Metorex 50mg Injection 2ml
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Metorex 50 MG Description
Metorex Injection has varied used based on conditions such as 'Immunosuppressant action' against psoriasis and rheumatoid arthritis while 'Anti-neoplastic' action against various types of cancer. It contains methotrexate as its active ingredient. It acts by suppressing the immune response, reducing the swelling, stiffness and inflammation along with slowing down the skin proliferation in rheumatoid arthritis and psoriasis respectively, whereas it inhibits or slows down the growth of cancerous cells in various types of cancer. Metorex Injection is given under the medical supervision of a doctor or nurse at the hospital or clinic setup. It should not be consumed orally. It should not be used in pregnant and breastfeeding women. Inform your doctor about all the medical conditions and medication you have or had....
|You Save||₹7.20 (15% on MRP)|
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|Uses||Psorasis, Rheumatoid arthritis, Cancer|
|Side effects||Diarrhoea, Ulcer, Weakness, Cough|
Check more medicines with composition as Methotrexate(50.0 Mg)
Uses of Metorex 50 MG
Metorex Injection is used to treat varied conditions such as psoriasis, rheumatoid arthritis and various types of cancers such as breast and lung cancers.
Contraindications of Metorex 50 MG
- If you are allergic to Methotrexate or any other component of Metorex Injection.
- If you are pregnant and breastfeeding.
- If you have severe liver or kidney disease.
- If you have pre-existing blood disorders such as decreased platelets and white blood cells.
Side effects of Metorex 50 MG
- Mouth ulcers
- Menstrual problems
- Skin rashes
- Persistent cough
- Pain in joints, muscles and stomach
- Swelling of feet
- Yellowing of the skin (an indication of liver damage)
- Fever with chills
- Unusual bleeding
- Blurred vision
- Temporary hair loss
- Loss of appetite
- Difficulty in passing urine
- Nausea or vomiting
- Decrease white blood cells
Precautions and Warnings of Metorex 50 MG
Can Metorex Injection be administered during pregnancy?
Metorex Injection is not recommended during pregnancy as it can lead to threatened pregnancy along with causing serious harm to the unborn baby. Women of childbearing age should strictly use contraception and avoid pregnancy during its administration period. Inform your doctor if you are pregnant, think you may be pregnant or planning a pregnancy.
Can Metorex Injection be taken during breastfeeding?
Metorex Injection should not be administered during breastfeeding as it can cause harm to the newborn baby. Inform your doctor if you are a nursing mother.
Can I drive after the administration of Metorex Injection?
Do not drive until your vision is clear as the administration of Metorex Injection may cause dizziness and drowsiness.
Can I consume alcohol after the administration of Metorex Injection?
Alcohol should not be consumed with Metorex Injection, as it can increase the side effect. Inform your doctor if you consume it often.
Other General Warnings
Talk to your doctor if
- You have liver, kidney or bone marrow disease.
- You are pregnant or planning pregnancy and breastfeeding.
- You have any known medical condition.
- You are on any other medication or therapy.
- You have stomach-intestinal or lung disease or conditions such as ulcers, persistent cough.
- You have taken any vaccination recently (live vaccine).
- You experience any skin reaction or other side effect after taking this medicine.
- Metorex Injection should not be used in children below 3 years of age.
Mode of Action of Metorex 50 MG
How Does It Work?
The composition of Metorex Injection works by stopping or slowing down the growth of cancer cells and suppressing the immune system. In patients with rheumatoid arthritis, it reduces the activity of the body's immune system. This decreases swelling, pain and stiffness, ultimately improving the function of joints. It also slows down the proliferation of infected skin cells....
Directions for Use of Metorex 50 MG
- Metorex Injection will be given by a doctor or nurse in a hospital/clinic.
- Do not self-inject. Follow any aftercare instructions given by the doctor/nurse.
Interactions of Metorex 50 MG
Interactions with other medicines
- Some medicines can affect the way Metorex Injection works or the Metorex itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
- Especially, if you are taking painkiller medicines to provide relief from pain such as aceclofenac, ibuprofen, diclofenac or other immunomodulatory medicines such as cyclosporine.
- When the Metorex Injection is administered during the period of radiotherapy, it may increase the risk of cell death in soft tissues and bones.
- If you have recently take any live vaccines, this medicine may alter the effectiveness of medicine.
Storage and disposal of Metorex 50 MG
- Store Metorex Injection at a temperature not exceeding 30 °C in the original package to protect from light. Do not freeze.
- Expired or unused medication should be disposed of via proper waste management protocol suggested by a pharmacist.
Dosage of Metorex 50 MG
- The overdose of Metorex Injection can cause vomiting, diarrhoea and gastrointestinal bleeding, severe bone marrow suppression, liver toxicity (more likely in patients with pre-existing risk factors for liver disease), sudden shortness of breath and a dry, persistent cough, and fever. A single overdose has also shown a fatal side effect. Another cause of death is bone marrow suppression....
- Several deaths have been reported all over the world from methotrexate overdose because of accidentally taking the injection daily instead of once a week dose as prescribed.
- This injection will be given by a doctor or nurse. Thus, the chances of overdose are unlikely. However, if you experience any discomfort or specific symptoms, inform your doctor or reach out to the nearest hospital....
Missed a Dose
It is unlikely that the dose of this injection will be missed if you are monitored in a healthcare set up. However, if you have missed taking any dose of this injection, inform your doctor or nurse immediately....
Frequently Asked Questions (FAQs)
Q: What precautions should I take before treatment with Metorex?
A: The use of the medicine for a prolonged duration may cause liver damage, including cirrhosis (irreversible scarring of the liver), which may be fatal. High doses of this injection can also damage the kidneys and cause their failure. This injection may not be suitable for individuals with psoriasis or rheumatoid arthritis if they: are alcoholics, have alcoholic liver disease or other chronic liver diseases; have an immunodeficiency syndrome; and have a blood deficiency disorder, such as low red blood cell counts, low white blood counts and low blood platelet counts.
Q: Can Metorex cause weight gain?
A: The side effects of Metorex Injection are nausea, diarrhoea and an upset stomach, which may cause loss of weight.
Q: Is Metorex Injection a steroid?
A: No, Metorex Injection is not a steroid. It is an immunosuppressant and anti-neoplastic medicine.
Q: Can this medicine cause infections?
A: This medicine is known to affect the immune system that can lead to some serious infections. Consult your doctor for more details about the same.
Q: What precaution should be taken if the expired dosage of Metorex is administered?
A: The administration of this injection is limited to a healthcare professional only. However, if expired injection has been administered to you, you should consult your doctor immediately.
- IMUTREX Tablets / Injection [Internet]. CiplaMed. 2021 [cited 11 May 2022]
- Methotrexate 100 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 11 May 2022]
- Methotrexate 100 mg/ml Injection - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 11 May 2022]
- CDSCO [Internet]. Cdscoonline.gov.in. 2021 [cited 11 May 2022]
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