Itraconazole is used for the treatment of fungal infections. It works by blocki
ng the formation of the cell membrane of fungal cells by inhibiting the enzyme. It belongs to the anti-fungal class of medicines. Itraconazole is available in the form of tablet, capsule, oral powder, injection, eye drops, eye ointment, eye/ear drops, cream, gel, dusting powder, soap. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting itraconazole.
Uses of Itraconazole
Itraconazole is used to treat fungal infection of the skin, mouth, eyes, nails, etc
Contraindications of Itraconazole
When should one not use Itraconazole
- You are allergic to itraconazole or similar medicines
- If you have any heart related problems
- If you are pregnant or are planning a pregnancy
Side effects of Itraconazole
Common side effects of this drug are:
- Injection/applications site reactions
Precautions and Warnings of Itraconazole
Can I use itraconazole during pregnancy?
Itraconazole must not be used during pregnancy. While taking this medicine, proper birth control measures should be taken during & after treatment for at least for 2 months after the final dose.
Can I use itraconazole while breastfeeding?
Itraconazole passes into breast milk in low amounts. Thus, your doctor will decide of either discontinuing the medicine or the breastfeeding after assessing the potential risk on breastfeeding infant over risk of delayed treatment on breastfeeding mother.
Can I drive if I have used itraconazole?
You may experience dizziness after taking itraconazole. thus you should be cautious while driving
Can I consume alcohol with itraconazole?
Avoid consuming alcohol while taking itraconazole as it may worsen the side effects.
Other General Warnings
Talk to your doctor if
- You had or have heart problems like heart failure, heart attack, etc
- You have problems with your liver or kidney
- You experience shortness of breath, unexpected weight gain, swollen legs or stomach or tiredness.
Mode of Action of Itraconazole
How Does It Work?
Itraconazole works by blocking the formation of the cell membrane of the fungus by inhibiting an enzyme, thus the fungi stop multiplying or die because of the non-formation of the complete cell membrane....
Interactions of Itraconazole
Interactions with other medicines
- Some medicines can affect the way itraconazole works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Especially if you are taking medicines to treat your heart problems, diabetes, cancer, HIV infection, blood cholesterol problems, mental health problems, migraine, fits, allergy
Dr. Mansi Savla
B. Pharm, PharmD
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: In which all dosage form is itraconazole available?
A: Itraconazole is available in the form of tablet, capsule, oral powder, injection, eye drops, eye ointment, eye/ear drops, cream, gel, dusting powder, soap.
Q: Is itraconazole an antibiotic?
A: No, itraconazole is not an antibiotic, it is an anti-fungal medicine.
- Sporanox (itraconazole) Capsules [Internet]. Accessdata.fda.gov. 2021 [cited 30 October 2021]
- Itraconazole - Product Monograph [Internet]. Pdf.hres.ca. 2021 [cited 30 October 2021]
- Itraconazole 100mg Capsules, hard - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 30 October 2021]
- Itraconazole 100mg Capsules, hard - Patient information leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 30 October 2021]
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