Nicip Plus Tablet
10 Tablet(s) in Strip
Product Summary
Nicip Plus Tablet is a pain-relieving and fever-reducing medicine from Cipla, containing nimesulide 100 mg and paracetamol 325 mg for treating headache, toothache, ear pain, joint pain, menstrual pain and fever. Nimesulide reduces formation of prostaglandins involved in pain. Paracetamol acts on the brain area that regulates body temperature.
Medically Reviewed by Dr. Avinav Gupta
Last updated on: 14 October 2026 | 3:53 PM (IST)
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Dose Form
TABLET
Expiry
General Information
| Therapy | Analgesic/antipyretic |
| Composition | Nimesulide(100.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg) Nimesulide 100.0 Mg+Paracetamol / Acetaminophen 325.0 Mg |
Nimesulide 100.0 Mg+Paracetamol / Acetaminophen 325.0 Mg
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*Offer applicable on orders above ₹1000About Nicip Plus
Nicip Plus tablet is a pain- and fever-reducing medicine. It is used to treat painful conditions such as headache, fever, period pain, and dental, joint, and ear pain. The tablet contains a combination of nimesulide and paracetamol as active substances. It works by preventing the action of these pain and fever-causing chemicals.
Take this medicine at the exact dose and duration your doctor recommends. Swallow it as a whole with a glass of water. Do not take more than the prescribed dose. This medicine for more than 10 days is not recommended unless prescribed by your doctor. Taking more than the daily dose of this medicine may cause severe liver damage or allergic reactions like swelling of the face, mouth and throat, difficulty in breathing, itching or rashes.
Other medicines containing nimesulide and paracetamol are Nimucet Gold tablet, Nobel Plus tablet, Nodard Plus tablet, Sumo tablet, and Somee tablet.
Do not take this medicine if you are allergic to its components. Before taking Nicip Plus tablet, inform your doctor if you are pregnant, planning on becoming pregnant or breastfeeding and about your complete medical history. Also, inform the doctor about all other medicines and supplements you take. This medicine is not recommended for children below 12 years of age.
Uses
- For short-term relief of acute pain and inflammation when prescribed by a doctor.
- For relief of fever when prescribed by a doctor.
Contraindications
- If you are allergic to paracetamol, nimesulide, other pain-relieving medicines, or other ingredients of Nicip Plus tablet.
- If you have a history of liver damage induced by nimesulide or other medicines.
- If you have or had a history of stomach bleeding, ulcer, or inflammation of the stomach lining.
- If you have a blood-clotting or bleeding disorder.
- If you have impaired liver or kidney function or severe heart failure problems.
- If you consume alcohol frequently or have an alcohol use disorder.
- If you are pregnant or are breastfeeding.
- In children below 12 years of age.
Side effects
- Rashes
- Nausea
- Vomiting
- Loose stools/diarrhoea
- Redness of skin
Precautions and Warnings
Alcohol
Avoid alcohol while taking Nicip Plus. Alcohol can increase the risk of liver injury and stomach or intestinal bleeding. Tell your doctor if you drink regularly or have a history of alcohol misuse.
Pregnancy
Do not use Nicip Plus tablet during pregnancy, especially in the third trimester. Also, do not take this medicine if you are trying to conceive or taking any fertility treatment. This medicine can affect your fertility.
Breastfeeding
Do not take Nicip Plus while breastfeeding unless your doctor has specifically assessed its use. Consult your doctor before taking any medicine while nursing.
Driving
You may feel drowsy and sleepy after taking Nicip Plus tablet. Do not drive or operate machinery if you experience these symptoms or feel less alert.
Other General Warnings
- You experience loss of appetite, nausea, stomach pain, and weakness. These could be signs of serious liver damage.
- If you develop black, tarry stools or vomit blood, Stop the medicine and seek urgent medical help.
- If you are elderly, your risk of side effects increases.
- You are suffering from liver, kidney, or heart disease.
- You have a history of stomach or intestine ulcers.
- You are scheduled for any upcoming surgery.
- You are taking any other medicine containing paracetamol, or any other anti-inflammatory painkiller including aspirin.
- You have asthma, or aspirin or another painkiller has ever caused wheezing, nasal symptoms or hives.
- You drink alcohol regularly, as this raises both the liver risk and the risk of stomach bleeding.
- You take a blood thinner, a steroid tablet, an SSRI antidepressant, a water tablet or a blood pressure medicine.
- You are still in pain after a few days, as the cause needs reviewing rather than the course being extended.
- This is a short-course medicine. Nimesulide is restricted in several countries because of the risk
Directions for use
- Consume Nicip Plus whole with enough water.
- Take it after food to avoid stomach discomfort.
- Take this medicine for a short duration to avoid side effects.
- Take it only as long as it controls your symptoms. If you still need a painkiller after a few days, go back to your doctor rather than continuing on your own.
- Do not take any other medicine containing paracetamol at the same time, and do not take another anti-inflammatory painkiller such as ibuprofen, diclofenac or aceclofenac alongside it.
- Avoid alcohol while taking it. Alcohol increases both the liver risk and the risk of stomach bleeding.
- Drink enough fluid while taking it, particularly in hot weather or if you have been vomiting or have diarrhoea, as dehydration increases the strain on the kidneys.
- Do not give this medicine to a child under 12 years of age.
- Tell your doctor or dentist that you take it if you are due to have surgery.
Storage and disposal
- Store Nicip Plus tablets in a cool, dry place, protected from moisture.
- Keep it out of reach of children and pets.
- Keep the tablets in the original strip until you take them. Do not use them after the expiry date.
- Do not keep a part-used strip to treat a future episode of pain without speaking to your doctor.
Quick tips
- Use Nicip Plus Tablet cautiously if you have liver problems, as it increases the risk of severe side effects.
- Nicip Plus is recommended for short-term use only. Do not take more than the daily dose of Nicip Plus tablet, as it may affect the liver or cause allergic reactions.
- You should inform your doctor if you have experienced asthma, rhinitis, or hives after taking aspirin or other NSAIDs in the past.
- Talk to your doctor if you have a history of alcohol misuse or drink alcohol regularly.
- Know the liver warning signs: loss of appetite, persistent nausea, pain under the right ribs, dark urine, or yellowing of the skin or eyes. Stop the tablet and see a doctor.
- Know the bleeding warning signs: vomiting blood or coffee-ground material, or black tarry stools. Seek urgent help.
- Never take it with another paracetamol product or another anti-inflammatory painkiller. Check the ingredients on every pack.
- Avoid alcohol while taking it.
- Take it after food, and keep well hydrated.
- Not for children under 12 years of age.
- If you need a painkiller regularly, see your doctor about the underlying cause rather than continuing this one.
Dosage
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How Nicip Plus works
Interactions
Drug interactions of Nicip Plus with other medicine salt
Food interactions
Frequently asked questions
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References
- Nimesulide Tablet [Internet]. Ema.europa.eu. 2022 [cited 11 August 2022]
- Alcohol and NSAIDs Increase Risk for Upper GI Bleeding [Internet]. American Academy of Family Physicians. 2022 [cited 11 August 2022]
- Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2022 [cited 11 August 2022]
- Nimesulide & Paracetamol Tablets – Salvavidas Pharmaceutical [Internet]. Salvavidaspharma.com. 2022 [cited 11 August 2022]
- PubChem. Nimesulide [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2024 [cited 23 December 2024].
- Paracetamol. ScienceDirect. 2024 [cited 23 December 2024].
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