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Zisper Forte Tablets

10 Tablet(s) in Strip
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Zisper Forte Tablets Description

Zisper Forte Tablet is a fixed-dose combination tablet consisting of two medicines, Risperidone and Trihexyphenidyl. It is an antipsychotic medicine helpful in schizophrenia, manic disorder, and diss

ociative personality disorders. Risperidone is an atypical antipsychotic that reduces the effect of dopamine hormone, a chemical that elevates mood. Trihexyphenidyl belongs to a class of medications called Antimuscarinics. It relaxes the muscles and works on nerve impulses that control muscle functions. When used as a fixed-dose combination, the side effects caused by the antipsychotic treatment are reduced. Uses of Zisper Forte tablets also include their use in the reduction of symptoms similar to Parkinson's disease. In schizophrenia, people lose touch with reality. There can be restlessness, irritable mood, sleeplessness, and split-personality traits. Zisper Forte tablets reduce these symptoms by their action against dopamine and serotonin. Directions for use of Zisper Forte tablets should be strictly followed. It is a prescription medicine available as a mouth-dissolving formulation. It should be taken as prescribed by the doctor. Zisper Forte tablets should not be stopped without medical advice. Common side effects of Zisper Forte tablets include dry mouth, sleep disturbance, nausea, headaches, dizziness, and constipation.


Product Summary

Offer Price₹67.60
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ContainsRisperidone(4.0 Mg) + Trihexyphenidyl / Benzhexol Hydrochloride(2.0 Mg)
UsesSchizophrenia, Bipolar disorder, Mania, Dissociative personality traits
Side effectsDizziness, Dry mouth, Day time sleepiness, Weight gain, Nausea and vomiting, Headache
Check more medicines with composition as Risperidone(4.0 Mg) + Trihexyphenidyl / Benzhexol Hydrochloride(2.0 Mg)

Uses of Zisper Forte Tablets

  • As per CDSCO, Zisper Forte tablets are used in the treatment of:
  • Bipolar Disorder during manic episodes (irritable, elevated mood, and restlessness)
  • Schizophrenia (suicidal thoughts, hallucinations, and delusions)
  • Dissociative personality disorders

Contraindications of Zisper Forte Tablets

  • Do not take Zisper Forte tablets or use caution:
  • If you are allergic to any active components of Zisper Forte tablets
  • If you are pregnant, planning to conceive, or lactating.
  • If you are an older adult over 65; kindly consult your doctor and know the risks and benefits.
  • If you have been diagnosed with high blood pressure, urinary problems, prostatic complaints, glaucoma, heart issues, kidney or liver disease.
  • If you have been diagnosed with Depression
  • If you have been diagnosed with Parkinson's disease
  • If you have been diagnosed with Neuroleptic Malignant Syndrome
  • If you have been diagnosed with myasthenia gravis
  • If you have suicidal tendencies

Side effects of Zisper Forte Tablets

  • Side effects of Zisper Forte tablets include:
  • Dizziness
  • Dry mouth
  • Day-time sleepiness
  • Weight gain
  • Nausea and vomiting
  • Headache
  • Difficult urination

Precautions and Warnings of Zisper Forte Tablets



Can I take Zisper Forte tablets during pregnancy?
Zisper Forte tablets can be taken during pregnancy. This medicine poses only a small risk to your baby. Stopping the medicine may pose a greater risk to you. However, this needs to be decided by your doctor. Do not stop taking your medicine unless your doctor advises so. You may need to visit an antenatal clinic with an obstetrician.

Breast Feeding

Can I take Zisper Forte tablets while breastfeeding?
Zisper Forte Tab passes through breast milk in small quantities. A few side effects in babies have been reported. A doctor will decide if you should continue taking this medicine as a nursing mother. If you choose to nurse while on treatment with Zisper Forte tablets, keep an eye on your newborn for any changes in behaviour.


Can I drive if I have taken a Zisper Forte tablet?
Zisper Forte tablets can cause adverse effects like sleepiness and blurred vision affecting your ability to drive or operate heavy machinery. It is advisable to avoid driving after taking this medicine.


Can I consume alcohol with Zisper Forte tablets?
Avoid consuming alcohol with Zisper Forte tablets, as alcohol can make you feel unsteady on your feet and sleepier.

Other General Warnings

Talk to your doctor if
  • You have a known allergy to any active or inactive components of this medicine.
  • You have a history of allergies.
  • You have any major side effects from this medicine.
  • You are pregnant or planning to conceive.
  • You use oral contraceptive pills.
  • You take other medicines for your health conditions. Inform your doctors of your complete medical and treatment history.

Mode of Action of Zisper Forte Tablets

How Does It Work?

Zisper Forte tablets work by a dual mechanism of two medicines. The Risperidone component acts on neurotransmitters like dopamine in the brain. It has anti-dopaminergic action and helps in balanci...
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Directions for Use of Zisper Forte Tablets

  • Zisper Forte Tab is a mouth-dissolving tablet. Please keep your hands dry, open the pack of tablets, remove a tablet and place it on your tongue. The tablet will start dissolving in a few seconds. You...
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  • The dose and duration should be as advised by your doctor. Do not make any changes on your own.
  • Zisper Forte tablets can be taken before or after food.

Interactions of Zisper Forte Tablets

Interactions with other medicines

  • Zisper Forte tablets, if taken with sedatives like Diazepam, Morphine, Tramadol, Chlorphenamine, can make you more sleepy.
  • Anti-epileptic medicines such as phenytoin or carbamazepine can interact with Zisper Forte tablets.
  • Anti-tuberculosis medicine (Rifampicin) can interact with Zisper Forte tablets.
  • Beta-blockers that slow the heart rate and anti-hypertensive medicines can interact with Zisper Forte tablets.
  • Medicines for Parkinson's disease like levodopa can interact with Zisper Forte tablets.
  • Diuretics like furosemide or chlorothiazide can interact with Zisper Forte tablets.

Storage and disposal of Zisper Forte Tablets

Keep this medicine in its original packaging. Store it at room temperature away from excess sunlight, heat, and moisture. Keep away from the reach of children and pets. Expired or extra medicines ...
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Dosage of Zisper Forte Tablets


Zisper Forte tablet overdose can lead to symptoms like sleepiness, dizziness, fast heartbeat, seizure, and unusual body movements. If you overdose on Zisper Forte tablets and experience any of these s...
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Missed a Dose

In case you missed a dose of your Zisper Forte tablet at least 12 hours before the next scheduled dose, take it as soon as you remember. If you missed a dose with less than 12 hours left for the next ...
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Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: Is Zisper Forte tablet habit-forming or addictive?

A: There is no evidence that Zisper Forte tablets are addictive. However, if taken with addictive substances, it comes across as addictive.

Q: Will Zisper Forte tablets affect the efficacy of my contraceptive pills?

A: Zisper Forte tablets will not affect contraception of any type, including hormonal or emergency pills. However, in case of vomiting or diarrhoea, the contraceptive medicine might not work.

Q: Will Zisper Forte tablets affect my fertility?

A: While rare, it is possible that Zisper Forte tablets affect your hormones and, in turn, cause sexual problems in both partners. It can also lead to irregular menstrual cycles. Talk to your doctor beforehand if you have concerns about any of these problems.
Product Details
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Last Updated on: 14 Mar 2022 | 10:03 AM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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