Naxdom 500mg Strip Of 10 Tablets
Description
Naxdom 500 Tablet is a medication commonly used to treat joint pain and swelling associated with conditions such as arthritis and rheumatoid arthritis. It is also helpful in preventing and treating migraine headaches. The tablet contains two active ingredients: naproxen, which reduces pain and inflammation, and domperidone, which helps prevent nausea and stomach discomfort.
This medicine works by blocking certain chemicals in the body that cause inflammation and pain. Naproxen targets the pain and swelling, while domperidone helps manage any stomach issues that may occur due to the pain medicine. Together, they provide relief from both pain and potential side effects, such as nausea.
Naxdom 500 Tablet should always be taken as prescribed by your doctor. It is important to take the tablet with food to avoid stomach upset. Do not change the dose or stop taking it without consulting your doctor, even if you start to feel better.
Other medicines such as Napra D 500mg tablet, Naprosyn D 500 tablet, and Macprox DP 500mg tablet also contain naproxen and domperidone. These work in a similar way but should only be taken if recommended by your doctor.
Before starting Naxdom 500 Tablet, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Additionally, please share your complete medical history and list all other medications you are currently taking. Some people may experience side effects like dizziness, drowsiness, headache, or dry mouth. If any side effect bothers you or don’t go away, let your doctor know right away.
Product Summary
Offer Price | ₹124.96 |
You Save | ₹17.04 (12% on MRP) |
Contains | Domperidone(10.0 Mg)+Naproxen(500.0 Mg) |
Uses | Migraine, headache, arthritis pain and swelling |
Side effects | Dry mouth, headache, confusion, dizziness, fatigue |
Therapy | MIGRAINE DRUGS |
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Uses
Contraindications
- If you are allergic to Naproxen, Domperidone or any other ingredients of this medicine.
- If you have stomach or intestinal ulcers, bleeding from ulcers.
- If you have a history of ulcers or bleeding previously.
- If you have an allergy to painkillers like aspirin or ibuprofen.
- If you have any problems with your heart, liver and kidney.
- If you have a pituitary gland tumour which releases an excess of prolactin hormone (prolactinoma).
- If you have an obstruction, blockage or perforation (tear) in the intestine or in any part of the gut
- If you have any condition due to which there is a salt imbalance in your body (low levels of potassium or magnesium or high levels of potassium).
- If you're pregnant or think you may be pregnant or breastfeeding.
Side effects
- Dry mouth
- Headache
- Confusion
- Dizziness
- Fatigue
- Drowsiness
- Rashes & itching
- Swelling
- Palpitations
- Ringing in the ear
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You are using other medicines or NSAIDs that may cause bleeding and ulcers in the stomach.
- You have any other stomach and intestinal diseases.
- You smoke or consume alcohol regularly.
- You are above 65 years of age.
- You had or have problems with your heart, liver or kidney.
- You have diabetes, high blood pressure, or cholesterol.
- You have asthma or any problems with your breathing.
- You are planning to have a baby, as Naproxen may interfere with female fertility.
- You have to undergo any blood or urine tests.
- You are taking medicines or painkillers for headaches too often.
- You are taking Apomorphine.
- You have developed an allergy or skin rash after taking this medicine.
- You have an autoimmune disorder called systemic lupus erythematosus or any tissue disorder or blood clotting issues.
Directions for Use
- Take Naxdom 500 mg tablet as a whole with a sufficient amount of water.
- You should take this medicine regularly, at the same time and without fail as directed by your doctor.
- You should not consume it more than that prescribed by your doctor.
Storage and disposal
- Store Naxdom 500 mg tablet below 25°C protected from moisture, sunlight and heat.
- Keep this medicine away from children and pets.
- Do not flush the expired medicine in the toilet or throw them in household waste or drain.
Quick Tips
- It is important to take Naxdom 500 tablets with meals to avoid stomach upset. Always take this medicine as prescribed by your doctor and do not exceed the prescribed dose.
- Before taking Naxdom 500, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, and also provide information about all your medications and medical history.
- Naxdom 500 tablets may cause dizziness, depression, sleepiness, fatigue, or difficulty sleeping. It may also affect your vision, so it is important to be cautious while driving.
- Individuals with kidney disease should use Naxdom 500 tablets with caution. Make sure to talk to your doctor if you have a history of alcoholism.
- Long-term use of Naxdom 500 tablets can harm the liver and kidneys.
- This medication can aggravate the symptoms of Parkinson’s disease, asthma, colitis, and Crohn's disease, so it should be used with caution. It should not be used in children below 5 years of age.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- You may experience abnormal heart rhythm when taking Naxdom 500 tablet along with medicines like Amiodarone, used in abnormal heart rhythm, Haloperidol and Escitalopram used in psychiatric illness, antibiotics such as Erythromycin, antifungal such as Ketoconazole and Lumefantrine used in malaria, Cisapride used for gastric problems, Mizolastine used in allergy and anticancer such as Vandetanib....
- Concomitant use of this medicine along with Diltiazem, and Verapamil used for the treatment of heart problems is not recommended.
- Naxdom 500 tablet decreases the effectiveness of Atenolol and water pills such as Furosemide used to treat high blood pressure.
- Maintain a minimum gap of 10-12 days between the use of Naxdom 500 and mifepristone as the former can reduce the effectiveness of the latter.
- The chances of kidney damage increase if Naxdom 500 tablet is taken along with immunosuppressive medicine such as Cyclosporine and Tacrolimus.
- The chances of stomach ulcers and bleeding increase if used along with steroids like prednisone, painkillers, and blood thinners like Warfarin and Bisphosphonates used to treat weakened bone.
- You may experience fits and convulsions if taken along with antibiotics such as Ciprofloxacin and Ofloxacin.
- The side effects related to blood increase if taken along with Zidovudine used in the treatment of HIV infection.
- You should take Naxdom 500 tablets at least 1 hour before or 4 to 6 hours after Cholestyramine is used in the treatment of cholesterol problems.
- Other medicines like Phenytoin, Lithium, Methotrexate, Digoxin Probenecid, Gliclazide and Sulfamethoxazole should be used cautiously.
- Discuss with your doctor any other medicine, herbal preparation and supplements you are taking currently to avoid any possible drug interactions.
Interactions with food items
Content Details

Dr. Arpit Verma
MBBS, MD, CCEBDM Diabetology

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Naxdom 500 vs Vasograin, which one is better for migraine?
Q: Naxdom 500 vs Headset, are they the same?
Q: I am having a heart problem, can I take Naxdom 500 mg Tablet?
Q: Can Naxdom 500 tablet be taken empty stomach?
Q: Can I take Naxdom 500 mg tablets with other painkillers?
Q: How frequently can we take Naxdom 500 medicine?
Q: Can Dolo 650 and Naxdom 500 be taken together?
Q: Does Naxdom 500 tablet affect kidneys?
Q: Can I take Naxdom 500 mg tablets for headaches?
Q: Can I take higher than the recommended dose of Naxdom 500 tablet?
Q: Can I take Naxdom 500 daily?
Q: Can I stop taking Naxdom 500 if I feel an improvement in my condition?
Q: Can Naxdom 500 tablet cause constipation?
Q: How long will Naxdom 500 take to work?
Q: What is Naxdom 500 used for?
Q: Is Naxdom 500 good for migraine?
Q: Does Naxdom 500 Tablet make you sleepy?
Q: Is Naxdom 500 and naproxen same?
Q: Naxdom 500 vs Rizact 10 tablet, what are the differences?
References
- Motilium Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 21 December 2021]
- Naproxen Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 21 December 2021]
- Motilium Film-coated Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 21 December 2021]
- Drugs.com. Domperidone: Uses, Dosage, Side Effects, Warnings. Drugs.com. 2024 [cited 20 December 2024]
- Drugs.com. Naproxen: Uses, Dosage, Side Effects, Warnings [Internet]. Drugs.com; 2024 [cited 20 December 2024]
- EC-NAPROSYN® (naproxen delayed-release tablets) U.S. Food and Drug Administration. Prescribing information: Silver Spring, MD: Food and Drug Administration; 2024 [cited 20 December 2024]
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