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Zaptra 12.5mg Strip Of 10 Tablets

10 Tablet(s) in Strip
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Zaptra 12.5mg Strip Of 10 Tablets Description

Zaptra is a prescription tablet manufactured by Intas Pharmaceuticals Ltd. It is from the drug class of antidepressants and is used to treat depression. Zaptra tablets contain paroxetine (12.5 mg) an

d clonazepam (0.5 mg). Depression is a mood condition in which a person's daily activities are disrupted by feelings of melancholy, dissatisfaction, anger, hopelessness, or loss. Depression has no established cause; however, it has been linked to mental health issues, trauma, family history, drug use, and physiological diseases. Some chronic health conditions and relationships can be influenced by depression. Zaptra is a combination medication that enhances mood by raising the level of chemical messengers in the brain. It also soothes the brain by reducing nerve cell activity that is excessive or abnormal. This medicine should not be taken without the consultation of a doctor. This medicine should be taken at the same time of the day with or without food and should not be skipped, even after the resolution of the symptoms. Zaptra has a habit-forming tendency, so it should not be abused. Even if you feel better, do not stop taking it until your doctor recommends you to. Sudden stoppage can lead to serious health issues.


Product Summary

Offer Price₹136.00
You Save₹24.00 (15% on MRP)
ContainsParoxetine(12.5 Mg) + Clonazepam(0.5 Mg)
Side effectsNausea, vomiting, diarrhoea, memory impairment, low energy, sexual dissatisfaction, constipation, headache, tremors, muscular hypotonia, abnormal bleeding, Insomnia and Anorexia.
Check more medicines with composition as Paroxetine(12.5 Mg) + Clonazepam(0.5 Mg)

Uses of Zaptra 12.5mg Strip Of 10 Tablets

  • Depression

Contraindications of Zaptra 12.5mg Strip Of 10 Tablets

  • If you are allergic to Zaptra tablets or their active ingredient.
  • If you consume alcohol regularly.
  • If you are pregnant or breastfeeding.
  • If you have suicidal tendencies.
  • If you have kidney disease.
  • If you have liver disease.
  • If you have a respiratory disease.
  • If you have sleep apnoea syndrome.
  • If you have narrow-angle glaucoma.
  • If you have cardiovascular diseases.
  • If you have bipolar disorders.
  • If you have diabetes mellitus.
  • If you have a history of bleeding disorders, bone fractures.
  • If you have seizure disorders.
  • Zaptra contraindicated in children.

Side effects of Zaptra 12.5mg Strip Of 10 Tablets

  • Nausea
  • Vomiting
  • Diarrhoea
  • Weak memory
  • Uncoordinated body movements
  • Drowsiness
  • Low sexual desire and delayed ejaculation
  • Tiredness
  • Anorgasmia
  • Constipation
  • Gastritis
  • Dry mouth
  • Fatigue
  • Headache
  • Tremors
  • Muscular hypotonia
  • Behavioural disturbances like aggressiveness, agitation
  • Increased or decreased appetite
  • Dyspepsia
  • Bleeding abnormalities
  • Bradycardia
  • Insomnia
  • Coordination disturbances
  • Anorexia
  • Angioedema
  • Hyponatraemia

Precautions and Warnings of Zaptra 12.5mg Strip Of 10 Tablets



Can I take Zaptra tablets during pregnancy?
Zaptra tablets may have potential side effects on the foetus and can be unsafe to use during pregnancy. Seek advice from an expert in cases of emergency. Limited studies on Zaptra tablets show defective effects on the foetus (teratogenic or embryocidal), so its safety for the foetus is questionable. Still, the doctor will check the benefit to risk ratio before prescribing it to the pregnant female.

Breast Feeding

Can I take Zaptra tablets while breastfeeding?
Zaptra tablets are not safe while breastfeeding as they pass through mother's milk in a significant amount, which can affect the baby. But you should closely monitor breastfed babies as not many studies have been done on the subject, and very limited information is available. The doctor will have to analyse the benefit to risk ratio before prescribing it to the lactating female.


Can I drive if I have taken Zaptra tablets ?
No. You should not drive while using Zaptra tablets as it decreases alertness. Zaptra tablets can cause drowsiness, dizziness, difficulty in concentration, fatigue. So, you should not perform activities that require mental alertness and physical strength, such as driving.


Can I consume alcohol with the Zaptra tablets ?
No. You should not consume alcohol with Zaptra tablets as it intensifies the effect of drowsiness, dizziness, difficulty in concentration, fatigue. It will affect daily activities that require attenti

Other General Warnings

Talk to your doctor if
  • You have to start other medications.
  • You notice an allergic reaction.
  • Your condition does not improve or worsen after taking the medication.
  • You want to stop the medication.
  • You are trying to conceive or breastfeeding the baby or on birth control pills.
  • You have been taking the tablets for a long time.
  • You are frequently missing doses.
  • You, by mistake, overdosed.
  • You notice a behavioural change or have suicidal thoughts.
  • Before the doctors prescribe this medication, share your medical history, as some of the diseases can make you more susceptible to some of the side effects or can intensify the effect of side effects.
  • It should not be given to children without consulting the doctors.
  • This medicine should not be skipped, even after the resolution of the symptoms.
  • This medicine should not be stopped abruptly. Suddenly stopping the medication can result in treatment failure or serious withdrawal symptoms, which may lead to serious health issues.

Mode of Action of Zaptra 12.5mg Strip Of 10 Tablets

How Does It Work?

Clonazepam in Zaptra raises gamma-amino-butyric acid (GABA) levels in the brain, a soothing chemical. Paroxetine raises serotonin levels, which improves mood, behaviour, and prevents depression sympto...
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Directions for Use of Zaptra 12.5mg Strip Of 10 Tablets

  • You should take Zaptra tablets in the same dose and duration prescribed by the doctor.
  • It should be swallowed as a whole with water.
  • It should not be chewed or crushed. Do not break the tablet.
  • You can take Zaptra tablets with or without food.
  • You should take it at a fixed time daily.
  • Avoid missing the dose or forgetting the dose.
  • It is advisable to take combutol with an antacid that contains aluminium at least four hours before or after taking medicine.

Interactions of Zaptra 12.5mg Strip Of 10 Tablets

Interactions with other medicines

  • Monoamine oxidase inhibitors: Rasagiline, linezolid, methylene blue
  • Tricyclic antidepressants: Clomipramine, nortriptyline, desipramine
  • Aspirin, Anticoagulants such as Warfarin
  • Phenothiazines: Perphenazine
  • Pimozide
  • Thioridazine
  • Increased risk of bleeding:
  • Pimozide
  • Atenolol
  • Metoprolol
  • Cimetidine
  • Diuretics
  • Anti-psychotics: Clozapine
  • Anxiolytics

Interactions with food items

  • Combining Zaptra tablets with alcohol is not advised, as it increases drowsiness and sedative effects. Alcohol shows additive Central Nervous System (CNS) depressant effects.

Storage and disposal of Zaptra 12.5mg Strip Of 10 Tablets

Store Zaptra tablets at room temperature, away from direct heat and light, in a cool place. Do not freeze it and keep them away from pets and children.

Dosage of Zaptra 12.5mg Strip Of 10 Tablets


Don't take Zaptra tablets more than the prescribed dose. Overdosing will not improve the symptoms; rather, it will lead to toxicity in the body. It can lead to severe side effects. In case of overdose...
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Missed a Dose

If you have missed the dose of Zaptra tablets, take it as soon as you remember it. If it is close to the time of the next dose, then let it be. Take the next dose at the normal time. Do not take two...
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Content Details


DR. Pallavi Kaushik

BDS & Masters in Clinical Research


Dr. Bhavika Shah

MBBS, MD (Dermatology), DNB (Dermatology)

Frequently Asked Questions (FAQs)


Q: I have observed that my symptoms have worsened after taking Zaptra tablets, so should I stop the tablet on my own?

A: No. You should not stop this medicine abruptly. It should be taken for the time as prescribed by the doctor. Suddenly stopping this medicine can result in treatment failure or the development of some serious side effects, which can lead to serious health issues, so it should be stopped only when the doctor suggests.

Q: How can I deal with weight gain associated with the use of Zaptra?

A: If you maintain healthy eating habits and exercise regularly, you may not gain weight. It's crucial to remember that preventing weight gain is easier than reducing weight.

Q: Are there any important precautions associated with the use of Zaptra tablets?

A: In the initial few months of treatment, the Zaptra tablets may cause suicidal thoughts or acts in patients. Suicidal thoughts and self-harm actions are common among patients with mood or behavioural disorders. Any changes in behaviour or mood should be noted and reported to your doctor. Make sure you go to the doctor for your follow-up appointments on time.
Product Details
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Last Updated on: 21 Jan 2022 | 10:36 AM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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