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Metfirst Xl 25mg Tablet
Metfirst Xl 25mg Tablet

Metfirst Xl 25mg Tablet

10 Tablet(s) in Strip
MRP 45.00
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Inclusive of all taxes
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Metoprolol(25.0 Mg)
Therapeutic classification

Medical Description

Metfirst Xl 25mg Tab contains Metoprolol. It belongs to a class of medicines called as beta-blockers.

Uses of Metfirst Xl 25mg Tab

  • It is used to treat:
  • High blood pressure
  • Chest pain (angina pectoris)
  • Irregular heart rhythm
  • Migraine

Contraindications of Metfirst Xl 25mg Tab

  • If you have an allergy to this medicine or any of the ingredients of this medicine
  • If you are suffering from heart conduction problem (like AV block) or uncontrolled heart failure
  • If you are suffering from sick sinus syndrome (abnormal heart rhythms due to malfunction of sinus node)
  • If you have continuous chest pain that occurs when you are at rest, between midnight and early morning (Prinzmetal's angina)
  • If you have reduced blood supply to your limbs (peripheral arterial disease)
  • If you have severe asthma or Chronic Obstructive Pulmonary Disease (COPD)
  • If you are suffering from untreated high blood pressure due to tumour in adrenal gland (phaechromocytoma)
  • If you have a condition called metabolic acidosis (increased acidity in your body)
  • If you are using medicines to treat irregular heart rhythm like disopyramide
  • If you have diabetes associated with frequent low blood sugar levels (hypoglycaemia)
  • If you are suffering from low blood pressure (hypotension)

Side effects of Metfirst Xl 25mg Tab

  • Low blood pressure when you stand
  • Tiredness
  • Slow heart rate
  • Dizziness
  • Headache
  • Feeling sick
  • Nausea
  • Vomiting
  • Stomach pain
  • Shortness of breath

Precautions and Warnings of Metfirst Xl 25mg Tab


Can I take Metfirst Xl 25mg Tab during pregnancy?
It is not recommended during pregnancy.

Breast Feeding

Can I take Metfirst Xl 25mg Tab while breastfeeding?
  • This medicine passes into the mother’s milk and not recommended if you are breastfeeding
  • The infant needs close monitoring for side effects like slowing of heart rate in such cases


Can I drive if I have consumed Metfirst Xl 25mg Tab?
This medicine affects your ability to drive or operate machines. Do not drive or operate machines if you experience dizziness and tiredness.


Can I consume alcohol with Metfirst Xl 25mg Tab?
Do not drink alcohol while taking this medicine as it may cause increased sleepiness or a drop in blood pressure.

Other General Warnings

Talk to your doctor if
  • You have asthma
  • If you have diabetes, caution is required, Metoprolol may cause low blood sugar levels and also change the body’s response to low blood sugar. You may not experience warning signs of low blood sugar s
    uch as an increase in heart rate, sweating, hunger pangs, headache, etc.
    Read more
  • You have a tumour of adrenal gland tissue (Pheochromocytoma)
  • You have an overactive thyroid (a condition when thyroid gland produces too much of the thyroxine hormone)
  • You are suffering from psoriasis
  • You have a circulation related problem in toes, arm, legs or fingers
  • You are suffering from a type of chest pain (Prinzmetal’s angina)
  • You recently had any heart attack, chest pain or heart surgery

Mode of Action of Metfirst Xl 25mg Tab

How Does It Work?

Metfirst Xl 25mg Tab works by slowing the heart rate and relaxing blood vessels, thus reducing high blood pressure.

Directions for Use of Metfirst Xl 25mg Tab

  • Please take it as directed by your doctor
  • Always take it at the same time everyday

Interactions of Metfirst Xl 25mg Tab

Interactions with other medicines

  • Medicines used to treat irregular heart rhythm (Amiodarone, disopyramide)
  • Medicines used to treat pain or inflammation (Indomethacin, Sulindac, Diclofenac and Foctafenine)
  • Medicines used to treat depression (Fluoxetine, Paroxetine and Bupropion)
  • Medicines used to treat mental conditions (antipsychotic) like Thioridazine
  • Medicines used to treat HIV (antiretroviral) like Ritonavir
  • Medicines used to treat allergies (antihistamine) like Diphenhydramine
  • Medicines used to treat malaria (Hydroxychloroquine, Mefloquine)
  • Medicines used to treat fungal infection of skin (Terbinafine)
  • Medicines used to treat acidity or ulcers (antacids) like Cimetidine
  • Medicines used to treat heart problems (Digoxin)
  • Medicine used in acute shock and severe allergic reaction (Epinephrine)
  • Medicine used to reduce swelling of the nose (Phenylpropanolamine)
  • Eye drops like other beta blockers
  • Medicines used to treat depression and Parkinson’s disease (Monoamine Oxidase inhibitors)
  • Medicines used to lower down the blood pressure (Clonidine, Guanfacine, Moxonidine, Methyldopa, Rilmenidine)
  • Medicines used to treat migraine (Ergotamine)
  • Medicines used to treat chest pain (Nitroglycerine)
  • General anaesthetics or local anesthetic (Lidocaine)
  • Medicines used to reduce blood sugar level like Insulin and oral antidiabetic medicines
  • Medicines used to treat high blood pressure and benign prostatic hyperplasia (Prazosine, Tamsulosin, Terazosin, Doxazosin)
  • Medicines used to treat tuberculosis (Rifampicin)

Interactions with food items

You must take this medicine dose on an empty stomach without food.

Storage and disposal of Metfirst Xl 25mg Tab

  • Store it in original packing to protect it from light
  • Try to keep out of the reach of children

Dosage of Metfirst Xl 25mg Tab


  • Symptoms of an overdose include low blood pressure, irregular heartbeat, heart failure, shock, loss of consciousness, coma, nausea, vomiting, bluish colour of the lips, tongue and skin, low levels of
    potassium or calcium in blood
    Read more
  • If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital

Missed a Dose

If you missed any dose, take it as soon as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of medicine to compe
nsate for a missed one.
Read more

Content Details


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What will be the consequences if I stop this medication on my own?

A: If you stop a beta-blocker suddenly, you can suffer from chest pain, irregular heartbeat, or heart attack. Your doctor might tell you to decrease the dose gradually. Don’t suddenly stop taking a beta-blocker without talking to your doctor.

Q: What special precautions should I follow?

A: If you experience any symptoms of dizziness, syncope, vision problems, sexual dysfunction, slowing of heart rate, etc., then immediately report to your doctor. The doctor will then adjust your dose depending on your blood pressure, heart rate, level of the medicine in your serum and other such relevant factors.

Q: What should be discussed with my healthcare provider before I start the medication of Metfirst Xl 25mg Tab?

A: You should give an account of your past or present diseases like liver, kidney or heart-related disorders, diabetes mellitus and thyroid disorders if any. You must inform your doctor about your ongoing prescription and non-prescription medicines, nutritional supplements, vitamins, herbal medicines, etc. Women should share information about pregnancy, use of oral birth control pills and other vital information like history of pregnancy-induced high blood pressure, if any.

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Last Updated on: 15 Aug 2020 | 02:33 PM (IST)
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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