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Molecule Description

Flunarizine is a selective calcium channel blocker and used to treat migraine headaches.

Uses of Flunarizine

  • Prophylaxis of migraine
  • Occlusive peripheral vascular disease
  • Vertigo of central and peripheral origin
  • Adjuvant in the therapy of epilepsy
  • Treatment of dizziness

Contraindications of Flunarizine

When should one not use Flunarizine

  • Depression
  • In the acute phase of stroke
  • In patients with extrapyramidal symptoms or Parkinson’s disease
  • Low blood pressure
  • Heart failure
  • Irregular heartbeats

Side effects of Flunarizine

Common side effects of this drug are:

  • Drowsiness
  • Weight gain
  • Nausea
  • Heartburn
  • Dry mouth
  • Depression
  • Decrease in sleep
  • Increase in appetite

Precautions and Warnings of Flunarizine


Can I take Flunarizine during pregnancy?
There are no adequate studies or data available about the usage of this medicine during pregnancy; hence, this medicine is not recommended during pregnancy.

Breast Feeding

Can I take Flunarizine while breastfeeding?
This medicine is not recommended during breastfeeding as there are no adequate studies or data available about the usage of this medicine during breastfeeding.


Can I consume alcohol with Flunarizine?
Alcohol and Flunarizine can increase drowsiness. Hence, alcohol should be avoided.

Other General Warnings

Talk to your doctor if
  • If you have depression
  • If you are taking any medicines which causes drowsiness
  • If you have any heart-related problems
  • If you have low blood pressure

Mode of Action of Flunarizine

How Does It Work?

  • Flunarizine blocks certain types of voltage-gated calcium channels, thereby prevents the entry of calcium; this inhibits the contractions of vascular smooth muscle cells. Collectively, it increases blood flow to the brain and heart
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  • It also has Histamine H1 blocking activity

Interactions of Flunarizine

Interactions with other medicines

This medicine has interactions with anticonvulsants and tranquilizers.

Interactions with food items

  • Using alcohol with this medicine may cause interactions
  • Consumption of alcohol while taking this medicine should be avoided

Dosage of Flunarizine


Overdose symptoms may include confusion, unusual drowsiness and rapid pulse. If overdose is suspected, seek emergency medical care immediately.

Missed a Dose

Take medicine as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and go back to the regular dosage schedule. Do not take extra medicine to compensate for the missed dose.
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Content Details


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What should I discuss with my healthcare expert before taking this medicine?

A: You should not use this medication if you are allergic to it. You must give a detailed account of your medical and surgical history. Also, discuss with your doctor all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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