Voriconazole

Uses	Serious Fungal Infections
Therapy	Anti-Fungal
Side Effects	Nausea, Fever, Rash

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Molecule Description

Voriconazole is a Triazole antifungal medication. It is generally used to treat severe, invasive fungal infections.

Uses

To treat severe and systemic fungal infections caused by aspergillus, fusarium and candida fungus such as esophageal candidiasis infection, which may cause white patches in the mouth and throat. Other fungal infections of the skin, stomach, kidney, bladder and wounds. It is also used for the prevention of fungal infection in bone marrow transplant patients.

Contraindications

When should one not use Voriconazole

Allergic to the medicine or its content.

Side effects

Common side effects of this drug are:

Swelling (inflammation) of the cavities of the face
Skin rashes
Constipation, diarrhea or digestive problems
Nausea
Vomiting
Yellowish discoloration
Headache
Vision problems
Fever
Swelling in your hands
Ankles or feet
Sleep disturbances

Precautions and Warnings

Pregnancy

Use of this medicine during pregnancy should be avoided as it may affect the baby.

Breast Feeding

Use of this medicine in breastfeeding is not recommended as it may pass into breast milk.

Driving

This medicine may cause blurred vision. Do not drive unless you feel well.

Alcohol

Drinking alcohol can increase the risk of severe liver problems.

Other General Warnings

Talk to your doctor if

Increased sensitivity to sunlight
If you have sudden blindness or pain upon moving the eyes
Fluoride deposits in bone
Bone inflammation with pain
Heart diseases
Prolonged Q-T interval on ECG
Abnormal ECG with QT changes from birth
Hardening of the liver or abnormal liver function tests
Swelling (inflammation) of the pancreas
Low amount of magnesium, potassium and calcium in the blood

Mode of Action

How Does It Work?

The primary mode of action is the inhibition of certain chemicals essential for fungal cell growth.

Interactions

Interactions with other medicines

Voriconazole has interactions with numerous medications. Do not take this without a physician’s advice.

Interactions with food items

Avoid taking this medicine along with food. The food will make it easier for your body to absorb the medicine.

Dosage

Overdose

Seek emergency medical attention or ask for help if you think you have used too much of this medicine. Overdose symptoms may include vision problems, excessive mouth salivation, weakness, loss of balance, shortness of breath or convulsions.

Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose and do not take extra medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

You should not use Voriconazole if you are allergic to it, tell the list of medications you are using and discuss your present health conditions with your doctor before taking medicine.

Take this at least one hour before or after eating a meal. Before using this medicine, shake the oral suspension (liquid) correctly to measure a dose. Measure the liquid to be taken with a given dose measuring spoon or cup. Take the exact amount of the medicine as prescribed by your doctor.

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