Risperidone+Trihexyphenidyl / Benzhexol Hydrochloride

Uses	Schizophrenia, bipolar disorder, mood alterations
Therapy	Anti-Psychotics
Side Effects	Nausea, dizziness, vomiting, blurred vision

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Molecule Description

Risperidone+Trihexyphenidyl / Benzhexol Hydrochloride is a combination medicine containing risperidone and trihexyphenidyl (benzhexol hydrochloride). The medication is used in the treatment of Schizophrenia and manages symptoms like muscle spasms, rigidity associated with Parkinson's disease, tremors, jerks, etc.

Uses

Schizophrenia
Bipolar disorder
Mood related disorders

Contraindications

When should one not use Risperidone+Trihexyphenidyl / Benzhexol Hydrochloride

If you are allergic to risperidone, trihexyphenidyl or any other ingredient of this medicine.
If you have glaucoma.

Side effects

Common side effects of this drug are:

Common side effects:
Sleepiness
Dizziness
Headache
Fatigue
Nausea
Vomiting
Constipation
Diarrhoea
Chest infection- bronchitis, pneumonia, sinus infection
Vision- blurry
Weight gain/ loss
Lack of control of urinary habits
Speech- slurred
Rare side effects:
Body pain
Skin rashes
Pain in abdomen
Dryness in the mouth (xerostomia)

Precautions and Warnings

Pregnancy

No, Risperidone+Trihexyphenidyl / Benzhexol Hydrochloride is not advised to be taken in pregnancy until absolutely necessary. Furthermore, consultation with respected doctors is most importantly advised.

Breast Feeding

No, it is unsafe for a lactating mother to consume this medicine. One should consult the physician, discuss the benefits and side-effects, and then only proceed with this medicine.

Driving

No. It is not safe to drive after taking this medicine. Since Risperidone+Trihexyphenidyl / Benzhexol Hydrochloride interferes with the chemical messengers in the nervous system, it alters the ability to do anything that requires focus and concentration. Also, blurry vision, dizziness, etc., may hamper the driving skills. So it is advised not to drive when someone is taking the medication.

Alcohol

No, this medicine causes dizziness, impaired vision, inability to focus, etc., so it is advised not to be taken along with alcohol.

Other General Warnings

Talk to your doctor if

You are pregnant or lactating.
You are taking other centrally-acting medications like antihistamines, benzodiazepines. It should not be taken along with these medications without consulting the benefits and drug interactions with the doctor.
You want a prescription for a child below 18 years of age. Children below 18 should not consume this medicine.
You are experiencing severe side effects. Some side effects are common, but if the side effects are causing more uneasiness than the symptoms, then a consultation with the doctor/physician is required.
You want to stop taking the medication. Risperidone+Trihexyphenidyl / Benzhexol Hydrochloride should not be stopped suddenly, as it has the potential of causing withdrawal symptoms.
You have had heart conditions like stroke.
You have diabetes.
You have kidney or liver-related problems.
You have a weakened immune system.
You have prostate-related problems.
You have digestive disorders like heartburn, indigestion.
You have myasthenia gravis.
You feel rigid movements in the face or tongue.

Mode of Action

How Does It Work?

This medicine changes the action of chemical messengers, called Dopamine and Serotonin. These are released to and from the brain. These messengers cause a change of perception, leading to seeing or hearing unrealistic things, thus causing hallucinations. Risperidone+Trihexyphenidyl / Benzhexol Hydrochloride alters mood, thinking, and well-being and behaviour.

Interactions

Interactions with other medicines

This medicine can interact with various drugs like-
Tramadol
Rifampicin
Carbamazepine
Quinidine
Clozapine
Antidiabetic medicines
Levodopa
Atenolol
Antihistamine
Antihypertensive medicine, causes excess fall in blood pressure

Interactions with food items

Taking this medicine with alcohol is not advised because alcohol may further elevate the feeling of nausea, sleepiness, confusion, etc., Also, alcohol alters rational thinking, so it is against advice to do any activity that needs attention and focus, like driving, working, etc.

Dosage

Overdose

It is advised to take this medicine only after consulting a doctor. The dose varies from person to person. It is highly recommended not to take it in higher doses than prescribed. If you think you have taken too much of this medicine, contact your doctor or the nearest hospital immediately. Overdose can cause serious and irreversible damages to the mind and body.

Missed a Dose

You should strictly take Risperidone+Trihexyphenidyl / Benzhexol Hydrochloride medicine at the same time every day. If a person has skipped or forgotten to take a dose, they should take it immediately. However, if it is the time for the next dose, then follow the regular schedule and do not take a double dose.

Frequently Asked Questions (FAQs)

It may take 4-6 weeks to see any effects of the medication. Please do not alter the dose as per the effects you witness. Consult your doctor for any change in prescription

Yes, the medication may cause weight gain. Eating healthy and exercising are important when taking this medicine.

The medication may cause dry mouth at times. Maintaining good oral hygiene is in general important; however, it becomes more important when undergoing treatment that involves Risperidone+Trihexyphenidyl / Benzhexol Hydrochloride. Drink water for dry mouth.

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