Triomune 40mg Tablet

• Nausea
• Fatigue
• Fever
• Headache
• Vomiting
• Diarrhoea
• Abdominal pain
• Myalgias
• Blood disorders

Other General Warnings

• You develop symptoms like fatigue, nausea, loss of appetite, upper belly pain, dark urine, pale stools, or yellow skin/eyes these may be signs of serious liver problems, which are most likely in the first 6–18 weeks of treatment with Triomune tablet and can be life-threatening in both men and women.
• You develop a rash, especially one accompanied by fever, swelling, redness, blistering, or skin peeling, as this may indicate a severe skin reaction, such as Stevens-Johnson syndrome or toxic epidermal necrolysis.
• You experience unexplained tiredness, muscle pain, weight loss, new infections, or symptoms returning after starting treatment, as these could be signs of immune system changes or hidden infections becoming active.
• You are taking any new prescription, over-the-counter, herbal, or vitamin supplements, especially St. John's Wort, as these can interact with Triomune tablet or reduce its effectiveness.
• You are pregnant, planning pregnancy, or breastfeeding, since nevirapine may affect maternal and child health, and breastfeeding can pass HIV to your baby.
• You are on other medications, including birth control, liver disease drugs, seizure meds, heart rhythm medicines, or blood thinners, as this medicine can interact with many medicines and may require dose changes.
• You are drinking alcohol or using driving machinery. This medication can cause dizziness or drowsiness, and alcohol may worsen side effects.
• You have not had regular blood tests during the first months of treatment, as these are important for monitoring liver problems, severe skin reactions, and to ensure the medication is working safely.

• Triomune tablet should be taken as directed by your doctor.
• Swallow it whole with a glass of water.
• It should be taken without meals.
• It is best to take it at a fixed time for optimal results, and you should not consume it more than prescribed by your doctor.

• Store Triomune tablet in a cool, dry place, protected from direct sunlight, moisture, and heat.
• Keep it out of the reach of children and pets.

Overdose

Missed a Dose

How Does It Work?

• Lamivudine is a medicine used to treat HIV and hepatitis B by helping to lower the amount of virus in your body. It works by blocking an enzyme the virus needs to make more copies of itself. This helps slow down the infection, keeps your immune system stronger, and reduces the risk of complications. Lamivudine doesn’t cure the infection, but when taken regularly as prescribed, it helps you stay healthier for a longer period.
• Stavudine is a medicine used to treat HIV (human immunodeficiency virus). It works by blocking an enzyme that the virus needs to multiply in your body. This helps reduce the amount of HIV in your system, supports your immune system, and lowers the chance of HIV-related complications. While stavudine doesn't cure HIV, it helps you live a healthier life when taken regularly along with other HIV medications, as prescribed by your doctor.
• Nevirapine is a medicine used to treat HIV infection. It works by blocking an enzyme called reverse transcriptase, which the virus requires to replicate and produce more copies of itself. By stopping this process, nevirapine helps lower the amount of HIV in your body, supports your immune system, and reduces the risk of HIV-related illnesses. It is usually taken with other HIV medications and should be used exactly as your doctor prescribes for best results.

Interactions with other medicines

• Avoid taking Triomune tablet together with zidovudine, as they can interfere with each other’s action inside the body and reduce their effectiveness.
• Be cautious if you are taking doxorubicin or ribavirin with this medicine, as they may interact with its effects.
• If you are taking Triomune tablet, please inform your doctor about all other medications you are using, especially those that are cleared by the kidneys, such as trimethoprim (often combined with sulfamethoxazole). These may affect how this medicine works in your body.
• Taking Triomune tablet with trimethoprim/sulfamethoxazole (TMP/SMX) once daily may increase lamivudine levels, but no dose adjustment is usually necessary.
• Do not take this medicine with zalcitabine, as they may interact and prevent each other from working properly.
• Nevirapine lowers levels of many drugs by increasing liver enzyme activity (like CYP3A4/2B6), possibly reducing their effectiveness.
• Nevirapine has minimal effect on warfarin and does not affect drugs processed by other enzymes like CYP1A2 or 2D6.