Vokanamet 50/500mg Bottle Of 60 Tablets

• If you have a known allergy to any of the components of this medicine
• If you have severe kidney problems (renal impairment)
• If you have liver disease or liver failure (hepatic impairment)
• If you have uncontrolled diabetes, diabetic ketoacidosis, or are in a diabetic pre-coma state
• If you have a severe acute medical condition, serious infection, or systemic infection
• If you are severely dehydrated
• If you have serious heart or circulatory disorders, including a recent heart attack (myocardial infarction)
• If you consume alcohol excessively
• If you have significant organ impairment

• Hypoglycaemia (especially with insulin or sulfonylureas)
• Nausea
• Vomiting
• Diarrhoea
• Abdominal pain
• Urinary tract infections
• Genital yeast infections
• Increased urination
• Thirst
• Constipation
• Metallic taste
• Reduced vitamin B12 levels

Other General Warnings

• You have kidney disease, have had a kidney transplant, or suffer from liver disease.
• You are at risk of lactic acidosis, especially if you have existing renal impairment.
• You experience severe dehydration (such as from persistent vomiting or diarrhea), as you may need to temporarily stop treatment.
• You are scheduled for major surgery; the medication must be stopped prior to the procedure.
• You notice signs of diabetic ketoacidosis, such as rapid weight loss, nausea, or a sweet, fruity smell on your breath.
• You have a history of circulatory issues, as there is an increased risk of lower limb amputation.
• You need guidance on maintaining proper daily foot care to prevent complications.
• You develop symptoms of genital yeast infections or urinary tract infections.
• You are an elderly patient, as you may require more frequent monitoring of kidney function.

• Take this medicine as a whole with sufficient water.
• Always take this medicine exactly as prescribed by your doctor.
• Do not consume more than the prescribed dose.
• Do not discontinue the medicine on your own without consulting your doctor

• Store in a cool and dry place away from direct sunlight.
• Keep it out of reach of children and pets.

Overdose

Missed a Dose

• You should never miss your blood sugar medicines as they may lead to high blood sugar and symptoms associated with them.
• However, if you missed any dose of the medication, take it as soon as you remember.
• If it's time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double amount to compensate for the missed one

How Does It Work?

• Vokanamet tablet works by combining two antidiabetic agents with complementary mechanisms. Canagliflozin inhibits SGLT2 in the kidneys, reducing glucose reabsorption and promoting urinary glucose excretion, thereby lowering blood sugar levels.
• Metformin decreases hepatic glucose production, improves insulin sensitivity, and enhances peripheral glucose uptake. Together, they help achieve effective glycemic control in patients with type 2 diabetes mellitus through reduced glucose production and increased glucose elimination.

Interactions with other medicines

• Tell your doctor about all medicines, supplements or herbals you are taking or might take to avoid any possible interaction.
• Vokanamet tablet with diuretics (furosemide, hydrochlorothiazide) may increase the risk of dehydration and low blood pressure.
• Vokanamet tablet, when used together with insulin and insulin secretagogues (sulphonylurea), may cause extremely low blood sugar levels.
• Particular care should be taken when using medicines to treat depression (St.John's wort), tuberculosis (rifampicin), fits/seizures (phenobarbital, phenytoin), HIV/AIDS (ritonavir), high/abnormal cholesterol (cholestyramine, simvastatin), heart failure (digoxin), blood clots (dabigatran).