Itraconazole
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Molecule Description
Itraconazole is used to treat fungal infections. It works by blocking the formation of the cell membrane of fungal cells by inhibiting the enzyme. It belongs to the anti-fungal class of medicines. Itraconazole is available in the form of tablets, capsules, oral powder, injection, eye drops, eye ointment, eye/ear drops, cream, gel, dusting powder, and soap. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting itraconazole.
Uses
Itraconazole is used to treat fungal infection of the skin, mouth, eyes, nails, etc
Contraindications
When should one not use Itraconazole
- You are allergic to itraconazole or similar medicines
- If you have any heart related problems
- If you are pregnant or are planning a pregnancy
Side effects
Common side effects of this drug are:
- Headache
- Dizziness
- Nausea
- Vomiting
- Diarrhoea
- Injection/applications site reactions
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You had or have heart problems like heart failure, heart attack, etc
- You have problems with your liver or kidney
- You experience shortness of breath, unexpected weight gain, swollen legs or stomach or tiredness.
Mode of Action
How Does It Work?
Itraconazole works by blocking the formation of the cell membrane of the fungus by inhibiting an enzyme, thus the fungi stop multiplying or die because of the non-formation of the complete cell membrane.
Interactions
Interactions with other medicines
- Some medicines can affect the way itraconazole works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Especially if you are taking medicines to treat your heart problems, diabetes, cancer, HIV infection, blood cholesterol problems, mental health problems, migraine, fits, allergy
Frequently Asked Questions (FAQs)
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References:
- Janssen Pharmaceutical. SPORANOX® (itraconazole) Capsules: Prescribing Information [Internet]. Titusville (NJ): Janssen Pharmaceutical; [cited 2025 Sep 16].
- Mint Pharmaceuticals Inc. PrMINT‑ITRACONAZOLE 100 mg Capsules – Product Monograph [Internet]. Mississauga (ON): Mint Pharmaceuticals Inc.; [cited 2025 Sep 16].
- Thame Laboratories. Itraconazole 10 mg/ml Oral Solution: Summary of Product Characteristics [Internet]. High Wycombe: electronic Medicines Compendium (emc); [cited 2025 Sep 16].
- Thame Laboratories. Itraconazole 10 mg/ml Oral Solution – Patient Information Leaflet [Internet]. High Wycombe: electronic Medicines Compendium (emc); [cited 2025 Sep 16].
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