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Molecule Description

Ofloxacin+Ornidazole is a combination medicine. It is used in adult patients to

treat diarrhoea due to mixed infections. Both ofloxacin and ornidazole belong to a group of medicines called antibiotics. Ofloxacin+Ornidazole is available in the form of tablet, capsule, syrup, suspension, injection, infusion, oral powder. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.


Uses of Ofloxacin+Ornidazole

Ofloxacin+Ornidazole is used in adults for the treatment of diarrhoea due to mixed infection

Contraindications of Ofloxacin+Ornidazole

When should one not use Ofloxacin+Ornidazole

If you are allergic to ofloxacin, ornidazole or similar medicines.

Side effects of Ofloxacin+Ornidazole

Common side effects of this drug are:

  • Headache
  • Sleepiness
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Urge to scratch
  • Skin rash
  • Injection site reactions

Precautions and Warnings of Ofloxacin+Ornidazole



Can I take ofloxacin+ornidazole during pregnancy?
Consult your doctor before using ofloxacin+ornidazole during pregnancy as limited safety information is available. Your doctor will prescribe it to you only if considered essential after assessing the benefits over risks.

Breast Feeding

Can I take ofloxacin+ornidazole while breastfeeding?
Consult your doctor before using ofloxacin+ornidazole while breastfeeding as limited data is available.


Can I drive if I have taken/used ofloxacin+ornidazole?
Avoid driving if you experience drowsiness or dizziness after taking ofloxacin+ornidazole


Can I consume alcohol with ofloxacin+ornidazole?
Avoid consuming alcohol with ofloxacin+ornidazole as it may worsen the side effects.

Other General Warnings

Talk to your doctor if
  • You are suffering from any problems with your heart, liver
  • You are pregnant or breastfeeding
  • You suffer from a condition causing muscle weakness
  • You have diarrhoea
  • You experience joint or muscle pain
  • You experience some effects on the central nervous system (CNS) like nervousness, aggression, lack of sleep, anxiety, hallucinations, depression, suicidal thoughts, etc.
  • You are suffering from Peripheral neuropathy (when the message-carrying capacity of nerve, to and from the brain and spinal cord from and to the rest of the body are damaged) like burning, tingling, n...
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  • You have clostridium difficile associated diarrhoea (CDAD)
  • You experience adverse reactions like inflammation of tendon or tendon Rupture (a tendon separates in whole or in part from tissue to which it is attached).
  • You may feel adverse reactions like fever, rashes, jaundice, allergic pneumonitis, difficulty in swallowing, swelling on the face, lips, tongue, throat, fast heartbeat or any other allergic reactions.
  • You experience sensitivity to light on exposure to natural or artificial sunlight.

Mode of Action of Ofloxacin+Ornidazole

How Does It Work?

  • Ofloxacin works by inhibiting the enzyme synthesis responsible for bacterial DNA replication. Hence, it shows the bactericidal effect.
  • Ornidazole works by destructing the DNA helical structure, which interrupts the protein synthesis and ultimately leads to the death of bacteria.

Interactions of Ofloxacin+Ornidazole

Interactions with other medicines

  • Some medicines can affect the way ofloxacin+ornidazole works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking medicines to treat your psychiatric illnesses, diabetes, gout, asthma, fits, acidity, pain and inflammation or are taking blood thinners, muscle relaxants, antacids, paink...
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Content Details


Dr. Arpit Verma

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What is Ofloxacin+Ornidazole used for?

A: Ofloxacin+Ornidazole is used to treat diarrhoea due to mixed infection in adult patients.

Q: In which all dosage forms is Ofloxacin+Ornidazole available?

A: Ofloxacin+Ornidazole is available in the form of tablet, capsule, syrup, suspension, injection, infusion, oral powder.
Last Updated on: 22 Dec 2021 | 10:51 AM (IST)

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