds, eye pain/redness/swelling, seizures, widened pupils, vision changes.
Check more medicines with composition as Paroxetine(25.0 Mg)

Uses of Paxidep Cr 25 MG

  • Depression
  • Menopausal Vasomotor Symptoms (hot flushes)
  • Obsessive-Compulsive Disorder
  • Social Phobia
  • Generalised Anxiety Disorder
  • Panic Disorder
  • Premenstrual Dysphoric Disorder
  • Posttraumatic Stress Disorder

Contraindications of Paxidep Cr 25 MG

  • Hypersensitivity to paroxetine
  • Concomitant administration with thioridazine or pimozide
  • Coadministration with serotonergic medicines or concomitant use within 14 days of Monoamine oxidase inhibitor medicines increases the risk of serotonin syndrome.
  • It is contraindicated to start paroxetine in a patient who is already on linezolid or intravenous methylene blue because of the fear of precipitating serotonin syndrome. Patients with the syndrome of ...
    Read more
  • Severe kidney disease
  • Severe liver disease
  • Narrow-angle glaucoma (Optic Nerve Issue)

Side effects of Paxidep Cr 25 MG

  • Nausea
  • Dry mouth
  • Insomnia
  • Constipation
  • Diarrhoea
  • Ejaculation disorder
  • Dizziness
  • Tremor
  • Blurred vision
  • Anxiety
  • Decreased appetite
  • Nervousness
  • Hypertension
  • Weight gain
  • Angle-closure glaucoma
  • Vertigo
  • Seizure
  • Abnormal bleeding
  • Acute jaundice
  • Bone fracture

Precautions and Warnings of Paxidep Cr 25 MG



Can I take Paxidep Cr Tablet during pregnancy?
Since this medication is associated with congenital cardiovascular malformations in the newborn post-exposure in the first trimester and with newborn complications requiring prolonged hospitalisation, tube feeding, and respiratory support post-exposure in the third trimester, it is not recommended for use during pregnancy. It may harm an unborn baby and babies born to mothers who have used it during the last three months of pregnancy and may sometimes cause withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. However, since untreated mental/mood problems (such as panic attacks, depression, anxiety, and obsessive-compulsive disorder) can harm an unborn baby, the pregnant woman shouldn’t stop taking this medication unless directed by the treating doctor.

Breast Feeding

Can I take Paxidep Cr Tablet while breastfeeding?
Paxidep Cr Tablet passes into breast milk. Consult your doctor before taking Paxidep Cr Tablet while breastfeeding.


Can I drive if I have taken Paxidep Cr Tablet?
Don’t drive, use machinery, or attempt anything that requires alertness or clear vision while taking Paxidep Cr Tablet.


Can I consume alcohol with Paxidep Cr Tablet?
It isn’t advisable to consume alcohol or alcohol-based beverages while taking this medicine; since alcohol can increase the effects of Paxidep CR on the nervous system. This may result in increased dizziness, drowsiness, and difficulty in concentration.

Other General Warnings

Talk to your doctor if
  • You have suicidal tendencies.
  • You have a major depressive disorder.

Mode of Action of Paxidep Cr 25 MG

How Does It Work?

Paxidep Cr Tablet is a selective serotonin reuptake inhibitor (SSRI) that contains paroxetine. It has a highly selective blockade of serotonin transporter with little effect on norepinephrine transpor...
Read more

Directions for Use of Paxidep Cr 25 MG

  • Paxidep Cr Tablet has to be taken by mouth, with or without food, as directed by the treating doctor.
  • The chances of nausea may reduce if this medication is taken with food.
  • Crushing or chewing this medication may release all of the medicine at once, increasing the risk of side effects.
  • The dosage is based on your response to treatment, medical condition, age, associated comorbidities and other medications you may be taking.

Interactions of Paxidep Cr 25 MG

Interactions with other medicines

  • Paxidep CR should not be consumed with medicines such as:
  • Psychiatric medicine and pain killers such as
  • Buspirone
  • Fentanyl
  • Lithium
  • Tryptophan
  • Amphetamines
  • Migraine medicines such as
  • Rizatriptan
  • Sumatriptan
  • Tramadol
  • Antiplatelet medicines and Blood Thinners such as:
  • Warfarin
  • Clopidogrel
  • Aspirin
  • Ibuprofen
  • MAO (Monoamine oxidase) inhibitors such as
  • Isocarboxazid
  • Linezolid
  • Metaxalone
  • methylene blue
  • Moclobemide
  • Phenelzine
  • Procarbazine
  • Rasagiline
  • Safinamide
  • Selegiline
  • tranylcypromine
  • These medicines, if consumed together, can cause a fatal reaction.
  • Having these medicines together can cause an adverse reaction in the body. It is also possible that some of these medicines negate the efficacy of either and may also affect the removal of other medic...
    Read more

Interactions with food items

  • Root Panax
  • Ginseng
  • Marijuana
  • Fish oil triglycerides
  • St. John's wort

Storage and disposal of Paxidep Cr 25 MG

It has to be stored at room temperature away from children, pets, moisture, and light.

Dosage of Paxidep Cr 25 MG


The overdose symptoms of Paxidep Cr Tablet include irregular heartbeat, seizures, severe dizziness, and fainting. This requires urgent medical intervention.

Missed a Dose

Take your dose at the regular time. Do not double a dose to catch up. If you miss a dose, skip the dose if it is time for the next dose.

Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: Can Paxidep Cr Tablet cause problems with the bones?

A: Yes, bone fractures have been attributed to this Paxidep Cr Tablet

Q: Can Paxidep Cr Tablet affect my sex life?

A: Yes, Paxidep Cr Tablet affects sex life as it can cause decreased sexual desire and the inability to reach an orgasm in both men and women. Men may also experience abnormal erection and ejaculation.

Q: Does the use of Paxidep Cr increase the prevalence of serotonin syndrome?

A: The risk of serotonin syndrome is increased in cases of the concomitant administration with other serotonergic medicines, including tricyclic antidepressants, triptans, fentanyl, tramadol, lithium, buspirone, tryptophan, isocarboxazid, thioridazine, pimozide, intravenous methylene blue, linezolid, amphetamines, phenelzine, procarbazine, selegiline, tranylcypromine and St. John’s Wort
Product Details
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Last Updated on: 23 Feb 2022 | 09:09 AM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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