Metadaxan Injection
By INCEPTA PHARMACEUTICALS LIMITED
1ml Injection in Ampoule
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Metadaxan 5 MG Description
Metadaxan Injection is a steroid medicine. It is used to reduce severe inflammations in the joints like in the case of rheumatoid arthritis, a severe case of asthma and treat many conditions of skin
allergies, eye conditions and is also used in post-surgery care. It contains dexamethasone as its active ingredient. This medicine acts by reducing the formation of inflammation-causing substances in the body. It is given by a doctor or nurse in a hospital or clinic. Do not self inject. You should not stop taking this {df}} suddenly as it may worsen the disease condition.
Product Summary
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Contains | Dexamethasone(5.0 Mg) |
Uses | Asthma, allergic reactions, rheumatoid arthritis |
Side effects | Hormonal changes, growth retardation, irregular menses, weight gain, fluid retention |
Therapy | STEROID |
Check more medicines with composition as Dexamethasone(5.0 Mg)
Uses of Metadaxan 5 MG
- Metadaxan Injection is used to manage severe inflammations of joints and autoimmune disorders like rheumatoid arthritis.
- It is given after surgery to avoid any sudden complications known as post-operative shock.
- It is used to treat various allergies associated with the skin (eczema, erythroderma) and lung disorders (asthma attack).
- It is also used in cancer therapy to reduce some specific symptoms and side effects to improve the quality of life.
Contraindications of Metadaxan 5 MG
- If you are allergic to dexamethasone or any other ingredient of Metadaxan Injection.
- If you have a bacterial infection of the blood, fungal infections, infection at joints due to TB or Gonorrhoea.
- If you have any infection at the injection site.
- Metadaxan Injection should not be used for any infection spread throughout the body.
Side effects of Metadaxan 5 MG
Side effects of Metadaxan Injection depend on the dose and duration of the treatment. You may experience a flare at the site of injection and other local reactions.
Precautions and Warnings of Metadaxan 5 MG
Pregnancy
Q:
Can I be given Metadaxan Injection during pregnancy?
A:
Metadaxan Injection is not recommended during pregnancy as there is a risk of retarded growth and a reduction in adrenal hormones in the unborn child when used for prolonged periods. Hence, it is not advisable to take this injection. However, it can be prescribed by a doctor when the benefits of this medicine to pregnant women outweigh the risks to the unborn baby.
Breast Feeding
Q:
Can I be given Metadaxan Injection while breastfeeding?
A:
It is unknown if the dexamethasone passes into the breastmilk. Hence, the Metadaxan Injection should be avoided while breastfeeding unless prescribed by the doctor.
Driving
Q:
Can I drive if I have been given Metadaxan Injection?
A:
There is limited information about the effects of Metadaxan Injection on driving. However, you should not drive if you experience any side effects which can hamper your ability to be alert.
Alcohol
Q:
Can I consume alcohol if I have been Metadaxan Injection?
A:
Although there is no known interaction of Metadaxan Injection with alcohol, it is important to consult your doctor if you drink alcohol too often.
Other General Warnings
Talk to your doctor if
- You are undergoing surgery or need a vaccination.
- You experience swelling in the tongue, rash and redness on the skin and narrowed airways.
- You experience a sudden rise in pain, swelling at the site of injection and fever.
- You have severe liver, kidney and heart-related disorders.
- You may experience psychiatric disturbance, such as feeling low, anxiety, etc.
- You have high blood pressure, head injury, migraine issue, seizures and fits.
- You have tuberculosis infection without symptoms.
- You have blood cancer or diabetes.
- You are prone to an intestinal infection, amoebiasis characterised by diarrhoea.
- You experience visual disturbances or glaucoma.
- You have ulcers, bone and muscle-related disorder.
- This injection if taken for long term treatment, can interfere with the growth and hormonal imbalance.
- Metadaxan Injection should be used carefully in the elderly and premature babies.
Mode of Action of Metadaxan 5 MG
How Does It Work?
It is a steroidal medication. Steroids are chemical substances produced in the human body and help to maintain normal body functions. Dexamethasone, the active constituent of Metadaxan Injection, acts by reducing the immune response in allergic reactions, severe inflammation and organ transplantation surgeries which results in pain, swelling and allergic-type reactions....
Directions for Use of Metadaxan 5 MG
- Metadaxan Injection will be given in the hospital by your doctor or nurse. Do not self-inject this medicine.
- Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.
Interactions of Metadaxan 5 MG
Interactions with other medicines
- Some medicines can affect the way Metadaxan Injection works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
- Medicines like Rifampicin (antibiotic), Phenytoin, and Carbamazepine (used for epilepsy and seizures), Ephedrine, and Primidone can reduce the effect of Metadaxan Injection.
- It can reduce the glucose-lowering effect of insulin and blood pressure-lowering effect of medicines used for high blood pressure and certain medicines used for heart failure such as Digoxin.
- The effect of coumarin, a blood thinner is reduced when used concomitantly with Metadaxan and there is a risk of bleeding. Continuous monitoring is recommended.
Storage and disposal of Metadaxan 5 MG
- Store Metadaxan Injection in the original package to protect it from light.
- Do not store above 25°C. Do not refrigerate or freeze.
- The product should be used immediately after dilution.
- Keep it away from children and pets.
- Do not use Metadaxan Injection if you notice the contents are of a different coloured in any way or if particles are present.
Dosage of Metadaxan 5 MG
Overdose
Metadaxan Injection will be given to you by a doctor or nurse, thus the chances of overdose are less because the treatment and the dose will be specific to the patient. However, in case of any discomfort after or during the treatment with this medicine, it should be informed immediately to the doctor....
Missed a Dose
The doctor or nurse usually gives Metadaxan Injections in the hospital or clinic. Therefore, the chances of missing a dose are less. However, if you feel that a dose has been missed, please inform your doctor and nurse....
Content Details
WRITTEN BY
Dr. Mansi Savla
B. Pharm, PharmD
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What is the action of Metadaxan Injection?
A: Dexamethasone, the active constituent of Metadaxan Injection, acts by reducing the immune response in allergic reactions, severe inflammation and organ transplantation surgeries which results in pain, swelling and allergic-type reactions.
Q: What is Steroidal Flare? What can I expect after the Metadaxan Injection is given?
A: Steroidal flare is also known as a post-injection flare, which usually occurs in the joints where the injection is given. The pain in the area of injection increases temporarily and then reduces automatically. This reaction does not occur in everyone and usually reduces within 2-3 days. The joint pain can be managed by applying ice to the affected area and using some general pain killers after consulting the doctor.
Q: How to use Metadaxan Injection?
A: Metadaxan Injection will be given to you by your treating doctors or nurse in a hospital and clinic setup. Do not self inject this injection.
Q: Can we take the Metadaxan Injection in pregnancy?
A: Metadaxan Injection is not advised to be given to pregnant women, especially in the third trimester. However, in some critical conditions, when the benefit from this injection is more than the risk to the baby, it can be given to pregnant women by a treating doctor.
Q: What is Metadaxan Injection used for?
A: Metadaxan Injection is used to reduce severe inflammations in the joints like in the case of rheumatoid arthritis, a severe case of asthma and treat many conditions of skin allergies, eye conditions and also used in post-surgery care.
References
View All
- Dexamethasone 3.3 mg/ml Solution for Injection or Infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 2 May 2022]
- HPRA - SmPC. Dexamethasone Injection [Internet]. [cited 2 May 2022]
- Dexamethasone 3.3 mg/ml Solution for Injection or Infusion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 2 May 2022]
- CDSCO - Dexamethasone [Internet]. Cdscoonline.gov.in. 2021 [cited 2 May 2022]
- Dexamethasone Phosphate Injection [Internet]. Accessdata.fda.gov. 2021 [cited 2 May 2022]
Health Articles
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