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Megatil 50mg Injection 2ml

2ml Injection
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Megatil 50 MG Description

Megatil injection is a prescription medicine. It is used for treating symptoms of schizophrenia (a mental disorder) and other psychotic disorders. Managing the symptoms of mania in bipolar disorder,

nervousness, anxiety, behaviour problems, etc., are other uses of Megatil injections. Megatil injection has a single active ingredient, chlorpromazine. It belongs to the class of antipsychotic medications. The mode of action of Megatil injections is to block certain receptors in the nervous system, which improves behaviour and mood. Psychotic conditions make it difficult for the affected person to discern between reality and imagination. This medication helps in managing such symptoms and improves the quality of life. The doctor’s directions for use of Megatil injections should be strictly followed; else, there may be side effects. This medication can be taken with or without food. Most side effects of Megatil injections do not require any medical intervention as they subside gradually. However, it is best to consult with a doctor in case of persistent side effects. Abruptly stopping this medicine can cause withdrawal symptoms such as sweating, nervousness, vomiting, and dizziness.


Product Summary

Offer Price₹3.59
You Save₹0.63 (15% on MRP)
ContainsChlorpromazine(50.0 Mg)
UsesSchizophrenia, Psychotic conditions, Bipolar mania, Nausea and vomiting, Anxiety, Hiccups, Behavioural problems like aggressiveness
Side effectsNausea, Weight gain, Constipation, Sedation, Orthostatic hypotension, Dry mouth
Check more medicines with composition as Chlorpromazine(50.0 Mg)

Uses of Megatil 50 MG

  • As per USFDA, the Megatil injection is used for the following:
  • Treatment of symptoms associated with schizophrenia, as an antipsychotic medicine (reduces strong and inappropriate symptoms, disturbed/unusual thinking, etc.)
  • Treatment of severe behaviour problems such as explosive, aggressive behaviour and hyperactivity in children from the age 1 to 12
  • Treatment of symptoms associated with psychotic disorders
  • Management of mania in bipolar disorder
  • Treatment of nausea and vomiting (for example, before surgery)
  • Treatment of intractable hiccups
  • Treatment of acute intermittent porphyria (condition in which certain natural substances build up in the body causing stomach pain, thinking and behaviour changes, and other symptoms)

Contraindications of Megatil 50 MG

  • If you are allergic to any of the ingredients of Megatil injection
  • If you are diagnosed with Reye’s Syndrome
  • If you have Neuroleptic Malignant Syndrome (NMS); immediately discontinue this injection
  • If you have severe central nervous system depression (reduces central nervous system functionality of breathing)
  • If you have narrow-angle glaucoma (increased pressure in the eye); this medicine worsens the condition
  • If you are suffering from conditions such as tardive dyskinesia (involuntary movements of the face)
  • If you have dementia (memory loss); this medicine can increase the side effects and even cause death. Dose adjustment is required
  • If you have a urinary problem; this medicine can worsen the condition
  • If you are pregnant; this medicine can have serious side effects on the foetus, especially if taken in the third trimester
  • If you are breastfeeding; consult your doctor before taking Megatil medicine
  • If you are a child or adolescent under 18
  • If the affected person is in a comatose state

Side effects of Megatil 50 MG

  • Constipation
  • Dizziness
  • Weight gain
  • Dry mouth
  • Blurred vision
  • Urinary retention
  • Orthostatic hypotension (sudden fall of blood pressure on standing)
  • Decreased sexual ability

Precautions and Warnings of Megatil 50 MG



Can I take Megatil injections during pregnancy?
Confer with your doctor before taking a Megatil injection if you are pregnant. It may be unsafe during pregnancy. There is limited information on the safety of this medicine in pregnant women, but animal research has shown some harmful effects on the foetus.

Breast Feeding

Can I take Megatil injections while breastfeeding?
Do not take Megatil injections without consulting your doctor if you are nursing. The data available on the effects of Megatil injections on breastfed babies and nursing mothers is insufficient. But it suggests that this medicine can pass into breast milk and have unwanted effects on the baby.


Can I drive if I have taken a Megatil injection?
Do not drive after taking Megatil injections. The side effects of this medicine can affect your ability to drive or operate heavy machinery. In some cases, it can cause dizziness, blurring of vision, mental confusion, nausea (mild), and drowsiness.


Can I consume alcohol with Megatil injections?
Do not consume alcohol with Megatil injections. This medicine exaggerates the effects of alcohol. It can cause side effects like lightheadedness, nausea, vomiting, loss of consciousness, dizziness, etc.

Other General Warnings

Talk to your doctor if
  • You have hypertension or high blood pressure. This medicine should be used with caution as it can increase blood pressure.
  • You have seizure syndrome. This medicine should be used with extreme caution, as it can increase the risk of seizures.
  • You have heart, lung or kidney disorder.
  • You have a planned surgery or need to be anaesthetised.
  • You are an older adult. Dose adjustment is needed to prevent excessive side effects. Due to slow metabolism in older adults, this medicine takes time to be eliminated from the body.
  • You have stayed in sunlight for a long time, been exposed to insecticides, or been administered atropine.
  • You use any herbal or Ayurvedic medicines and supplements. Your doctor will check for possible interactions.
  • Do not suddenly stop using the Megatil injections, as this can cause neuroleptic malignant syndrome (fever, altered mental status, muscle stiffness, etc.).

Mode of Action of Megatil 50 MG

How Does It Work?

The active ingredient in Megatil injection is chlorpromazine. It is a conventional or typical antipsychotic medicine. It works by blocking dopamine receptors. This results in the decreased effect of d...
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Directions for Use of Megatil 50 MG

  • Take a Megatil Injection precisely as directed by the doctor.
  • You can take a Megatil injection before or after consuming food.
  • Megatil injection should be administered by a doctor or healthcare professional.
  • Most of the time, injections can be given intramuscularly (IM) or directly into the muscle (mostly buttocks).
  • Sometimes the injection is given intravenously (into a vein through a needle) after dilution.
  • Try to keep the injection site clean and dry.
  • Do not inject this medicine by yourself.
  • If you feel any pain or burning sensation at the site of injection, notify your doctor.
  • Do not take other medication with Megatil Injection without informing your doctor.

Interactions of Megatil 50 MG

Interactions with other medicines

  • Inform your doctor about all medicines and supplements you are currently taking to avoid side effects associated with medicine interaction. The following medicines are known to interact with Megatil i...
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  • Do not take a Megatil injection if you use medication that increases blood pressure. This injection can further increase blood pressure.
  • Megatil medicine lowers the effect of blood thinners like warfarin.
  • Using certain medicines like phenytoin and propranolol can increase the amounts of both medicines in the body.
  • Using this medicine with opioid or narcotic pain relievers can increase side effects like drowsiness.
  • If you use medicines that lower lung secretions or saliva, Megatil injections will negate the effects of those medicines.
  • Do not use other antipsychotics, anticonvulsants, and anti-Parkinsonian medications with Megatil injections. It can cause adverse reactions.
  • Other medicines that Megatil injections interact with are antihistamines (allergy medicine), heart medicines, and fever-reducing medicines.

Interactions with food items

  • Try to avoid grapefruit and its juice, as this fruit can increase the levels of Megatil injection in the body. It can lead to many side effects.

Storage and disposal of Megatil 50 MG

Store Megatil injections in a dry place at room temperature. Take the injection immediately after opening the package. Do not expose Megatil medicine to direct sunlight, humidity, or wetness. Keep the...
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Dosage of Megatil 50 MG


Megatil injection overdose can cause symptoms like severe drowsiness, dry mouth, abdominal pain, dizziness, fainting, vomiting, seizures, agitation, involuntary movement of the muscles, liver failure ...
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Missed a Dose

If you have missed a dose of Megatil injection, take it as soon as you recall. If it is already time for the next scheduled dose, skip the missed dose. Do not take both of them at a time, as this can ...
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Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Can Megatil injections cause heatstroke?

A: Megatil injection can reduce sweating. This results in a rise in body temperature (hyperthermia), leading to heatstroke. This side effect is more significant in hot weather, so drinking a lot of fluids is recommended, especially in summer. However, people with kidney problems should consult a doctor before drinking excessive fluids.

Q: Will I gain weight by using Megatil injections daily?

A: Weight gain is a side effect of Megatil injections. To avoid this, try exercising regularly and maintaining a healthy lifestyle.

Q: Can I stop taking Megatil injections if I start feeling better?

A: Do not stop taking Megatil injections even if you feel well. Sudden stopping of this medicine can result in serious withdrawal problems. If you wish to stop taking this medicine, your doctor will slowly taper your dose.
Product Details
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Last Updated on: 11 Apr 2022 | 08:58 AM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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