O2 Tablet

• If you are allergic to ofloxacin, ornidazole, or any ingredients of the O2 tablet.
• If you are allergic to a specific type of medicine called Fluoroquinolone (ask your doctor or nurse if you are not sure).
• If you have or have had experienced fits or seizures in the past or had epilepsy.
• If you had a swelling and inflammation of tendons (tissues connecting muscles to bones) in the past after use of the same drug or drugs of the same class whose name ends with a suffix -floxacin
• If you are pregnant, planning to have a baby, or breastfeeding.
• Patients with latent or actual defects in glucose-6-phosphate dehydrogenase (G6PD) activity may be prone to haemolytic reactions (leading to destruction of Red Blood Cells and Anemia) when treated with this drug.

• Nausea or a metallic taste
• Loose motions
• Stomach discomfort
• Headache or dizziness
• Loss of appetite

• Difficulty sleeping, or vivid dreams
• Dark urine, which ornidazole can cause and which is harmless
• A rash or itching
• Thrush, or a change in vaginal discharge

• Pain, swelling or tenderness in a tendon - most often the back of the ankle - or a snapping sensation. Stop the medicine, rest the limb, and contact your doctor. This can happen early and occasionally after the course has finished.
• New tingling, numbness, burning or weakness in the hands or feet.
• Confusion, agitation, hallucinations, depression, or thoughts of self-harm.
• A fit or seizure.
• Severe or watery diarrhoea, especially with fever or stomach cramps, during or weeks after the course.
• Severe sunburn or blistering after even brief sun exposure.
• A fast or irregular heartbeat, or fainting.
• Swelling of the face, lips or throat, difficulty breathing, or a rash with blistering or peeling.
• Yellowing of the skin or eyes, or dark urine with pale stools.

Other General Warnings

• You developed swelling and pain in tendons (tendonitis) after starting the treatment. You must stop the medicine immediately and contact the doctor.
• You have diabetes and are on insulin or medications for Diabetes. O2 may cause blood glucose to fall. If you start feeling symptoms of hypoglycemia like anxiousness, blurred vision, cold sweats, confusion, rapid heartbeat or tremors then check you blood sugar, consider taking glucose, contact the doctor immediately and stop the O2.
• You have a condition called myasthenia gravis (weakness or fatigue of muscles).
• You experience suicidal thoughts or feel low or anxious, immediately inform your doctor.
• You are having or have a history of a psychotic disorder like schizophrenia
• You experience fits or have a history of fits, seizures or epilepsy.
• You feel restlessness, lightheadedness, confusion or hallucinations.
• You experience allergic reactions, such as fever or rashes.
• You have kidney, liver, or heart problems.
• You have glucose-6-phosphate dehydrogenase deficiency (an inherited disorder that affects red blood cells).
• You have a family history of Long QT syndrome, have low Potassium and Magnesium levels, are elderly, or are taking antidepressants or other drugs that are known to increase the QT interval, you should take O2 cautiously.
• O2 should be used with extreme caution in patients with aortic dissection or heart valve issues, and in patients whose condition predisposes them to dissection and heart valve issues, such as Marfan syndrome, Ehlers-Danlos syndrome, Behçet’s disease, Turner Syndrome, Takayasu arteritis, Giant cell arteritis, or infective endocarditis. The risk is further increased if such people are also on steroids for the management of the above-mentioned conditions.

• Take O2 tablets as directed by your doctor, with or without food. Do not crush, break or chew the tablet. Complete the course of antibiotics for effective infection control.

• Store O2 tablet in a cool and dry place, protected from light.
• Keep it out of the reach of children and pets.

• If you start feeling better within a few days, do not stop taking this medication. To ensure effective treatment, always complete the entire course of antibiotics.
• Inform your doctor about your full medical history and whether you are currently breastfeeding, planning pregnancy, or pregnant before starting treatment with an O2 tablet.
• O2 tablets may increase sensitivity to UV radiation. Protect your skin outdoors with sunscreen (SPF 30+) and clothing.
• O2 tablets are not recommended for pregnant or breastfeeding women, children, or adolescents under 18 years old, and should be used cautiously in elderly patients.
• Finish the whole course even once you feel better, unless your doctor tells you to stop.
• No alcohol during the course or for a few days afterwards.
• Keep milk, curd, antacids and mineral supplements at least two hours away from each dose.
• Stop and contact your doctor if you have tendon pain or swelling, especially at the back of the ankle, and rest the limb. Avoid strenuous exercise during the course.
• Stop and seek advice if you develop new tingling, numbness, or weakness in the hands or feet.
• Tell your doctor about any history of epilepsy, nerve problems, tendon trouble, heart rhythm problems, or mental health conditions before starting.
• Report severe or watery diarrhoea, even if it starts weeks after the course has finished.

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