Imat 400Mg Strip Of 10 Tablets
10 Tablet(s) in StripMRP ₹2146.00
₹1008.62
53% OFF
Made by
ZYDUS LIFESCIENCES LIMITED
Dosage
TABLET
Expiry
Product Summary
| Uses | Blood cancer, cancer of the stomach or intestine |
| Therapy | Anti-neoplastic |
| Side effects | Headache, dizziness, cough, nausea |
| Salt Content | Imatinib(400.0 Mg) |
Assurance
available
Regulated
Medical Description
Imat 400 Tablet is an anticancer medicine used in the treatment of certain types of blood cancer and gastrointestinal stromal tumors. It is also used to treat unresectable, recurrent or metastatic dermatofibrosarcoma protuberans, a rare type of skin cancer. Imat contains imatinib as its active ingredient, which is a tyrosine kinase inhibitor. It works by blocking the growth of cancer cells and inducing cell death of abnormal cancer cells thereby slowing the progression of the disease. Your doctor will determine the correct dose and duration of treatment based on your condition and overall health.
This medicine may cause some side effects, including edema (swelling), nausea, vomiting, diarrhea, muscle cramps, rash, fatigue, abdominal pain, and general discomfort. Most side effects are temporary; however, it is essential to notify your doctor immediately if you experience rapid weight gain, persistent fatigue, or unusual bruising and bleeding. Regular monitoring may be required to ensure the safe use of Imat 400 Tablet.
Before starting treatment, inform your doctor about your complete medical history. This includes kidney, liver, or heart problems, thyroid disorders, or if you have had your thyroid gland removed. It is also important to mention any history of hepatitis B infection, as imatinib can reactivate the virus. Always disclose all medications, supplements, or herbal products you are taking to avoid possible drug interactions.
Imat 400 Tablet should be taken exactly as prescribed by your doctor. You can take it with or without food, but taking it with meals may help reduce stomach discomfort. Do not drive or operate machinery if you experience dizziness, drowsiness, or blurred vision after taking this medicine. Avoid self-medicating or changing your dose without consulting your healthcare provider.
Store Imat 400 Tablet at room temperature, away from moisture and direct sunlight, and keep it out of reach of children. Follow all instructions provided by your doctor and report any unusual symptoms promptly. Regular follow-up visits and laboratory tests are recommended to monitor your response to treatment and ensure safety throughout your therapy.
Uses
- Chronic Myeloid Leukemia (Ph+ CML)
- Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL)
- Myelodysplastic/ myeloproliferative diseases (MDS/ MPD)
- Hypereosinophilic syndrome (HES)
- Chronic eosinophilic leukemia (CEL)
- Aggressive systemic mastocytosis (ASM)
- Dermatofibrosarcoma protuberans (DFSP)
- Gastrointestinal stromal tumors (GIST)
Contraindications
Side effects
- Fluid retention & oedema
- Headache
- Dizziness
- Cough
- Nausea
- Vomiting
- Stomach pain
- Diarrhoea
- Weight gain
- Insomnia
- Taste disturbance
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have or have had a Hepatitis B infection.
- You gain weight very quickly.
- You have problems with your heart, liver, or kidneys.
- You are taking levothyroxine medication
- You experience fever, tiredness, bruising, confusion, and bleeding after taking Imat 400 tablet.
- Avoid unnecessary exposure to sunlight and wear full-sleeved clothes.
- Avoid unnecessary exposure to the sunlight, wear full-sleeved clothes and use a sunscreen with high SPF.
Directions for Use
- Imat 400 tablet should be taken as directed by your doctor.
- Swallow it whole with a glass of water; do not cut, break or chew the medicine.
- It should be taken with food to avoid stomach discomfort.
- It is best to take it at a fixed time for optimal results.
- You should not consume more than that prescribed by your doctor.
Storage and disposal
- Store Imat Tablet in a clean & dry place away from direct heat, moisture & sunlight
- Keep away from children & pets
Quick Tips
- Take the medicine exactly as prescribed by your doctor.
- Do not crush, break, or chew the tablet; swallow it whole.
- Avoid adjusting the dose or stopping treatment without consulting a medical professional.
- Report any unusual symptoms such as bruising, bleeding, fever, dizziness, or sudden weight gain.
- Avoid driving or operating machinery if you feel dizzy, drowsy, or have blurred vision.
- Keep a record of all other medications or supplements you take to prevent interactions.
- Store at room temperature, away from moisture and direct sunlight.
- Keep out of reach of children.
Dosage
Overdose
- Symptoms of overdose include nausea, vomiting, diarrhoea, rash, redness, swelling, tiredness, muscle pain, low blood count, abdominal pain, headache and decreased appetite.
- If you think you have taken too much of Imat Tablet, then contact your doctor immediately or visit the nearest hospital.
Missed a Dose
Interactions
Interactions with other medicines
- Some medicines can affect the way Imat Tablet works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Especially if you are taking medicines to treat heart problems, infections, psychiatric illnesses, fits, etc or are taking antibiotics, blood thinners, paracetamol, St John’s Wort
- Use of strong CYP3A4 inducers should be avoided. Please discuss with your doctor if you are taking dexamethasone, phenytoin, carbamazepine, rifampicin, phenobarbital, rifabutin) as they may impact desired result of imatinib.
Interactions with food items
- Can be taken with or without food.
- Taking with meals may help reduce stomach upset or nausea.
- Avoid grapefruit and grapefruit juice, as they may affect the way the medicine works.
- Maintain a balanced diet to support overall health and immune function during treatment.
- Stay hydrated by drinking plenty of water unless otherwise advised by your doctor.
Frequently Asked Questions (FAQs)
References:
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 29 Aug 2025]
- Imatinib film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 29 Aug 2025]
- GLEEVEC (imatinib mesylate) tablets for oral use, USP [Internet]. Accessdata.fda.gov. 2025 [cited 29 Aug 2025]
- MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2025 [cited 29 Aug 2025]
- Imatinib film-coated tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 29 Aug 2025]
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Manufacturer Details
Brand:IMAT
Manufacturer Name:ZYDUS LIFESCIENCES LIMITED
Address:Admac Life Sciences Plot No. 107 A & B, EPIP Phase-1, Jharmajri, Baddi, Distt-Solan 174 103 (..)
Country of Origin:India
Vendor Details
Fulfillment Information: Imat 400 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
In Case of Any Issues Contact Us
Email Id:care@pharmeasy.in
Phone Number:7666100300
Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.





















