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Molecule Description

Rabeprazole+Domperidone is used for the treatment of gastrointestinal reflux di

sease (GERD). It works by reducing the amount of acid produced in the stomach and improves motility in the gut. Thus, it reduces the backflow of stomach content to the food pipe. Rabeprazole+Domperidone is available in the form of tablet, capsule. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from before starting Rabeprazole+Domperidone.


Uses of Rabeprazole+Domperidone

Rabeprazole+Domperidone is used to treat gastrointestinal reflux disease (GERD).

Contraindications of Rabeprazole+Domperidone

When should one not use Rabeprazole+Domperidone

  • If you are allergic to Rabeprazole+Domperidone.
  • If you have problems with your heart, liver or kidney.
  • If you are suffering from bleeding in the digestive system.
  • If you are pregnant, planning to get pregnant or are breastfeeding.
  • If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
  • If you are taking any medications that may affect the contraction of the heart muscle (QT prolongation).

Side effects of Rabeprazole+Domperidone

Common side effects of this drug are:

  • Headache
  • Nausea
  • Stomach pain
  • Diarrhoea
  • Dry mouth
  • Weakness
  • Skin rash

Precautions and Warnings of Rabeprazole+Domperidone



Can I take Rabeprazole+Domperidone during pregnancy?
It is not advised to take Rabeprazole+Domperidone during pregnancy until it is considered essential by the doctor and potential risks justify the benefits.

Breast Feeding

Can I take Rabeprazole+Domperidone while breastfeeding?
Rabeprazole+Domperidone passes in the breastmilk in a small amount. Your doctor may prescribe you this medicine while you are breastfeeding, only if it is necessary. Inform your doctor if you are a nursing mother.


Can I drive if I have consumed Rabeprazole+Domperidone?
Rabeprazole+Domperidone may cause sleepiness, thus you need to be cautious while driving.


Can I consume alcohol with Rabeprazole+Domperidone?
Avoid consuming alcohol with Rabeprazole+Domperidone, as it may worsen the side effects.

Other General Warnings

Talk to your doctor if
  • You are suffering from any heart (associated symptoms like palpitations, difficulty in breathing, unconsciousness), liver or kidney disease.
  • You have a stomach tumour.
  • You have a history of fractures or have osteoporosis or are taking steroids.
  • You develop watery/black stools or fever after taking this medicine.
  • You have low levels of vitamin B12.
  • Your blood magnesium levels may drop if you are taking Rabeprazole+Domperidone for more than three months. Your doctor may perform regular tests.
  • You develop skin lesions, especially in the sun-exposed area, after taking this medicine.
  • You are taking medicines to treat HIV.
  • Taking Rabeprazole+Domperidone for more than one year may increase the chances of developing bone fractures.

Mode of Action of Rabeprazole+Domperidone

How Does It Work?

  • A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Rabeprazole binds to this proton pump in stomach cells, thus blocking acid secretion.
  • Domperidone increases the motility of the stomach and intestines so that acid does not reflux back into the food pipe.

Interactions of Rabeprazole+Domperidone

Interactions with other medicines

  • Some medicines can affect the way Rabeprazole+Domperidone works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking medicine to treat your heart problems, mental health problems, fungal or bacterial infections or are taking blood thinners.
  • Rilpivirine should not be used along with this medicine.
  • Medicines like disopyramide, amiodarone, medicines to treat psychiatric problems like haloperidol, Citalopram, antibiotics like erythromycin, levofloxacin, azithromycin, antifungals like Pentamidine, ...
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Dosage of Rabeprazole+Domperidone


Symptoms of overdose may include drowsiness, confusion, mood disorders, altered consciousness. Seek urgent medical help if you suspect an overdose.

Missed a Dose

If you have missed any dose of Rabeprazole+Domperidone, then take it as soon as you remember. If it is already time for the next dose, then skip the missed dose and follow the regular dosing schedule....
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Content Details


Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: Is Rabeprazole+Domperidone a steroid?

A: No, Rabeprazole+Domperidone is not a steroid. It is an anti-reflux medicine.

Q: In which all dosage forms is Rabeprazole+Domperidone available?

A: Rabeprazole+Domperidone is available in the form of tablet, capsule.
Last Updated on: 26 Oct 2021 | 10:06 PM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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