Rabeprazole+Domperidone is used for the treatment of gastrointestinal reflux di
sease (GERD). It works by reducing the amount of acid produced in the stomach and improves motility in the gut. Thus, it reduces the backflow of stomach content to the food pipe. Rabeprazole+Domperidone is available in the form of tablet, capsule. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from before starting Rabeprazole+Domperidone.
Uses of Rabeprazole+Domperidone
Rabeprazole+Domperidone is used to treat gastrointestinal reflux disease (GERD).
Contraindications of Rabeprazole+Domperidone
When should one not use Rabeprazole+Domperidone
- If you are allergic to Rabeprazole+Domperidone.
- If you have problems with your heart, liver or kidney.
- If you are suffering from bleeding in the digestive system.
- If you are pregnant, planning to get pregnant or are breastfeeding.
- If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
- If you are taking any medications that may affect the contraction of the heart muscle (QT prolongation).
Side effects of Rabeprazole+Domperidone
Common side effects of this drug are:
- Stomach pain
- Dry mouth
- Skin rash
Precautions and Warnings of Rabeprazole+Domperidone
Can I take Rabeprazole+Domperidone during pregnancy?
It is not advised to take Rabeprazole+Domperidone during pregnancy until it is considered essential by the doctor and potential risks justify the benefits.
Can I take Rabeprazole+Domperidone while breastfeeding?
Rabeprazole+Domperidone passes in the breastmilk in a small amount. Your doctor may prescribe you this medicine while you are breastfeeding, only if it is necessary. Inform your doctor if you are a nursing mother.
Can I drive if I have consumed Rabeprazole+Domperidone?
Rabeprazole+Domperidone may cause sleepiness, thus you need to be cautious while driving.
Can I consume alcohol with Rabeprazole+Domperidone?
Avoid consuming alcohol with Rabeprazole+Domperidone, as it may worsen the side effects.
Other General Warnings
Talk to your doctor if
- You are suffering from any heart (associated symptoms like palpitations, difficulty in breathing, unconsciousness), liver or kidney disease.
- You have a stomach tumour.
- You have a history of fractures or have osteoporosis or are taking steroids.
- You develop watery/black stools or fever after taking this medicine.
- You have low levels of vitamin B12.
- Your blood magnesium levels may drop if you are taking Rabeprazole+Domperidone for more than three months. Your doctor may perform regular tests.
- You develop skin lesions, especially in the sun-exposed area, after taking this medicine.
- You are taking medicines to treat HIV.
- Taking Rabeprazole+Domperidone for more than one year may increase the chances of developing bone fractures.
Mode of Action of Rabeprazole+Domperidone
How Does It Work?
- A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Rabeprazole binds to this proton pump in stomach cells, thus blocking acid secretion.
- Domperidone increases the motility of the stomach and intestines so that acid does not reflux back into the food pipe.
Interactions of Rabeprazole+Domperidone
Interactions with other medicines
- Some medicines can affect the way Rabeprazole+Domperidone works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
- Especially if you are taking medicine to treat your heart problems, mental health problems, fungal or bacterial infections or are taking blood thinners.
- Rilpivirine should not be used along with this medicine.
- Medicines like disopyramide, amiodarone, medicines to treat psychiatric problems like haloperidol, Citalopram, antibiotics like erythromycin, levofloxacin, azithromycin, antifungals like Pentamidine, ketoconazole and other medicines like cisapride, dolasetron, mequitazine, etc., should not be used along with this medicine....
Dosage of Rabeprazole+Domperidone
Symptoms of overdose may include drowsiness, confusion, mood disorders, altered consciousness. Seek urgent medical help if you suspect an overdose.
Missed a Dose
If you have missed any dose of Rabeprazole+Domperidone, then take it as soon as you remember. If it is already time for the next dose, then skip the missed dose and follow the regular dosing schedule. Do not take a double dose to compensate for the missed one....
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery)
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Is Rabeprazole+Domperidone a steroid?
A: No, Rabeprazole+Domperidone is not a steroid. It is an anti-reflux medicine.
Q: In which all dosage forms is Rabeprazole+Domperidone available?
A: Rabeprazole+Domperidone is available in the form of tablet, capsule.
- CDSCO [Internet]. Cdscoonline.gov.in. 2021 [cited 7 October 2021]
- RABICIP D Capsules [Internet]. CiplaMed. 2021 [cited 7 October 2021]
- Domperidone 10mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 7 October 2021]
- Domperidone 10mg Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 7 October 2021]
- Rabeprazole 20mg Gastro-resistant Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 7 October 2021]
- Rabeprazole 20mg Gastro-resistant Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 7 October 2021]
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