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Chlorpromazine

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Molecule Summary

Uses
Schizophrenia, Psychotic disorders, Bipolar disorder.
Therapy
Anti-Psychotics
Side Effects
Restlessness, Agitation, Nervousness, Excessive salivation, Unable to maintain body balance, Uncontrollable muscle movements.
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Molecule Description

Chlorpromazine belongs to a group of medicines that act on the brain and treat schizophrenia and behavioural problems in children. It is an antipsychotic.

Uses

  • Management of Schizophrenia.
  • Management of Psychotic disorders (not able to differentiate between reality and non-real).
  • Management of Bipolar disorder (a mental disorder characterised by high and low moods).

Contraindications

When should one not use Chlorpromazine

If you are allergic to the medicine's active ingredient or any other substances present in the medicine.

Side effects

Common side effects of this drug are:

  • Unable to maintain body balance.
  • Restlessness
  • Agitation
  • Nervousness
  • Excessive salivation
  • Uncontrollable muscle movements mainly of the jaw, tongue, legs, and arms.

Precautions and Warnings

Pregnancy

Pregnancy

No, taking Chlorpromazine during pregnancy may cause harm to the developing baby. Studies have shown that taking Chlorpromazine during the last trimester may cause sleeping, breathing, and muscular problems.

Breast Feeding

Breast Feeding

No, taking Chlorpromazine during breastfeeding may cause suckling problems in the baby as the medicine can pass into the breast milk.

Driving

Driving

Chlorpromazine may cause sleepiness and lack of alertness, affecting your driving ability. Therefore, you must avoid driving after taking this medicine.

Alcohol

Alcohol

Consumption of alcohol may increase the risk of adverse effects and hence must not be consumed.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have a family history of blood clots.
  • You are suffering from liver or kidney problems.
  • You have fits or seizures.
  • You are suffering from the problem of high blood pressure.
  • You are suffering from depression.

Mode of Action

How Does It Work?

Chlorpromazine belongs to a group of medicines that act on the brain and changes the activity of natural chemicals in the brain.

Interactions

Interactions with other medicines

  • Medicines for indigestion and heartburn, such as antacids, make Chlorpromazine ineffective.
  • Medicines for diabetes, such as metformin, make the medicine ineffective.
  • Medicines for high blood pressure or prostate problems, such as doxazosin and terazosin, cause abnormal lowering of the blood pressure.
  • Medicines for Parkinson's disease, such as levodopa, increase the risk of abnormally low blood pressure.
  • Medicines for fits or epilepsy such as carbamazepine or phenobarbital cause a reduction in their effectiveness.
  • Medicines to manage sleep disturbances make the sleep worse or have no effect.

Interactions with food items

  • You can continue with the regular diet as food doesn't influence the effect of Chlorpromazine.

Dosage

Overdose

  • If you have accidentally taken more than the prescribed dose at one time, consult your doctor or visit the nearest emergency hospital. Symptoms of overdose of Chlorpromazine include sleepiness, unconsciousness, restlessness, fever, dry mouth, and slowed movements of the body muscles.

Missed a Dose

If you have forgotten to take the medicine on time, skip the dose missed and continue with the regular dose. Taking two doses at the same time may cause an overdose which can be fatal. Consult your doctor for more information.

Frequently Asked Questions (FAQs)

No. Chlorpromazine must not be given to children below one year of age as the safety and efficacy of the medicine have not been studied.

No. You should not stop taking Chlorpromazine suddenly on your own as the withdrawal effects may occur, which may affect your health and can be harmful. Nausea, vomiting and difficulty sleeping (insomnia), tremor (shaking), jerky body movements and the inability to control movements of the hands and body are some of the withdrawal effects of this medicine.

Some forms of this medicine may contain lactose. If your doctor has advised you not to take any type of sugar, consult your doctor before taking this medicine.

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