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Lithic Sr 400mg Tablet

Lithic Sr 400mg Tablet

10 Tablet(s) in Strip
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Lithic Sr 400 MG Description

Lithic SR is a prescription medication. The active component of this medication is Lithium. Lithium is a mood stabiliser primarily used to treat Mania and Bipolar Disorder. Mania is a mental health

disorder characterised by pervasive elevation of mood and activity. Mania can present with symptoms like excessive happiness or irritability, increased activity, excessive speech, decreased need for sleep, increased self-esteem and can even progress to delusions and hallucinations. Mania can have multiple causes and can also be a presentation of bipolar disorder. Bipolar disorder (BPAD) is characterised by periods of depression and mania interspersed by the absence of symptoms. While the exact mechanism of BPAD is still under study, research has shown abnormalities in areas of the brain associated with cognition and processing emotions. Multiple chemical messengers like dopamine, serotonin, and BDNF (brain-derived neurotrophic factors) are indicated in manic and depressive phases. Treatment with Lithium requires close monitoring and follow-up. The improper use of this medication can result in adverse health effects that can be serious.


Product Summary

Offer Price₹44.72
You Save₹7.28 (14% on MRP)
ContainsLithium(400.0 Mg)
UsesTreatment of Bipolar Disorder, Mania and Depression Associated With Mania.
Side effectsTremors, Acne, Weight gain, Nausea, Diarrhoea, Dry mouth, Increased thirst.
Check more medicines with composition as Lithium(400.0 Mg)

Uses of Lithic Sr 400 MG

  • Treatment of Bipolar Disorder
  • Treatment of Mania
  • Treatment Depression associated with mania

Contraindications of Lithic Sr 400 MG

  • This medication is contraindicated in patients with
  • Hypersensitivity to Lithium or any other components in this medication.
  • Addison's disease – a condition where the adrenal glands do not produce sufficient amounts of hormones like cortisol and aldosterone.
  • Brugada syndrome – It is characterised by abnormal cardiac rhythms and risk of sudden death.
  • Decreased sodium levels (hyponatremia).
  • Hypothyroidism (low thyroid levels).
  • Cardiac disorders
  • Kidney failure
  • Pregnancy
  • Children < 12 years of age
  • Prior to surgical/ dental procedures requiring anaesthesia (needs to be stopped at least 24-48 hours prior to procedure).
  • To use high amounts of caution in patients with
  • Glaucoma
  • Known seizure disorder
  • Liver dysfunction
  • Kidney dysfunction
  • Heart disorders

Side effects of Lithic Sr 400 MG

  • Tremors
  • Acne
  • Weight gain
  • Dry mouth
  • Increased thirst
  • Increased frequency of urination
  • Fatigue
  • Hair loss
  • Alteration of blood cell counts (often an increase in white blood cell counts)
  • Nausea
  • Diarrhoea
  • Confusion
  • Slurring of speech
  • Tremors
  • Memory impairment

Precautions and Warnings of Lithic Sr 400 MG



Can I take Lithic SR during pregnancy?
Lithium is contraindicated in pregnancy as it can cause fetal abnormalities. It is a category D medication. It is not recommended before or during pregnancy. Inform your doctor about your health condition or your intention to conceive at the time of prescription of Lithium.

Breast Feeding

Can I take Lithic SR while breastfeeding?
This medication is not recommended during breastfeeding. Lithium is excreted in breast milk and may cause harm to the infant. Talk to your doctor for more information.


Can I drive if I have taken Lithic SR?
Driving and use of heavy machinery while using this medication are not recommended as it causes confusion, blurring of vision, and decreased motor control.


Can I consume alcohol with the Lithic SR?
Consuming alcohol with this medication can cause serious side effects and is strictly contraindicated.

Other General Warnings

Talk to your doctor if
  • You are taking Lithium if you have any illness (like a fever, gastrointestinal distress, UTI, etc.).
  • You’ve a history of seizures or are taking any medications known to decrease seizure potential.
  • You witness sudden changes in mood or worsening of symptoms of schizophrenia.
  • You are on any other medications you take alongside Lithic SR to rule out any debilitating medicine interactions.

Mode of Action of Lithic Sr 400 MG

How Does It Work?

Lithium is a Mood Stabiliser. The exact mechanism of action is unknown. Studies show that Lithium affects the transmission of certain chemical messengers in the brain like serotonin, nor-epinephrine a...
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Directions for Use of Lithic Sr 400 MG

  • Lithic SR should be taken as prescribed by the treating physician.
  • It’s recommended to take this medication on a regular schedule at the same time every day for best results.
  • Swallow Lithic SR as a whole. Don’t crush, chew or break this tablet.
  • This medication can take between 1 to 3 weeks for symptoms of mania to resolve.
  • Finish the full course of this medication as prescribed by your treating doctor. Abrupt stoppage of the medication can cause withdrawal side effects. Consult your doctor before stopping this medicatio...
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Interactions of Lithic Sr 400 MG

Interactions with other medicines

  • The concomitant use with certain medications can decrease the amount of lithium excreted from the body, resulting in its accumulation and toxicity. These medications include
  • Diuretics - Furosemide, Bendroflumethiazide
  • ACE(Angiotensin-converting-enzyme) Inhibitors - Enalapril, Lisinopril, Ramipril, etc.
  • ARBs (Angiotensin II receptor blocker) -Telmisartan, Losartan, etc.
  • NSAIDS (Non-steroidal anti-inflammatory drugs) - Aspirin, Ibuprofen, Etoricoxib, etc.
  • Antidepressants -Fluvoxamine, Paroxetine or Fluoxetine.
  • Antibiotics - Trimethoprim, Metronidazole.
  • Administration with medicines acting on the CNS like Phenytoin, Carbamazepine, etc., is not recommended as it can increase the severity of CNS side effects.
  • Lithium can decrease the seizure threshold; hence, concomitant use with other medications with a similar property is contraindicated, especially in people with epilepsy.
  • Lithium should not be used with other medications that cause cardiac rhythm irregularities.

Interactions with food items

  • Avoid a low salt diet and drink plenty of water while on this medication. Limit consumption of caffeine-containing substances such as tea, coffee etc. while on this medication.
  • Maintain a healthy diet and exercise regularly as lithium causes weight gain.
  • Taking this medication with food can decrease gastrointestinal distress.

Storage and disposal of Lithic Sr 400 MG

Store Lithic SR in a cool and dry place away from direct light and moisture. Do not use the medicine after the date of expiration. Keep the Lithic SR tablets away from children and pets. Don’t flush t...
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Dosage of Lithic Sr 400 MG


An overdose of Lithic SR can lead to many serious side effects. The most common symptoms are excessive sleepiness (somnolence), blurred vision, seizures, and may progress to coma. In case of a suspect...
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Missed a Dose

If you miss a dose of Lithic SR, take it as soon as possible. If the duration missed is too long, and it’s almost time for the next dose, skip the missed dose. Don’t double the dose of the tablet.

Content Details


Dr. Bhavika Shah

MBBS, MD (Dermatology), DNB (Dermatology)

Frequently Asked Questions (FAQs)


Q: It has been a few days since I have started using Lithic SR, but I do not see any effects. Should I increase the dose?

A: Lithic SR can usually be efficacious within one week of usage but can take up to 3 weeks or more in patients for optimal effects. It is important to take this medication only at the dose and for the full duration prescribed by your treating physician. Changing the dose of Lithium without careful supervision can cause dangerous side effects.

Q: I want to stop taking Lithic SR. What should I do?

A: To stop this Lithic SR, consult your doctor. They’ll gradually taper the dose and stop it appropriately. Sudden stoppage of this medication can cause recurrence of symptoms and withdrawal side-effects.

Q: I started Lithic SR 2 weeks back. I suddenly started feeling very nauseous. What do I do?

A: Nausea is a common side effect of Lithic SR. However, sudden symptoms can indicate an increase in blood levels of the medication. Consult your doctor immediately to know how to manage these symptoms.
Product Details
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Last Updated on: 24 Mar 2022 | 09:40 PM (IST)

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