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Clomach 50mg Tablet

10 Tablet(s) in Strip
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Clomach 50 MG Description

Clomach 50 mg tablet belongs to the class of atypical antipsychotics. It is primarily used to treat schizophrenia. Schizophrenia is a condition characterised by symptoms like delirium, hallucinations

, and abnormal thinking processes. The active ingredient in Clomach 50 mg tablets is Clozapine. Directions for use of Clomach 50 mg tablets should be strictly followed. The medicine should be taken at a fixed time every day to maintain stable levels of chemical substances (neurotransmitters) in the brain. Sudden stoppage of this medicine is to be avoided. Clomach 50 mg tablet withdrawal symptoms include nausea, vomiting, sleeplessness, and fatigue. Some of the most common side effects of Clomach 50 mg tablets are dry mouth, constipation, nausea, vomiting, drowsiness, and low blood pressure. Most of these side effects are mild and do not disrupt everyday life. Potential users should inform their doctor if they have been diagnosed with prolactinoma, breast cancer, or diabetes mellitus. Pregnant women should notify their doctor of their pregnancy status or intention to conceive as Clomach 50 mg tablets are not indicated in such cases. Clomach 50 mg tablets should be prescribed with precaution in older adults and those with kidney or liver disease. This medicine can cause weight gain and an increase in blood lipid levels. Exercising regularly and maintaining a healthy lifestyle can help manage these issues.


Product Summary

Offer Price₹45.04
You Save₹6.14 (12% on MRP)
ContainsClozapine(50.0 Mg)
Side effectsSweating, Low blood pressure levels, Visual impairment
Check more medicines with composition as Clozapine(50.0 Mg)

Uses of Clomach 50 MG

  • Clomach 50 mg tablets are used to treat schizophrenia.

Contraindications of Clomach 50 MG

  • Do not use Clomach 50 mg tablets or use caution in the following cases:
  • If you have been diagnosed with prolactinoma (tumour of the endocrine gland); Clomach 50 mg tablets can worsen the condition.
  • If you have been diagnosed with pheochromocytoma (tumour of the adrenal gland); Clomach 50 mg tablets should not be prescribed.
  • If you have had an allergic reaction to this medicine in the past.
  • If you are pregnant or planning to conceive.
  • If you are under 15.
  • If you want to breastfeed; this medicine decreases the secretion of breastmilk.
  • If you have pre-existing kidney diseases; Clomach 50 mg tablets should be prescribed with caution as the medicine excretes through the kidney.
  • If you have liver disease; dose modification is required.
  • If you have been diagnosed with heart disease; Clomach 50 mg tablets should be prescribed with caution as this medicine can increase the chances of stroke.
  • If you have a history of convulsions; dose modification should be done as Clomach 50 mg tablets decrease the seizure threshold.

Side effects of Clomach 50 MG

  • Low blood pressure levels
  • Involuntary muscle contractions
  • Restlessness
  • Constipation
  • Dry mouth
  • Weight gain

Precautions and Warnings of Clomach 50 MG



Can I take Clomach 50 mg tablets during pregnancy?
Clomach 50 mg tablets should not be taken during pregnancy. This medicine causes abnormal movements of limbs and withdrawal symptoms like agitation, feeding difficulties, decrease in respiratory rate, tremor, and sedation in babies.

Breast Feeding

Can I take Clomach 50 mg tablets while breastfeeding?
It is not advisable to take Clomach 50 mg tablets while breastfeeding as it can pass through breast milk and cause adverse effects like sedation, lethargy, poor feeding, and low blood pressure levels in the baby. Clomach 50 mg tablets can also decrease the production of breast milk.


Can I drive if I have taken a Clomach 50 mg tablet?
You should not drive after taking a Clomach 50 mg tablet because this medicine causes drowsiness and lethargy. You should also avoid operating any machinery as it causes impairment in judgement.


Can I consume alcohol with Clomach 50 mg tablets?
You should not consume alcohol with Clomach 50 mg tablets as the combination increases the severity of side effects like drowsiness and palpitations.

Other General Warnings

Talk to your doctor if
  • You have been diagnosed with diabetes. Blood sugar levels should be monitored at regular intervals.
  • You have liver disease and are prescribed Clomach 50 mg tablets. Get your liver function tests done at regular intervals.
  • You have low blood cell counts. Get your blood examination done at regular intervals as Clomach 50 mg tablets can decrease blood cell counts.
  • You are an older adult over 65. This medicine increases the chances of stroke in this age group.
  • You take other medicines for your health. Inform your doctor so they can check for any potential issues.
  • You experience breathing difficulty, fever, chest pain, or fast breathing. Immediately consult a doctor as these symptoms may signify myocarditis (swelling of heart muscle) or cardiomyopathy (thickeni...
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  • You have a history of heart disease. Clomach 50 mg tablets may increase the chances of heart failure.
  • You had convulsions in the past.
  • You are a smoker. Do not smoke while taking this medicine, as tobacco decreases the efficacy of Clomach 50 mg tablets.

Mode of Action of Clomach 50 MG

How Does It Work?

Clomach 50 mg tablet contains Clozapine as its active ingredient. Clozapine belongs to the group of atypical antipsychotics. This medicine binds to the dopamine receptors in the brain nerve endings. A...
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Directions for Use of Clomach 50 MG

  • Take this medicine exactly as prescribed by your doctor.
  • Do not exceed the recommended dosage.
  • If you have any side effects, seek medical help immediately.
  • Make sure that the treatment is complete.
  • Do not discontinue using this medication without consulting your physician first.
  • Keep the medicines in the container with the lid tightly closed.

Interactions of Clomach 50 MG

Interactions with other medicines

  • Clomach 50 mg tablets are known to interact with the following medication:
  • Antidepressants (bupropion, fluoxetine) cause drowsiness and impairment in judgement.
  • Anticoagulants (warfarin) increase the chances of bleeding.
  • Barbiturates (phenobarbital, secobarbital) cause sedation.
  • Medicines used in the treatment of mania like lithium increase the chances of coarse tremors.
  • Bronchodilators (ipratropium, tiotropium) increase the chances of tremors.
  • Antihistamines (cetirizine) cause drowsiness.
  • Cough medicine (dextromethorphan) increases the chances of drowsiness and dryness of the mouth.
  • Antiarrhythmics (propafenone, flecainide) increase the chances of palpitations and abnormalities in the heart rhythm.
  • Clomach 50 mg tablets decrease the efficacy of antifungals (ketoconazole).
  • Antacids (cimetidine, omeprazole) decrease the absorption of the Clomach 50 mg tablets.
  • Anti epileptics like phenytoin decrease the metabolism of phenytoin, leading to an increase in the concentration of phenytoin in the blood.

Interactions with food items

  • Avoid drinking caffeinated beverages while taking Clomach 50 mg tablets.

Storage and disposal of Clomach 50 MG

Store Clomach 50 mg tablets at room temperature below 30℃. Store it in an airtight container, away from the reach of children and pets. Keep the Clomach 50 mg tablets away from direct sunlight, heat, ...
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Dosage of Clomach 50 MG


Taking more than the recommended dose of Clomach 50 mg tablets can cause symptoms like decreased heart rate, low blood pressure, sedation, convulsions, and coma. You should immediately consult a docto...
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Missed a Dose

If you have missed a Clomach 50 mg tablet, try taking it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with your regu...
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Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: What should I do if I notice a change in taste after taking Clomach 50 mg tablets? Is this normal?

A: Clomach 50 mg tablets can cause changes in perception of taste. It is a known side effect of this medicine. You can rinse your mouth with a solution of salt and soda bicarbonate before having your meals to improve your taste perception before meals.

Q: For how long should I take Clomach 50 mg tablets?

A: Clomach 50 mg tablets should be taken at a dose and for a duration as prescribed by your doctor. You may start noticing improvement in your symptoms after a week of taking the medicines. However, you should not discontinue the medication without consulting a doctor. The sudden stoppage may cause withdrawal symptoms like nausea, sleepiness, numbness, agitation, and headache. The dose of the medicine is gradually reduced, and the response is continuously monitored before stopping the medication.

Q: Why are regular blood tests recommended while taking Clomach 50 mg tablets?

A: Clomach 50 mg tablets can cause a serious side effect called agranulocytosis, a condition in which white cells in the blood decrease drastically. This makes the user prone to infections. Though the side effect is rare, blood tests are recommended to prevent this serious side effect.
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Last Updated on: 04 Apr 2022 | 09:52 AM (IST)

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