Dukinase 50000Iu Injection

• Dukinase powder for injection is used to clear blood clots that block tubes (catheters or cannulas) placed in your veins or arteries.
• It helps treat serious blood clots in the deep veins, usually in the legs, a condition known as deep vein thrombosis (DVT).
• It is used in emergencies to treat a large blood clot in the lungs, also called a pulmonary embolism, which can be very dangerous.
• It is also used to treat blocked blood flow in the arms or legs, when a clot is cutting off circulation and may put the limb at risk of damage.

• If you are allergic to urokinase or any other ingredients of Dukinase powder for injection.
• If you have active or recent serious bleeding, such as in the stomach, intestines, or brain, or if you have had major surgery, injury, or childbirth recently.
• If you have had a recent stroke or brain-related bleeding (within the last 2 months).
• If you have severe, uncontrolled high blood pressure.
• If you have serious liver or kidney problems, unless you are on dialysis.
• If you have a blood clotting disorder, a very low platelet count, or conditions such as an aneurysm or abnormal blood vessel connections.
• If you have certain serious infections or inflammations, such as pancreatitis, heart infections, or sepsis.
• If you have tumours that could easily bleed, especially in the brain.

• Bleeding
• Nosebleeds (epistaxis) or bleeding from your gums (gingival bleeding).
• Pulmonary embolism (a blockage in the lungs).
• Blood in the urine

Other General Warnings

• You have recently undergone surgery, experienced bleeding, or sustained injuries.
• You have serious heart, brain, liver, or kidney problems.
• You are elderly (especially over 75 years of age).
• You are taking blood thinners or ACE inhibitors.
• You notice bleeding or bruising, even at needle or injection sites.

• Store Dukinase powder for injection below 25°C, protect it from direct sunlight.
• Do not store above 25°C or freeze.
• Keep it out of the reach of children and pets.
• Discard the unused medicine.

Overdose

Missed a Dose

How Does It Work?

Interactions with other medicines

• Mixing Dukinase powder for injection with 5% glucose in plastic (PVC) containers may reduce its effectiveness.
• Using blood thinners like warfarin or heparin at the same time may increase the risk of bleeding.
• Medicines that affect how platelets work such as aspirin, clopidogrel, ibuprofen, dipyridamole, or dextrans. It can also raise the risk of bleeding.
• ACE inhibitors (commonly used for high blood pressure or heart conditions) may increase the chance of a serious allergic reaction called angioedema (swelling of the face, lips, or throat).
• Contrast dyes used in imaging procedures may slow down the rate at which Dukinase powder for injection dissolve clots.