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Zyven Od Plus 50mg Tablets

10 Tablet(s) in Strip
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Zyven Od Plus 50mg Tablets Description

Zyven Od Plus Tablet is a prescription medicine used in the treatment of depression. Depression is a mental disorder characterised by persistent feelings of sadness and hopelessness that disrupts nor

mal life. Zyven Od Plus Tablet has desvenlafaxine and clonazepam as the main ingredients. Desvenlafaxine is a type of antidepressant, and clonazepam is a type of benzodiazepine. Both act in combination by balancing certain chemicals in the brain that further helps in instilling the feeling of well being. Zyven Od Tablet should be taken only if recommended by a doctor. It is usually prescribed as a long term medicine and has to be consumed daily. Zyven Od Plus Tablets can exhibit certain side effects like nausea, tiredness, constipation, sweating, dry mouth and dizziness. The dose and duration of the Zyven Od Plus tablet should be maintained as per doctor’s advice.


Product Summary

Offer Price₹185.45
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ContainsDesvenlafaxine(50.0 Mg) + Clonazepam(0.5 Mg)
UsesDepression and major depressive disorder
Side effectsnausea, tiredness, constipation, sweating, dry mouth and dizziness.
Check more medicines with composition as Desvenlafaxine(50.0 Mg) + Clonazepam(0.5 Mg)

Uses of Zyven Od Plus 50mg Tablets

  • Zyven Od Plus Tablet is used in,
  • Treatment of depression
  • Treatment of major depressive disorder (a type of depression with a consistent feeling of sadness and low mood)

Contraindications of Zyven Od Plus 50mg Tablets

  • If you are allergic or hypersensitive to desvenlafaxine, clonazepam, or the inactive ingredient of Zyven Od Plus Tablet.
  • If you are currently using MAO Inhibitors like selegiline. Zyven Od Plus can be consumed only after 14 days of stopping MAO Inhibitors.

Side effects of Zyven Od Plus 50mg Tablets

  • Nausea
  • Tiredness
  • Constipation
  • Sweating
  • Dry mouth
  • Dizziness
  • Insomnia
  • Loss of appetite
  • Reduced sex drive

Precautions and Warnings of Zyven Od Plus 50mg Tablets



Can I take Zyven Od Tablet during pregnancy?
Zyven Od Tablet is considered unsafe and is not recommended during pregnancy. Inform the doctor if you are pregnant or are planning a baby. The doctor will consider your particular situation and will advise the best for you.

Breast Feeding

Can I take Zyven Od Tablet while breastfeeding?
Breastfeeding while taking Zyven Od Tablet is generally not recommended. Inform your doctor if you are breastfeeding for the best advice.


Can I drive if I have taken Zyven Od Tablet?
Zyven Od Plus Tablet is known to cause drowsiness, dizziness, and decreased concentration. Hence, it is advised to avoid driving after taking the medicine.


Can I consume alcohol with the Zyven Od Plus Tablet?
Consuming alcohol may increase the feeling of drowsiness and confusion, and can lead to serious side effects. Therefore, alcohol consumption while taking Zyven Od Tablets is not recommended.

Other General Warnings

Talk to your doctor if
  • You have a history of liver or kidney disorder.
  • You do not notice any changes after more than a month of taking the Zyven Od Tablets. It usually takes 2-4 weeks to see any effect of the Zyven Od Tablets. Continue taking medicine as advised.
  • You continue feeling restless. It can happen within weeks of starting the Zyven Od Tablets.
  • You notice changes in thoughts or increased suicidal thoughts and hallucinations.
  • Your job requires you to operate heavy machinery or drive a vehicle while undergoing treatment of Zyven Od Plus Tablet.
  • You have increased blood pressure.
  • You feel pressure in your eyes or any sort of visual changes.
  • You want to alter the dose of Zyven Od Tablet or want to discontinue the medicine.

Mode of Action of Zyven Od Plus 50mg Tablets

How Does It Work?

The active components of Zyven Od Plus Tablet are desvenlafaxine and clonazepam. Desvenlafaxine is a type of Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs). It works by increasing ...
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Directions for Use of Zyven Od Plus 50mg Tablets

  • Zyven Od Tablet can be taken with or without food.
  • For optimal pharmacological effects, take Zyven Od Tablet schedule at the same time every day.
  • Swallow Zyven Od Tablet whole with some water. Do not chew, crush or break it.
  • Do not alter the dose of Zyven Od Tablet without consulting your doctor.
  • Do not discontinue the use of Zyven Od Tablet abruptly, as this may worsen your condition.

Interactions of Zyven Od Plus 50mg Tablets

Interactions with other medicines

  • To avoid side effects associated with medicine interactions, it is important to inform the doctor about all medicines and health supplements you are currently taking.
  • Zyven Od Plus tablet is known to interact with:;
  • Aspirin, clopidogrel (blood thinners)- it can increase the risk of bruising and bleeding
  • Acetaminophen (painkiller), azithromycin (antibiotic)- it can decrease the metabolism of acetaminophen and azithromycin if used in combination
  • Almotriptan (migraine medicine) - it can increase the risk of severity of side effects
  • Fluoxetine (antidepressant) - it can increase the risk of serotonin syndrome characterised by insomnia, muscle rigidity, agitation, high blood pressure, confusion and increased heart rate
  • Nitrofurantoin (antibiotic)- it can increase the concentration of Zyven Tablet in the body

Interactions with food items

  • Zyven Od Plus tablet is not known to interact with any particular food item. A regular diet can be followed unless advised otherwise by the doctor.

Storage and disposal of Zyven Od Plus 50mg Tablets

Store Zyven Od Plus Tablets at room temperature and away from any source of direct heat. Do not keep the tablets in direct sunlight. Zyven Od Tablets do not need refrigeration. Keep the medicine away ...
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Dosage of Zyven Od Plus 50mg Tablets


An overdose of Zyven Od Tablets can exhibit symptoms like headache, vomiting, agitation, dizziness. If you have overdosed on Zyven Od Tablets, reach out to your doctor or the nearest hospital immedia...
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Missed a Dose

If you miss a dose of Zyven Od Plus Tablet, take the tablet as soon as you remember. If the gap is too long or it is almost the time of the next dose, skip the dose you have missed and continue with t...
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Content Details


Dr. Suneet Monga

BDS, MDS (Paediatric & Preventive Dentistry) MMCDSR


Dr. Vijay Y

MBBS, MD in Clinical Pharmacology

Frequently Asked Questions (FAQs)


Q: I have had constipation for a few days after taking Zyven Od Plus Tablet. What should I do?

A: Report to your doctor if any of the side effects do not go away on their own or if they worsen in time. Try to have a diet rich in fibre and include fresh fruits and vegetables in the routine.

Q: Is Zyven Od Plus Tablet habit-forming?

A: No. Zyven Tablets are not known to cause any dependence. However, it is important to stick to the prescribed dose and duration for optimum use.

Q: Is there any specific diet I need to follow while having Zyven Od Tablets?

A: No specific dietary modifications are required while having Zyven Od Tablets. Maintain a healthy lifestyle with the help of nutrient-dense food and exercising every day.
Product Details
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Last Updated on: 02 Apr 2022 | 11:04 AM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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