Ibugesic Plus Tablet
By CIPLA LIMITED
20 Tablet(s) in Strip
₹30.98
✱
₹40.24
23% OFF
₹1.55/tablet
(Inclusive of all taxes)
✱
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Description
Ibugesic Plus Tablet is an analgesic and antipyretic medication, widely used for the short-term management of mild to moderate pain, inflammation, and fever. It contains two active ingredients: Ibuprofen (a non-steroidal anti-inflammatory drug, or NSAID) and Paracetamol (Also Known as Acetaminophen). Ibuprofen works by inhibiting the cyclooxygenase (COX) enzymes, which are essential for the production of prostaglandins, a class of chemicals in the body that cause pain, fever, and inflammation. Paracetamol enhances the pain-relieving and fever-reducing effects by acting centrally in the brain, where it blocks the generation of pain signals and regulates body temperature.
This medication is commonly used for conditions such as headaches, toothaches, muscle and joint pain, menstrual cramps, postoperative discomfort, and fever. It is especially beneficial when both pain and inflammation need to be managed simultaneously. Ibugesic Plus provides a faster onset of action and enhanced efficacy compared to either component used alone. However, its use should be limited to the lowest effective dose for the shortest possible duration to avoid adverse effects, particularly gastrointestinal irritation, liver stress, and kidney function compromise.
While Ibugesic Plus is not habit-forming, it should be used with caution in individuals with liver or kidney impairment, gastrointestinal ulcers, bleeding disorders, asthma, cardiovascular conditions, or autoimmune disorders. It is contraindicated in pregnant women (especially during the third trimester), and caution is advised in breastfeeding mothers due to the mild excretion of components into breast milk. Alcohol should be strictly avoided during treatment as it significantly increases the risk of liver toxicity and gastrointestinal bleeding. Ibugesic Plus should not be taken along with other paracetamol-containing products or NSAIDs, unless prescribed by a healthcare provider.
The tablet should be taken with or after food to minimise stomach upset. Dosing should be as per your physician's advice. Long-term or high-dose use without medical supervision can lead to serious complications such as liver failure, kidney damage, or peptic ulcer disease. It may interact with several medications, including blood thinners (e.g., warfarin), antihypertensives, antiepileptics, antibiotics (e.g., ciprofloxacin), and immunosuppressants (e.g., tacrolimus). You should always consult a doctor before initiating or combining it with other medications, especially if managing chronic conditions.
Combiflam tablet, Flexon tablet, and Imol Plus tablet also contain the same composition as Ibugesic Plus tablet.
Product Summary
| Offer Price | ₹30.98 |
| You Save | ₹9.26 (23% on MRP) |
| Contains | Ibuprofen(400.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg) |
| Uses | Pain and fever |
| Side effects | Diarrhoea, vomiting, nausea, indigestion |
| Therapy | ANALGESIC/ANTIPYRETIC |
2 Generic Alternate(s)
Contains same composition as Ibugesic Plus Strip Of 20 Tablets
Ibufyl Plus Strip Of 20 TabletsBy Leeford Healthcare Ltd20 Tablet(s) in StripMRP 38.80₹ 28.717% CHEAPER₹ 1.44/Tablet
Flexib 325mg Strip Of 20 TabletsBy Alkem Laboratories Ltd20 Tablet(s) in StripMRP 33.00₹ 25.4118% CHEAPER₹ 1.27/Tablet
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Uses
Ibugesic Plus tablet is a pain reliever. It is used to treat headaches, toothaches, body aches, muscle pain, joint pain, and fever.
Contraindications
- If you are allergic to Ibuprofen, Paracetamol, or other Ibugesic Plus tablet ingredients,
- If you have a history of allergic reactions due to painkillers like aspirin, etc.
- If you are taking medicines containing Paracetamol, Ibuprofen, or other pain medicines.
- If you have a history of ulcers or bleeding in the digestive tract.
- If you have an active clotting disorder or disorder related to the blood supply to the brain.
- If you are experiencing fluid loss (due to vomiting, diarrhoea, or not drinking enough fluids).
- If you have a kidney or liver function problem.
- If you are pregnant (last trimester), it should not be given to children under 12 years of age (<40kgs).
Side effects
- Stomach pain
- Diarrhoea
- Vomiting
- Dizziness
- Bloating
- Constipation
- Headache
- Excessive sweating
- Skin rashes & itching
Precautions and Warnings
Pregnancy
Q:
Can I take Ibugesic Plus tablet during pregnancy?
A:
Pregnant women should not consume this medicine. This medicine can hamper the growth of fetus and can also cause heart and kidney-related problems in the baby. It can delay the labour and increase the duration as both mother and baby are at a risk of bleeding disorders if consumed by pregnant women. Women who are trying to conceive and taking treatment for infertility should not take this medicine.
Breast Feeding
Q:
Can I take Ibugesic Plus tablet while breastfeeding?
A:
This medicine passes in breast milk in low concentrations and may not be harmful to the breastfed baby. It can be used for short durations and at lowest possible dose if you are breastfeeding your baby.
Driving
Q:
Can I drive if I have consumed Ibugesic Plus tablet?
A:
You may experience dizziness, drowsiness, fatigue and visual disturbances. Thus, it is advised not to drive when you are taking this medicine and experiencing these signs.
Alcohol
Q:
Can I consume alcohol with Ibugesic Plus tablet?
A:
You should avoid consuming alcohol along with this medicine. It can increase the risk of liver disease and stomach bleeding.
Other General Warnings
Talk to your doctor if
- You are an older adult.
- You have high blood pressure or heart, kidney or liver diseases.
- You may experience stomach bleeding and ulcers after taking this medicine.
- You have a history of or suffer from asthma & nasal allergy.
- You are suffering from an immune disorder, where your immune system acts against the body tissues.
- You have a hereditary disorder like G6PD deficiency or porphyria (blood disorders).
- You are an alcoholic or recently had major surgery.
- You're trying to conceive; you should discontinue this medicine.
- If you develop skin allergies like rashes, itching, bumps, blisters, etc.
Directions for Use
Swallow this tablet with a full glass of water. This medicine can be taken with or without meals but if you have a sensitive stomach, it is preferably taken with meals.
Storage and disposal
- Keep this medicine out of the reach of children.
- Store this medicine below 30°C.
Quick Tips
- Ibugesic Plus tablet is recommended for short-term use only. Do not take more than the daily prescribed dose, as it may affect the liver or cause allergic reactions.
- You should inform your doctor if you have experienced asthma, rhinitis or hives after taking aspirin or other NSAIDs.
- Before taking this medicine, inform your doctor if you are pregnant, planning on getting pregnant or breastfeeding. Also, inform your doctor about all your medications and medical history.
- Ibugesic Plus tablets should be taken with food to minimize side effects such as stomach discomfort.
- Patients with a history of stomach ulcers, kidney disease, or liver disease should avoid taking them.
Dosage
Overdose
- Taking this medicine in high doses may result in serious liver damage, coma and even death.
- Other symptoms are headache, nausea, vomiting, stomach pain, diarrhoea, unconsciousness, excitement, coma, dizziness, low blood pressure, fits, difficulty in breathing & weight loss.
- If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
Do not take a double dose if you have missed the dose. Take the next dose as soon as you remember. A minimum of 6 hour gap is recommended between 2 doses.
Mode of Action
How Does It Work?
This combination acts by interfering with the production of a chemical called prostaglandins which is responsible for swelling and pain. It also controls fever and promotes cartilage matrix synthesis.
Interactions
Interactions with other medicines
- If you are taking medicines used to treat high blood pressure, this medicine can interfere with their effect.
- Medicines like diuretics can lead to kidney damage when taken along with this medicine.
- This medicine can increase the levels of lithium and its side effects.
- Medicines that modify immune responses, like Ciclosporin & Tacrolimus, can result in kidney damage.
- Increase the risk of stomach ulcers or bleeding when taken with steroids.
- There is a risk of bleeding if you are taking medicines to thin the blood, like Warfarin and Coumarin.
- There is an increased risk of fits if you are taking this medicine with antibiotics like Levofloxacin and Ciprofloxacin.
- If you are taking medicines for treating diabetes, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat and hunger pangs.
- Medicine used to treat obstruction in the gall bladder, like cholestyramine, should not be consumed before taking this medicine.
- Medicines used to treat fits, seizures & depression include Phenobarbital, Carbamazepine and Phenytoin.
- Other medicines include Probenecid, Rifampicin, St. John's Wort, Methotrexate, Aspirin, Digoxin, and Zidovudine.
Interactions with food items
Ibugesic Plus Tablet can be taken with or without food. However, it is best taken with food to reduce side effects.
Content Details
WRITTEN BY
Dr. Arpit Verma
MBBS, MD, CCEBDM Diabetology
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Is Ibugesic plus tablet addictive?
A: No, Ibugesic plus tablet is not addictive but it is advised not to give this medicine if anyone else has the same condition as you.
Q: How many times Ibugesic Plus can be taken?
A: You should take Ibugesic plus as per the requirement. However, there should be a gap of a minimum 6-hour between 2 tablets of Ibugesic plus tablet. You must not take more than 3 tablets in 24 hours. Avoid using this medicine for more than 4 days on self-prescription.
Q: Can I give Ibugesic on plus an empty stomach?
A: Ibugesic plus tablet should be taken with or after a meal. This helps reduce the chances of stomach irritation.
Q: Can Ibugesic Plus be used to treat colds and flu?
A: No, Ibugesic Plus is not effective against colds and flu. Colds and flu are seasonal infections usually caused by a virus, and this medicine does not act against the infection-causing organism. It is used to reduce fever and relieve pain associated with the ear, nose, and throat.
Q: Ibugesic Plus vs Calpol, how do they differ?
A: Ibuprofen and paracetamol are the active ingredients in Ibugesic Plus. On the other hand, Calpol contains only paracetamol, so it is best to seek advice from a doctor on the best option for your specific needs.
Q: What are the differences between Ibugesic Plus and Crocin?
A: Ibugesic Plus combines ibuprofen and paracetamol. Crocin, on the other hand, contains only Paracetamol. It is recommended to consult with a doctor for personalized advice on the best option.
Q: Can I take Ibugesic Plus with other paracetamol-containing medicines?
A: No, do not take Ibugesic Plus Tablet with any other paracetamol-containing medicines (such as some cold and flu remedies) unless advised to do so by your doctor. Doing so can increase the risk of liver toxicity.
Q: Can long-term use of Ibugesic Plus Tablet cause side effects?
A: Yes, long-term use may lead to stomach bleeding, kidney problems, or other complications. Always use this medicine for the shortest time necessary and under the supervision of a healthcare professional.
Q: Can Ibugesic Plus Tablet be taken by patients with kidney disease?
A: Ibugesic Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be necessary depending on the severity of the condition. It is important to consult your doctor before using this medication if you have any kidney-related issues.
Q: Is Ibugesic Plus Tablet safe for patients with liver disease?
A: Ibugesic Plus Tablet should be used cautiously in patients with liver disease. Dose adjustment might be required, and medical supervision is recommended. The tablet is not recommended for individuals with severe or active liver disease.
References
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- Zupar [Internet] GSK. 2022 [cited 9 August 2022]
- Nuromol dual action pain relief 200mg/500mg tablets - summary of product characteristics (SmPC) - (EMC). (Accessed: 20 August 2024).
- Derry CJ, Derry S, Moore RA. Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. Cochrane Database Syst Rev. 2013;2013(6):CD010210. Published 2013 Jun 24. doi:10.1002/14651858.CD010210.pub2
- Thybo KH, Hägi-Pedersen D, Dahl JB, et al. Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomised Clinical Trial. JAMA. 2019;321(6):562-571. doi:10.1001/jama.2018.22039
- Derry, C. J., Derry, S., & Moore, R. A. (2013). Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. The Cochrane database of systematic reviews, 2013(6), CD010210. https://doi.org/10.1002/14651858.CD010210.pub2
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Product Details
Brand
IBUGESIC
Country of Origin
India
Expiry Date
30/03/2028
Manufacturer Details
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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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