Pirazole S 40mg Tablets
Description
Pirazole S Tablet is used to treat acid reflux disease, stomach and intestinal ulcers, and to eradicate a bacteria known as H. Pylori to reduce the risk of intestinal ulcers. It is also used in treat
ing a condition called Zollinger-Ellison syndrome, characterised by excessive stomach acid production due to tumours in the pancreas. Pirazole S Tablet contains esomeprazole as the active ingredient. It works by lowering acid production in the stomach. Pirazole S Tablet should be taken in doses and for a duration as advised by the doctor or pharmacist. It is preferably taken on an empty stomach, one hour before a meal. Before using this medicine, inform the doctor of your complete medical history.
Product Summary
Offer Price | ₹33.44 |
You Save | ₹10.56 (24% on MRP) |
Contains | Esomeprazole(40.0 Mg) |
Uses | GERD, stomach ulcers, acidity |
Side effects | Headache, dizziness, nausea, stomach pain, bloating |
Therapy | ANTACID |
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Uses of Pirazole S 40 MG
- For the treatment of ulcers in the stomach and intestine.
- Provides relief from heartburn, pain and chest pain due to acid reflux disease (Gastroesophageal reflux disease).
- To treat Zollinger-Ellison syndrome, a condition of increased acid production in the stomach due to a tumour.
- It helps to eradicate infection of the bacteria H. Pylori, which if left untreated, can cause ulcers.
Contraindications of Pirazole S 40 MG
- If you are allergic to Esomeprazole or any other ingredients of Pirazole S Tablet.
- If you are taking an anti-HIV medicine - Nelfinavir.
Side effects of Pirazole S 40 MG
- Headache
- Dizziness
- Nausea
- Stomach pain
- Bloating
- Diarrhoea
- Constipation
- Dry mouth
Precautions and Warnings of Pirazole S 40 MG
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You are undergoing long term treatment of this medicine.
- You are using anti-HIV medicines like Atazanavir or Nelfinavir.
- You develop stomach infections after using Pirazole S Tablets.
- You have unexplained weight loss, frequent vomiting, difficulty in swallowing and blood vomitings.
- You are an elderly patient on a long term therapy. It increases the risk of fracture of hip, wrist and spine bones.
- You have a vitamin B12 deficiency. The use of this medicine can result in very low levels of Vitamin B12 in prolonged therapy.
- You are undergoing treatment for a bacterial infection caused by H. pylori and are using an antibiotic called Clarithromycin.
- You have a skin disorder, Subacute cutaneous lupus erythematosus, characterised by a rash on areas of skin exposed to the sun.
- You have a magnesium deficiency. It can result in very low levels of magnesium characterised by weakness, fits and irregular heartbeat.
Mode of Action of Pirazole S 40 MG
How Does It Work?
Directions for Use of Pirazole S 40 MG
- Pirazole S Tablets should be taken as directed by your doctor.
- It should be taken on an empty stomach.
- It would be best if you took it at a fixed time for optimal results.
- You should not consume it more than recommended by the doctor.
Interactions of Pirazole S 40 MG
Interactions with other medicines
- Certain medicines can affect the way Pirazole S Tablet works or Pirazole S Tablet itself can affect the action of other medicines taken at the same time.
- Concomitant use of Digoxin, a medicine used to treat heart failure with Pirazole S Tablet increases the effect of Digoxin and may result in toxicity.
- The use of anti-HIV medicines like Atazanavir and Nelfinavir with this medicine can decrease the effect of anti-HIV medicines.
- Pirazole S mg can increase the effect of Phenytoin, a medicine used to control fits, Voriconazole (antifungal) and Diazepam, a medicine used for a psychiatric disorder.
- The blood-thinning action of Warfarin is increased when used together with Pirazole S mg and there is a risk of bleeding.
- Other medicines such as Cisapride (used for constipation), Clopidogrel & Cliostazal (Blood thinner), Tacrolimus and Methotrexate (Immunosuppressants) should be used cautiously with Pirazole S Tablets.
- You should always tell the doctor if you are taking any other medicines, herbal preparation and supplements to avoid any interaction.
Storage and disposal of Pirazole S 40 MG
- Pirazole S Tablets should be stored in a cool and dry place.
- Keep it out of reach of children and pets.
Dosage of Pirazole S 40 MG
Overdose
Missed a Dose
Content Details

Dr. Mansi Savla
B. Pharm, PharmD

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Can I take Pirazole S after food??
Q: Does Pirazole S Tablet help in reducing gas?
Q: Is Pirazole S an antibiotic medicine?
References
- Esomeprazole 40 mg Gastro-resistant Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 24 March 2025]
- Emazole 40 mg Gastro-Resistant Tablets [Internet]. Hpra.ie. 2025 [cited 24 March 2025]
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 24 March 2025]
- Zamani NF, Sjahid AS, Tuan Kamauzaman TH, Lee YY, Islam MA. Efficacy and Safety of Domperidone in Combination with Proton Pump Inhibitors in Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. J Clin Med. 2022 Sep 7;11(18):5268. doi: 10.3390/jcm11185268. PMID: 36142915; PMCID: PMC9505562.[cited 27 Feb 2025]
- NHS.uk. About Domperidone [Internet]. [cited 27 Feb 2025].
- DrugBank. Domperidone [Internet]. [cited 27 Feb 2025].
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 9568614, Esomeprazole. [cited 27 Feb 2025]
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