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Itraconazole

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Molecule Description

Itraconazole is used to treat fungal infections. It works by blocking the formation of the cell membrane of fungal cells by inhibiting the enzyme. It belongs to the anti-fungal class of medicines. Itraconazole is available in the form of tablets, capsules, oral powder, injection, eye drops, eye ointment, eye/ear drops, cream, gel, dusting powder, and soap. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting itraconazole.

Uses

Itraconazole is used to treat fungal infection of the skin, mouth, eyes, nails, etc

Contraindications

When should one not use Itraconazole

  • You are allergic to itraconazole or similar medicines
  • If you have any heart related problems
  • If you are pregnant or are planning a pregnancy

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Injection/applications site reactions

Precautions and Warnings

Pregnancy

Pregnancy

Itraconazole must not be used during pregnancy. While taking this medicine, proper birth control measures should be taken during & after treatment for at least for 2 months after the final dose.

Breast Feeding

Breast Feeding

Itraconazole passes into breast milk in low amounts. Thus, your doctor will decide of either discontinuing the medicine or the breastfeeding after assessing the potential risk on breastfeeding infant over risk of delayed treatment on breastfeeding mother.

Driving

Driving

You may experience dizziness after taking itraconazole. thus you should be cautious while driving

Alcohol

Alcohol

Avoid consuming alcohol while taking itraconazole as it may worsen the side effects.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You had or have heart problems like heart failure, heart attack, etc
  • You have problems with your liver or kidney
  • You experience shortness of breath, unexpected weight gain, swollen legs or stomach or tiredness.

Mode of Action

How Does It Work?

Itraconazole works by blocking the formation of the cell membrane of the fungus by inhibiting an enzyme, thus the fungi stop multiplying or die because of the non-formation of the complete cell membrane.

Interactions

Interactions with other medicines

  • Some medicines can affect the way itraconazole works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking medicines to treat your heart problems, diabetes, cancer, HIV infection, blood cholesterol problems, mental health problems, migraine, fits, allergy

Frequently Asked Questions (FAQs)

Itraconazole is available in the form of tablet, capsule, oral powder, injection, eye drops, eye ointment, eye/ear drops, cream, gel, dusting powder, soap.

No, itraconazole is not an antibiotic, it is an anti-fungal medicine.

Itraconazole is an antifungal medication used to treat various fungal infections of the skin, nails, mouth, and internal organs. It is commonly prescribed for conditions such as ringworm, athlete’s foot, fungal nail infections, candidiasis, and certain systemic fungal infections. It works by stopping the growth of fungi and preventing the infection from spreading.

Itraconazole works by blocking a substance that fungi need to produce their cell membranes. Without this substance, the fungal cells cannot survive or grow, which helps the body fight the infection and gradually clears the symptoms.

Common side effects include nausea, vomiting, stomach upset, diarrhoea, headache, or mild skin rash. Rare but serious side effects include liver problems, heart failure, severe allergic reactions, or changes in heart rhythm. Contact your doctor immediately if you experience yellowing of the skin or eyes, severe fatigue, swelling, or shortness of breath.

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