Valance 500mg Bottle Of 100ml Colourless Solution
By ABBOTT HEALTHCARE PVT LTD
100ml Oral Solution in Bottle
₹292.53
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₹370.29
21% OFF
₹2.93/ml
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Description
Valance oral solution is a medicine used to manage manic episodes in people with bipolar disorder, especially when other treatment options are not suitable or well tolerated. During a manic phase, a person may feel unusually energetic, irritable, restless, overly confident, or may sleep very little. This medicine helps calm these symptoms and brings mood and behaviour back toward balance. In some patients who respond well, the doctor may advise continuing treatment to help prevent future mood episodes.
This medicine works by stabilising activity in the brain. It increases the effect of a natural calming chemical called GABA, which helps reduce overactive nerve signals. By doing this, Valance oral solution helps control mood swings, reduce agitation, and improve emotional stability. It is important to take it exactly as prescribed, at the same time each day, and preferably with or after food to reduce stomach discomfort.
Valance oral solution is not suitable for everyone. It should not be used during pregnancy because it can seriously harm the unborn baby, and special precautions are required for women who could become pregnant. It is also not recommended for people with certain liver problems, metabolic disorders, or specific genetic conditions. Regular medical follow-up and blood tests may be needed to ensure the medicine remains safe and effective.
Some people may experience side effects such as nausea, vomiting, tremors, diarrhoea, or stomach pain, especially when starting treatment. Drowsiness can occur, so activities like driving should be avoided until you know how the medicine affects you. Alcohol is best avoided, as it can increase side effects and strain the liver. Always inform your doctor about other medicines you are taking and never stop or change the dose on your own.
Product Summary
| Offer Price | ₹292.53 |
| You Save | ₹77.76 (21% on MRP) |
| Contains | Divalproex Sodium(500.0 Mg/5ml) |
| Uses | Acute mania |
| Side effects | Nausea, tremor (shaking of hands or body) |
| Therapy | ANTI-EPILEPTIC |
Uses
- Valance oral solution is used for the treatment of manic episodes associated with bipolar disorder when other effective or well-tolerated treatment options are not suitable. It helps control symptoms such as extreme mood elevation, irritability, increased activity, and reduced need for sleep....
- In patients who respond well to Valance oral solution during an acute manic episode, continuation of treatment may be considered to help maintain mood stability and reduce the risk of recurrence, as advised by the doctor....
Contraindications
- If you are allergic to divalproex sodium or any of the other ingredients.
- If you are pregnant.
- If you are a woman of childbearing potential under 55 years, unless two specialists agree that no other treatment works and pregnancy prevention measures are in place.
- If you have active liver disease or a personal/family history of serious liver problems.
- If you have a known urea cycle disorder.
- If you have porphyria.
- If you have a mitochondrial disorder caused by POLG gene mutations, or if you are a child under two suspected of having such a disorder.
- If you have uncorrected primary carnitine deficiency.
Side effects
- Nausea
- Tremor
- Vomiting
- Diarrhoea
- Abdominal pain (gastralgia)
Precautions and Warnings
Pregnancy
Q:
Can I take Valance oral solution during pregnancy?
A:
No, Valance oral solution should not be used during pregnancy. It is particularly unsafe for women of childbearing age under 55 unless two specialists agree that there is no other effective or tolerated treatment and strict pregnancy prevention measures are followed. Always consult your doctor before using this medicine.
Breast Feeding
Q:
Can I take Valance oral solution while breastfeeding?
A:
Valance oral solution passes into breast milk, and some effects on blood cells have been seen in breastfed infants. You and your doctor should carefully weigh the benefits of breastfeeding against the need for treatment. Your doctor may advise stopping either the medicine or breastfeeding to ensure safety.
Driving
Q:
Can I drive if I have consumed Valance oral solution?
A:
Valance oral solution may cause temporary drowsiness, especially if taken with other medications or benzodiazepines. Avoid driving or operating machines until you know how the medicine affects you.
Alcohol
Q:
Can I consume alcohol with Valance oral solution?
A:
You should limit your alcohol consumption while you are undergoing treatment with Valance oral solution.
Other General Warnings
Talk to your doctor if
- You experience unusual drowsiness, especially when taking other medicines or benzodiazepines.
- You notice any signs of liver problems such as fatigue, loss of appetite, nausea, vomiting, abdominal pain, or yellowing of the skin/eyes.
- You have a personal or family history of liver disease, mitochondrial disorders, urea cycle disorders, or carnitine deficiency.
- You experience symptoms of hyperammonaemia, including confusion, unsteady walking, or vomiting.
- You notice severe abdominal pain, persistent nausea, or vomiting, which could indicate pancreatitis.
- You are at risk of pregnancy or planning a pregnancy, as valproate can cause serious birth defects and developmental disorders.
- You have suicidal thoughts, unusual mood changes, or behavioural changes.
- You notice severe skin reactions, rashes, swelling of face or throat, or other signs of allergic reactions.
- You experience unusual bleeding, bruising, or signs of blood disorders.
- You are taking carbapenem antibiotics, as they may interact with valproate.
- You have kidney problems or systemic lupus erythematosus, as dose adjustments or monitoring may be needed.
- You experience significant weight gain or changes in appetite during treatment.
- You consume alcohol, as it is not recommended while taking valproate.
Directions for Use
- Take Valance oral solution exactly as prescribed by your doctor.
- Measure the dose accurately using a measuring cup or oral syringe.
- Take it with or after food to reduce stomach upset.
- Take the medicine at the same time each day for best results.
- Do not stop or change the dose without consulting your doctor.
Storage and disposal
- Store Valance oral solution in a cool, dry place, protected from direct sunlight, moisture, and heat.
- Keep it out of the reach of children and pets.
Quick Tips
- Take Valance oral solution exactly as prescribed and at the same time every day.
- Take it with or after food to reduce nausea or stomach upset.
- Measure the dose carefully using a proper measuring cup or oral syringe.
- Do not stop the medicine suddenly unless advised by your doctor.
- Avoid alcohol, as it can increase drowsiness and affect the liver.
- Avoid driving or operating machinery until you know how the medicine affects you.
- Inform your doctor about all other medicines you are taking.
- Watch for unusual symptoms such as excessive sleepiness, abdominal pain, yellowing of eyes or skin, or mood changes.
- Maintain a healthy diet and stay active to help manage weight gain.
- Keep regular follow-up visits and blood tests as advised by your doctor.
Dosage
Overdose
If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you miss any dose of Valance oral solution, take it as soon as you remember with food. However, if it is time for the next dose, then skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up....
Mode of Action
How Does It Work?
Divalproex sodium works by calming overactive nerve signals in the brain. It increases a natural chemical called GABA, which helps to balance brain activity, stabilize mood, prevent manic episodes, and control seizures....
Interactions
Interactions with other medicines
- Can increase effects of antipsychotics, antidepressants, MAO inhibitors, or benzodiazepines.
- Can raise risk of low white blood cells and heart problems with clozapine.
- Usually safe with haloperidol or lithium, but monitoring is advised.
- May lower olanzapine levels in the blood.
- Can increase levels of some seizure medicines such as phenobarbital, primidone, phenytoin, carbamazepine, and lamotrigine; dose adjustments or monitoring may be needed.
- May slightly raise levels of felbamate, rufinamide, propofol, zidovudine, or nimodipine; monitoring may be needed.
- Some medicines such as rifampicin, protease inhibitors, anti-malarials, cholestyramine, metamizole, and methotrexate may lower Valance oral solution levels; dose adjustments or monitoring may be needed....
- Hormonal contraceptives may slightly reduce levels; monitoring is advised.
- Using multiple anti-seizure medicines or cannabidiol may increase risk of liver problems.
- Certain drugs such as pivalate-conjugated medicines, topiramate, and acetazolamide may increase risk of side effects; monitoring is needed.
- Quetiapine may increase risk of low white blood cells.
Interactions with food items
- Can be taken with or after food to reduce stomach upset like nausea or vomiting.
- Alcohol should be avoided during treatment as it can increase drowsiness and affect liver health.
- No specific foods are strictly prohibited, but maintaining a balanced diet is recommended.
- Large amounts of high-fat meals may slow absorption slightly, but it usually does not affect overall effectiveness.
- Staying hydrated and maintaining healthy nutrition helps reduce risk of weight gain and liver strain.
Content Details
WRITTEN BY
Ravindra Ghongade
B. Pharm
REVIEWED BY
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: What is Valance oral solution used for?
A: Valance oral solution is used to treat manic episodes in bipolar disorder when other treatment options are not effective or suitable. It helps control symptoms like extreme mood elevation, irritability, overactivity, and reduced need for sleep.
Q: Can Valance oral solution cause drowsiness?
A: Yes, it may cause drowsiness, especially at the start of treatment or when taken with other medicines. Avoid driving until you know how it affects you.
References
- Central Drugs Standard Control Organization (CDSCO). Drugs: Approved Drugs / Vaccines / r-DNA / Blood Products [Internet]. Government of India; [cited 2026 Jan 21]
- Sanofi. Depakote® 250 mg tablets (valproate semisodium): Summary of Product Characteristics [Internet]. UK: Datapharm Ltd.; [cited 2026 Jan 21].
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Product Details
Brand
VALANCE
Address
Abbott Healthcare Pvt. Ltd Village Bhatauli Khurd, Po. Baddi - 173 205, Dist Solan Himachal Pradesh India
Country of Origin
India
Expiry Date
01/05/2026
Manufacturer Details
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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