Trinex 5mg Tablet
10 Tablet(s) in StripWe do not sell this product
Made by
THEO PHARMA PVT LTD
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Trifluoperazine(5.0 Mg)+Trihexyphenidyl / Benzhexol Hydrochloride(2.0 Mg) |
| Uses | Schizophrenia, Non-psychotic anxiety disorder |
| Therapy | Anti-psychotics |
| Side effects | Nausea, Constipation, Sleepiness, Dizziness, Abdominal pain, Dry mouth, Weight gain |
Assurance
available
Regulated
Medical Description
Trinex tablet is a prescription medicine used to treat schizophrenia and schizophrenia‐like illnesses. Schizophrenia is a mental disorder characterised by hallucinations, delusions, and extremely disordered thinking and behaviour episodes. Trinex tablets can also be used to treat non-psychotic anxiety disorder.
Trinex tablet is a combination medicine that contains Trifluoperazine and Trihexyphenidyl (Benzhexol Hydrochloride) as the main ingredients. This medicine works by affecting the levels of specific chemical messengers, which improve mood, thoughts, and behaviour.
Trinex tablets should be taken in dosage and duration as advised by your doctor. Do not stop taking this medicine suddenly without consulting your doctor, as it can cause clinical worsening of your condition or may lead to withdrawal-like symptoms. The common side effects of Trinex tablets are nausea, constipation, sleepiness, dizziness, abdominal pain, dry mouth, and weight gain.
Uses
- As per CDSCO and USFDA, the Trinex tablet is used for the following:
- Treatment of Schizophrenia
- Treatment of non-psychotic anxiety disorder
Contraindications
- Trinex tablet is contraindicated in the following cases:
- If you are allergic to any component of the Trinex tablet
- If you have sudden mood changes or experience suicidal ideation
- If you have low blood pressure (hypotension)
- If you have a history of stroke or are at high risk of having a stroke
- If you have Parkinson's disease or dementia
- If you have diabetes or epilepsy
- If you have heart disease
- If you have prostate or bladder problems
- If you have kidney or liver problems
- If you are pregnant or breastfeeding
- If you have respiratory issues
Side effects
- Trinex tablet has the following side effects:
- Nausea
- Constipation
- Sleepiness
- Dizziness
- Abdominal pain
- Dry mouth
- Weight gain
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have any allergic reactions after taking the Trinex tablet.
- You notice suicidal ideation or self-harming thoughts.
- You have a seizure disorder.
- You experience any severe side effects persistently.
- You have abnormal muscle movements.
- You have any previous mild liver or kidney conditions, this medicine may need a dose adjustment.
- You have withdrawal symptoms like agitation, nausea, tremor, sweating, and confusion.
- You are using any ayurvedic medicines, vitamins, and other health supplements.
Directions for Use
- Take the Trinex tablet as prescribed by the doctor.
- Take Trinex tablet with or without food or as prescribed.
- Take Trinex tablet on a regular schedule, preferably at the same time every day.
- Swallow the whole tablet orally with a glass of water. Do not break or crush the tablet.
- Do not take Trinex tablets with other medications without consulting your doctor.
- Do not stop taking Trinex tablets suddenly, as it may lead to withdrawal side effects.
- Do not exceed the dosage of Trinex tablet, even if you cannot feel its effects.
Storage and disposal
Store the Trinex tablet away from sunlight in a cool and dry spot. Ensure the medication is out of reach from children and pet animals. Keep your tablets in the pack until it is time to take them.
Do not flush Trinex tablets down into the toilet or throw away the medicines via household waste. Contact local pharma waste company for its disposal.
Do not use the Trinex tablet after the expiry date stated on the label. Dispose of the expired medicine immediately.
Dosage
Overdose
Trinex tablet overdose can result in symptoms like abdominal pain, dizziness, fainting, vomiting, breathing difficulties, sedation, fast pounding or irregular heartbeat, hypotension, and seizures. If you experience these symptoms, immediately seek emergency treatment from a nearby hospital.
Missed a Dose
If you miss a dose of the Trinex tablet, take it at the earliest. If it is already time to take the next scheduled dose, skip the missed dose and take the next dose. Consult your doctor if you have more queries regarding this issue. Do not take both doses together as it can cause overdose side effects.
Mode of Action
How Does It Work?
Trinex tablet is a combination medicine that contains Trifluoperazine-5 mg and Trihexyphenidyl (Benzhexol Hydrochloride)-2 mg as the main ingredients. Trifluoperazine belongs to the typical antipsychotic class of medications. It works by blocking dopamine receptors, resulting in the decreased effect of dopamine (a natural chemical substance in the body). It helps control the positive (hallucination, delusions, disorganised speech and thoughts) and negative symptoms (emotional coldness, low motivation) of schizophrenia.
Trihexyphenidyl (Benzhexol Hydrochloride) belongs to the anticholinergic class of medicine. It works by blocking acetylcholine. Trihexyphenidyl possesses smooth muscle-relaxing properties, which help control extrapyramidal side effects (i.e., restlessness, involuntary muscle contraction, rigidity) of Trifluoperazine.
Interactions
Interactions with other medicines
- Trinex tablet interaction with anxiety medicines, such as diazepam, clonazepam, chlordiazepoxide, alprazolam, and lorazepam, may lead to sedation and drowsiness.
- Trinex tablet interaction with blood-pressure-lowering medicine, such as amlodipine, lisinopril, losartan, or metoprolol can lead to extremely low blood pressure.
- Trinex tablet interaction with pain killers, such as morphine, oxycodone, fentanyl, hydrocodone, tramadol, and codeine, may cause sedation and drowsiness.
- Trinex tablet interaction with anti-Parkinson’s medicines such as levodopa may reduce the effects of levodopa.
- Trinex tablet interaction with antifungal medications like itraconazole and ketoconazole can reduce its effects.
- Trinex tablet interaction with antidepressants or mood-elevating medicines like fluoxetine and desipramine leads to increased blood levels of trifluoperazine and causes increased side effects.
Interactions with food items
- Continue with the usual diet unless instructed by the doctor.
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:TRINEX
Vendor Details
Fulfillment Information: Trinex 5mg Tablet will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Koch K, Mansi K, Haynes E, Adams C, Sampson S, Furtado V. Trifluoperazine versus placebo for schizophrenia. Cochrane Database of Systematic Reviews [Internet]. 2014 [cited 24 March 2022];. Available from:
- Marques L, Soares B, Silva de Lima M. Trifluoperazine for schizophrenia. Cochrane Database of Systematic Reviews [Internet]. 2004 [cited 24 March 2022];. Available from
- Drugs H. Trifluoperazine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [cited 24 March 2022]. Available from:
- DailyMed - TRIFLUOPERAZINE HYDROCHLORIDE tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2022 [cited 24 March 2022]. Available from:
- Drugs H. Trihexyphenidyl: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [cited 24 March 2022]. Available from:
- [Internet]. 2022 [cited 24 March 2022]. Available from:
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
