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Duzela M 20mg Strip Of 10 Capsules

10 Capsule(s) in Strip
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Duzela M 20mg Strip Of 10 Capsules Description

Duzela M tablet is a prescription medicine used for treating depression, urinary incontinence, and neuropathic (nerve) pain related to diabetes. It is composed of Duloxetine and methylcobalamin or vi

tamin B12 as its main ingredients. Duloxetine belongs to a class of medicines called antidepressants. Mode of action of the Duzela M capsule is to increase the levels of specific chemical messengers, which regulates the mood and lower the pain caused by nerve damage. Duzela M capsules help in managing the symptoms of depression, especially in people who are not responding to other medications. It works by decreasing restlessness, stress, fear, irritability, loss of interest, etc. This capsule also has methylcobalamin (vitamin B 12), which repairs damaged nerves and protects them from further damage, especially in diabetic patients. You should take Duzela M capsule exactly as prescribed by a doctor, as it induces sleeplessness, constipation, low sex desire, etc. Most of these side effects of Duzela M capsule do not need medical treatment but consult your doctor if they persist. It should also be used with caution, as it tends to cause mood changes and suicidal thoughts.


Product Summary

Offer Price₹112.20
You Save₹19.80 (15% on MRP)
ContainsVitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin(1.5 Mg) + Duloxetine(20.0 Mg)
UsesAnxiety disorder, nerve pain, stress urinary incontinence
Side effectsDrowsiness, nausea, headache, dizziness, constipation, loss of appetites, dry mouth, increased sweating, insomnia, low blood pressure, blurred vision, heartburn, changes in sexual drive
Check more medicines with composition as Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin(1.5 Mg) + Duloxetine(20.0 Mg)

Uses of Duzela M 20mg Strip Of 10 Capsules

  • According to CDSCO, the Duzela M capsule can be used for the following conditions.
  • It is used in the treatment of major depressive disorders in adults only,
  • It is used in managing moderate to severe stress urinary incontinence (lack of control over urination) in women.
  • It is also used in the management of neuropathic pain in diabetic peripheral neuropathy (nerve damage due to diabetes).

Contraindications of Duzela M 20mg Strip Of 10 Capsules

  • If you have an allergic reaction to any ingrident of the Duzela M capsule
  • If you have uncontrolled hypertension
  • If you have narrow-angle glaucoma (an eye condition, it causes an increase in fluid pressure inside the eye and worsens the situation)
  • If you have any self-harming or suicidal thoughts
  • If you are already taking different antidepressants
  • If you have a severe renal condition
  • If you have any bleeding disorders
  • If you have severe skin conditions

Side effects of Duzela M 20mg Strip Of 10 Capsules

  • Nausea
  • Difficulty in sleeping
  • Drowsiness
  • Excessive sweating
  • Blurred vision
  • Burning sensation on soles and palms
  • Sexual problems like erectile dysfunction, low sex desire, etc.
  • Suicidal thoughts

Precautions and Warnings of Duzela M 20mg Strip Of 10 Capsules



Can I take a Duzela M tablet during pregnancy?
Duzela M is not recommended for pregnant women unless necessary and only if the doctor prescribes it. There is a limited data available with regards to the safety during the pregnancy; animal studies have shown adverse effects on the baby. Inform your doctor if you get pregnant while on treatment with the medication.

Breast Feeding

Can I take a Duzela M tablet while breastfeeding?
There is not much information on Duzela M capsule’s safety in breastfeeding women and babies. If you are breastfeeding, then consult your doctor before taking this medication, to prevent any effects on the newborn baby.


Can I drive if I have taken the Duzela M capsule?
It is not safe to drive after taking the Duzela M Capsule. It causes side effects like drowsiness, double vision, dizziness, and blurred vision. It is also not safe to operate heavy machinery after taking this medication.


Can I consume alcohol with the Duzela M Capsule?
Duzela M capsule exaggerates the effects of alcohol. It also causes nausea, vomiting, sleepiness, dizziness, fainting, diminished reflexes, and blurred vision. It is not advisable to take this medicine with alcohol.

Other General Warnings

Talk to your doctor if
  • You are using any herbal medicines or supplements which can interfere with this medicine and cause adverse effects
  • You experience a change or drop in blood glucose levels with Duzela M medicine
  • You are an elderly person over the age of 65. You should monitor Duzela M capsule dose as the side effects are high due to slow metabolism
  • You notice frequent fluctuation in your blood pressure. Duzela M capsule can cause low pressure when you stand up suddenly (orthostatic hypotension)

Mode of Action of Duzela M 20mg Strip Of 10 Capsules

How Does It Work?

Duzela M capsule contains duloxetine and methylcobalamin (vitamin B12). Duloxetine is an antidepressant and it works by increasing the levels of serotonin and noradrenaline, the chemical messengers th...
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Directions for Use of Duzela M 20mg Strip Of 10 Capsules

  • Take the Duzela M tablet precisely in the dosage and duration prescribed by the doctor
  • Do not exceed the dose of this medicine, even if you cannot feel its effects
  • Do not break the Duzela M capsule or chew itTake Duzela M as a whole with a glass of water
  • Try not to use it with other medications without informing your doctor
  • Do not take this capsule, if the package has been already opened

Interactions of Duzela M 20mg Strip Of 10 Capsules

Interactions with other medicines

  • If you take other antidepressant medications like diazepam,linezolid, fluoxetine, etc., with Duzela M medicine. It can cause severe reactions
  • If you are on blood thinners like aspirin, warfarin, etc., taking them with a Duzela M tablet can increase the risk of abnormal bleeding
  • If you are using other medications like sertraline, lithium, and dextromethorphan. They can cause severe side effects
  • Try not to take high doses of opioid painkillers like tramadol with Duzela M medicine without confirming with your doctor; it can cause extreme drowsiness and side effects
  • Do not try to mix antibiotics like ciprofloxacin; it increases the level of Duzela M in the blood and can cause serious side effects

Interactions with food items

  • Some brain-stimulating drinks like coffee, cola, energy drinks, etc., interfere with the effects of Duzela M medicine.
  • Try to avoid grapefruit and its juice, as it decreases the effects of Duzela M medicine.

Storage and disposal of Duzela M 20mg Strip Of 10 Capsules

Try to store Duzela M tablets in dry conditions at room temperature. Keep Duzela M tablets away from children and pets. Also, Keep them away from wet surfaces, direct sunlight, and humid conditions. D...
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Dosage of Duzela M 20mg Strip Of 10 Capsules


Overdose on Duzela M capsule can cause sleepiness, lightheadedness, nausea, vomiting, increased heart rate, seizures, fainting, low blood pressure, and loss of consciousness. If you overdose on Duzela...
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Missed a Dose

If you have missed a single dose of Duzela M tablet, take it as soon as you remember. If you recall missing a dose when it's almost the time to take the next dose, skip the missed one and continue wit...
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Content Details


Dr. Vijay Y

MBBS, MD in Clinical Pharmacology

Frequently Asked Questions (FAQs)


Q: Can I give the Duzela M capsule to the children below 18 years of age?

A: No, do not give it to children unless your doctor recommends it. Duzela M capsule is not recommended for children below seven years of age. It tends to cause suicidal thoughts in children and adolescents, so the dose should be monitored.

Q: Would I be addicted to the Duzela M capsule if I took it every day?

A: No, the Duzela M capsule is not a habit-forming medicine and does not cause addiction. But do not stop using it suddenly without informing your doctor, as it can cause withdrawal symptoms like muscle tremors, sweating, dizziness, etc.

Q: Should I take the Duzela M capsule with food or without consuming food?

A: You can take a Duzela M capsule with or without consuming a meal. But try to have it at the same time each day to maintain the stable levels of this medicine in the body.
Product Details
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Last Updated on: 28 Feb 2022 | 09:37 AM (IST)
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