Uft Strip Of 28S 28 Capsules
28 Capsule(s) in StripMRP ₹5320.25
₹4072.21
23% OFF
Made by
WEST-COAST PHARMACEUTICAL WORKS LIMITED
Dosage
CAPSULE
Expiry
Product Summary
| Uses | Metastatic colorectal cancer |
| Therapy | Anti-neoplastic |
| Side effects | Diarrhea, nausea, vomiting, stomatitis, anorexia, fatigue, skin pigmentation changes, leukopenia |
Assurance
available
Regulated
Medical Description
Uft capsule contains a combination of active pharmaceutical ingredients: tegafur and uracil (often in a 1:4 ratio). It belongs to the fluoropyrimidine antimetabolite class.
Inside your body, tegafur is gradually converted into 5-fluorouracil (5-FU), an active chemotherapy drug that targets rapidly growing cancer cells. Uracil is added to inhibit the breakdown of 5-FU by dihydropyrimidine dehydrogenase (DPD) in your liver and tissues. By reducing 5-FU degradation, uracil allows higher, more consistent levels of the medicine to remain in your bloodstream, enhancing its antitumour activity when taken by mouth.
Uft capsule is used to manage colorectal cancer, particularly metastatic colorectal cancer, often in combination with calcium folinate (leucovorin).
Because Uft capsule can affect the bone marrow and gastrointestinal tract, an oncologist manages your treatment under strict supervision, with regular blood tests and health monitoring.
Uses
Contraindications
- If you have a known severe allergy or hypersensitivity to tegafur, uracil, 5-fluorouracil, or any ingredients in this medicine.
- If you have known complete dihydropyrimidine dehydrogenase (DPD) enzyme deficiency.
- If you have severe liver or kidney impairment.
- If you are currently taking, or have recently taken, antiviral medicines such as brivudine or sorivudine, or related medicines that strongly inhibit DPD.
- If you have severe, active infections or severely reduced bone marrow function before starting treatment.
- If you are pregnant or breastfeeding.
Side effects
- Low white blood cell count, risking infections
- Low red blood cell count (anemia), causing fatigue, pale skin, and weakness
- Low platelet count, leading to easy bruising or unexpected bleeding
- Diarrhea, nausea, vomiting, loss of appetite, and stomach cramps
- Inflammation or painful sores in the mouth, tongue, or lips (stomatitis/mucositis)
- General tiredness, weakness, and temporary hair thinning
- Darkening of the skin or nails (hyperpigmentation)
- Redness, swelling, or peeling on the palms of the hands and soles of the feet (Hand-Foot Syndrome)
- Dizziness, headache, or difficulty sleeping
- Dry skin, mild rash, or itching
- Changes in taste or dry mouth
- Severe Diarrhea: Having frequent, watery bowel movements that lead to severe dehydration, weakness, or dizziness.
- Severe Infections: High fever with shaking chills, sore throat, or burning during urination while your white blood cell count is low.
- Severe Mouth Sores: Painful ulcers or swelling in the mouth that prevent you from eating or drinking fluids.
- Unusual Bleeding: Frequent nosebleeds, bleeding gums, blood in vomit, or dark, tarry stools.
- Liver Problems: Yellowing of the eyes or skin (jaundice), dark urine, or severe upper right stomach pain.
Directions for Use
- Take Uft capsule strictly as prescribed by your doctor.
- Swallow the capsule whole with a full glass of water. Do not open, crush, or chew them.
- Wash your hands thoroughly before and after handling the capsule.
- Complete the full treatment cycle and rest periods exactly as your oncologist advises.
Storage and disposal
- Store the capsule at room temperature away from excessive heat, moisture, and direct sunlight.
- Keep the container tightly closed in its original packaging, out of reach of children and pets.
- Because this is a hazardous chemotherapy medicine, return any unused or expired capsule to your oncology clinic or pharmacist for safe biohazard disposal.
Quick Tips
- Keep all scheduled blood test appointments so your doctor can safely monitor your white blood cells, platelets, and liver function.
- Report any fever, severe diarrhea, painful mouth sores, or unusual bruising to your doctor immediately.
- Maintain good oral hygiene using a soft-bristled toothbrush to help prevent mouth ulcers.
- Apply moisturizer to your hands and feet to soothe treatment-related skin dryness.
- Both men and women must use effective birth control during treatment and for a prescribed period after the final dose.
Dosage
Overdose
Missed a Dose
How does this medicine work?
Interactions
Interactions with other medicines
- Antiviral Drugs: Medicines like sorivudine or brivudine are strictly contraindicated because they dangerously increase tegafur toxicity by inhibiting DPD and reducing 5-FU breakdown.
- Blood Thinners: Warfarin or other anticoagulants can significantly increase bleeding risk; closely monitor your clotting time (INR).
- Antiepileptic Drugs: May increase phenytoin blood levels and require dose adjustments.
- Folic Acid / Folinate: Calcium folinate enhances the activity and therapeutic effect of tegafur, but can also increase gastrointestinal side effects.
- Live Vaccines: Avoid live vaccines during treatment, as your weakened immune system may not respond safely.
Interactions with food items
- Uft capsule may be taken with or without food, depending on the specific product instructions.
- Drink plenty of fluids (water, clear broths) throughout the day to stay hydrated, especially if you experience mild diarrhea or nausea.
- Limit or avoid alcohol during treatment, especially if you have liver problems or significant treatment-related nausea.
Frequently Asked Questions (FAQs)
References:
- Central Drugs Standard Control Organisation (CDSCO). Approved List of Oncology and Cytotoxic Drugs. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India.
- Electronic Medicines Compendium (EMC). Tegafur/Uracil Capsules Summary of Product Characteristics (SmPC). London: Datapharm.
- European Medicines Agency (EMA). UFT (tegafur/uracil) European Public Assessment Report (EPAR). Amsterdam: EMA.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 5386: Tegafur. Bethesda, MD: National Library of Medicine; 2026.
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Manufacturer Details
Brand:UFT
Vendor Details
Fulfillment Information: Uft Capsule (28) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
In Case of Any Issues Contact Us
Email Id:care@pharmeasy.in
Phone Number:7666100300
Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703
Disclaimer
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