Cyra D Capsule
10 Capsule(s) in StripProduct Summary
Cyra D Capsule combines rabeprazole 20 mg and domperidone 30 mg to treat gastroesophageal reflux disease, or GERD, and is manufactured by Systopic Laboratories. Rabeprazole, a proton pump inhibitor, reduces stomach acid, while domperidone improves gut movement to reduce backflow.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 9:05 AM (IST)
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SYSTOPIC LABORATORIES
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General Information
| Therapy | Antacid and anti-emetic |
| Composition | Rabeprazole(20.0 Mg)+Domperidone(30.0 Mg) Rabeprazole 20.0 Mg+Domperidone 30.0 Mg |
Rabeprazole 20.0 Mg+Domperidone 30.0 Mg

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*Offer applicable on orders above ₹1000About Cyra
Cyra D capsule is used to treat acid-related conditions such as heartburn, acidity, and gastroesophageal reflux disease (GERD). It is also helpful in managing gastric and duodenal ulcers. Cyra D is an anti-reflux medication that combines rabeprazole and domperidone as active ingredients. It alleviates acid-related symptoms like heartburn, stomach pain, and irritation. Cyra D also neutralizes acid and improves gas flow, thereby reducing stomach discomfort.
Other capsules containing rabeprazole and domperidone are Veloz D capsule, Razo D capsule, Rabekind DSR capsule, Rabesec DSR capsule, and Rabium DSR capsule.
For the best results, Cyra D capsules should be taken at least 30 minutes before meals. Before your doctor prescribes the capsule, tell him about your health conditions.
Before using this capsule, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history. Avoid consuming spicy and oily food. You should eat at least 3 hours before going to bed. Do not eat at bedtime. Engage yourself in exercise and activities. Avoid smoking and drinking alcohol, as it may worsen the condition.
Uses
- Cyra-D capsule is used to treat gastrointestinal reflux disease (GERD) with or without ulcers. This condition leads to acid regurgitating from the stomach into the food pipe, causing heartburn, chest discomfort and acidity.
- It is also used for the treatment of Zollinger-Ellison syndrome, a condition where one or more tumours make excessive amounts of acid.
Contraindications
- If you are allergic to rabeprazole or domperidone, or any of the ingredients of Cyra-D capsule.
- If you are suffering from any liver or kidney problems.
- If you have serious heart problems like heart failure, heart rhythm problems, electrolyte imbalance.
- If you are taking any medicine that might affect the heart muscle's contraction (QT prolongation).
- If you are suffering from bleeding in your digestive system.
- If you have any pituitary gland tumour (Prolactin pituitary tumours).
- If you are pregnant, think you may be or are breastfeeding.
Side effects
- Nausea
- Vomiting
- Sore throat
- Cough
- Stomach pain
- Flatulence
Precautions and Warnings
Alcohol
WITH CAUTIONConsuming alcohol while on treatment with Cyra-D capsule does not affect the way it works. However, you should avoid drinking alcohol in excess as it is known to increase acidity and can make your acidity worse.
Pregnancy
CONTRAINDICATEDCyra-D capsules should not be used in pregnancy as components of this capsule may harm your unborn baby. It is essential to always consult a doctor before starting any medicine during pregnancy.
Breastfeeding
WITH CAUTIONComponents of Cyra-D capsule pass into the breastmilk in small amounts and might affect your baby. Consult your doctor if you are breastfeeding, after assessing the benefits over risks your doctor might change the medicine, ask you to stop breastfeeding or closely monitor the baby for any side effects.
Driving
WITH CAUTIONIf you experience drowsiness and visual disturbances (altered vision) after taking Cyra-D capsules, it is advised not to drive or use machines.
Other General Warnings
- You have problems with your liver and kidney.
- You have heart problems and experience symptoms like palpitations, difficulty in breathing, and unconsciousness.
- You develop watery diarrhoea and fever after taking Cyra-D capsules.
- You notice black or dark stools.
- You have a stomach tumour.
- You have a history of fractures or have osteoporosis, or are taking steroids.
- You are taking medicines to treat HIV infection, like ritonavir.
- After taking this capsule, you develop skin lesions, especially in the sun-exposed area.
- You have low levels of vitamin B12. This capsule is known to reduce vitamin B12 absorption after long-term use. Supplements may be needed.
- You have been taking Cyra-D capsules for more than three months. Your blood magnesium levels may drop, and your doctor may perform regular tests for the same.
Doctor’s suggestion

Directions for use
Storage and disposal
- Store Cyra-D capsules in a cool and dry place, protected from direct sunlight, moisture and heat.
- Keep it away from children and pets.
- Do not use expired medicines. Discard any unused medicine properly, do not flush in the toilet or throw it into the drain.
Quick tips
- You can make certain lifestyle modifications like preventing excess intake of foods that cause acidity, like carbonated drinks and oily/fried food, regular exercise and maintaining a healthy weight.
- Reduce alcohol consumption and quit smoking to improve the treatment of acid reflux. It's worth noting that using Cyra-D Capsule can cause dry mouth due to Domperidone. If you experience dry mouth, drinking plenty of water throughout the day and keeping a glass of water by your bedside at night is important.
- Taking Cyra-D capsules for more than 1 year may increase the risk of bone fractures.
- Cyra-D capsules are not recommended for use in children under 12 years of age.
Dosage
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Interactions
Drug interactions of Cyra with other medicine salt
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References
- RABICIP D Capsules [Internet]. CiplaMed. 2024 [cited 30 September 2024]
- Domperidone Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 14 April 2022]
- Domperidone Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 14 April 2022]
- Rabeprazole 20mg Gastro-resistant Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 14 April 2022]
- Rabeprazole 20mg Gastro-resistant Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 14 April 2022]
- CDSCO - Rabeprazole + Domperidone [Internet]. Cdscoonline.gov.in. 2022 [cited 11 August 2022]
- Zamani, N. F., Sjahid, A. S., Tuan Kamauzaman, T. H., Lee, Y. Y., & Islam, M. A. (2022). Efficacy and Safety of Domperidone in Combination with Proton Pump Inhibitors in Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Journal of Clinical Medicine, 11(18), 5268.
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