By CAPTAB BIOTECH
0.04g Powder For Injection in Injection
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Tolin Inj contains the active substance Pantoprazole that belongs to a group of medicines called "Proton pump inhibitor," medications that reduce the amount of acid produced in the stomach.
Uses of Tolin Inj
- Treatment of heartburn, acid regurgitation (sensation of acid in your throat or mouth), pain while swallowing that is caused due to gastro-oesophageal reflux disease
- In the treatment of reflux oesophagitis (inflammation of oesophagus with regurgitation of acid in the stomach)
- In adults, it is used to prevent small intestine and stomach ulcers that are caused by long term use of painkillers called NSAIDs, e.g., Ibuprofen
- To treat one or more tumors formed in pancreas or upper part of small intestine (Zollinger-Ellison syndrome)
Contraindications of Tolin Inj
- You are allergic to Pantoprazole, or any other proton pump inhibitors
- If you are allergic to any of the other ingredients of this medicine
- If you are on a medicine called Rilpivirine
Side effects of Tolin Inj
- Injection site inflammation that forms clot or block in the vein (thrombophlebitis)
- Nausea (feeling sick)
- Polyps in stomach
- Bloating and flatulence
- Dry mouth
- Stomach pain and discomfort
- Sleep disorders
- Skin rash, rash with fever, redness or inflamed skin, itchy skin
- Fracture of the hip, wrist or spine
- Lack of energy
Precautions and Warnings of Tolin Inj
Can I take Tolin Inj during pregnancy?
A moderate amount of data indicates that the use of Tolin Inj in pregnant women does not affect the baby; however this medicine is preferred to be avoided during pregnancy. If you are pregnant, you should use this medicine only if your doctor considers the benefit for you are more significant than the potential risk to your unborn baby.
Can I take Tolin Inj while breastfeeding?
Tolin Inj can pass into breast milk. It is advised not to take medicine unless prescribed by your doctor.
Can I drive if I have consumed Tolin Inj?
Tolin Inj has a negligible influence on the ability to drive. If you experience side effects like dizziness or disturbed vision, you should avoid driving or using machines.
Can I consume alcohol with Tolin Inj?
Drinking alcohol when you are taking Pantoprazole does not affect the way this medicine works; however, you must avoid drinking large quantities of alcohol as it is known to increase acidity and can make your acidity worse.
Other General Warnings
Talk to your doctor if
- You have severe liver problems
- You are taking NSAIDs (painkillers)
- You have a personal or family history of stomach cancer
- You are taking medicines used to treat HIV
- You have low levels of vitamin B12 (like Cobalamin). This medicine is known to reduce the absorption of vitamin B12 after a long term use.
- Taking this medicine for more than one year may increase chances of developing bone fractures
- If you are on this medicine for more than three months, your blood magnesium levels may drop. Your doctor may perform regular tests for the same
- On exposure to sun, you get rash on your skin, stop your treatment with Pantoprazole and inform your doctor as this may be a symptom of Subacute Cutaneous Lupus Erythematosus (SCLE)
Mode of Action of Tolin Inj
How Does It Work?
A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Pantoprazole binds to this proton pump in stomach cells, thus blocking acid secretion. Therefore, it is used in conditions where there is excessive acidity.
Directions for Use of Tolin Inj
- This medicine will be given in hospital by your doctor or nurse as an injection
- Do not self inject this medicine
Interactions of Tolin Inj
Interactions with other medicines
- Medicines that are gastric pH dependent such as Itraconazole, Ketoconazole (used to treat fungal infections)
- Medicines given in HIV or AIDS such as Atazanavir, Tenofovir
- Medicines used for thinning, or thickening of the blood like Warfarin and Phenprocoumon
- Medicines used for certain types of cancer such as Methotrexate
Interactions with food items
- There are no known interactions with food or beverages.
- However, nicotine and caffeine (coffee, tea, chocolate and cola) can increase stomach acid or delay ulcer healing and hinder the treatment process.
Storage and disposal of Tolin Inj
- Store below 25°C
- Protect it from direct sunlight
- Please keep it away from children
Dosage of Tolin Inj
Your doctor or nurse will give this injection; therefore, it is unlikley that you overdose on the medicine.
Missed a Dose
- Your doctor or nurse will monitor you about when the medicine should be given to you
- It is unlikely that the dose will be missed. However, if you think your doctor or nurse might have missed a dose, inform them
Frequently Asked Questions (FAQs)
Q: I get recurring acidity, what should I do to avoid it?
- Avoid spicy, oily food.
- Reduce smoking and alcohol intake as these are known to worsen the reflux.
- Avoid carbonated drinks like cold drinks, soda as the carbon dioxide gas in these is known to aggravate acid reflux.
- Reduce chocolate, mint intake.
- Some medicines are known to increase the acidity and worsen the condition such as pain killers, Ibuprofen. You should avoid using these for long duration.
Q: I have been given Pantoprazole for some months now, what should I watch for?
- This medicine will be given only for the duration as prescribed by your doctor.
- If there is relief in your symptoms, your doctor may reduce its dose.
- This medicine is known to cause fractures, low magnesium levels, vitamin B12 levels on long term use.
- You need to be cautious about these and keep checking your blood levels regularly, and if needed, your doctor may prescribe the supplements for these deficiencies.
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Last Updated on: 31 Jul 2020 | 07:00 PM (IST)
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