Tofe Tablet

• If you are allergic to tofacitinib or any other ingredient of the Tofe Tablet.
• If you have tuberculosis (TB), serious infections such as sepsis, or opportunistic infections (infections that occur more frequently and more severely in people with a weak immune system).
• If you have any kind of liver disease.
• If you are pregnant, planning to become pregnant, or breastfeeding.

• Headache
• Nausea
• Diarrhoea
• Cough
• Increase in blood pressure
• Infection and inflammation of the nose and throat

Other General Warnings

• You think you have an infection or have symptoms of an infection such as fever, sweating, chills, muscle pain, cough, difficulty breathing, weight loss, warm or red or painful skin or sores on your body, difficulty or pain when swallowing, diarrhoea, stomach pain, burning when you urinate or urinating more often than normal, feeling very tired.
• You already are taking medicines for any kind of infection or have infections that keep coming back.
• You have any condition that increases your chance of infection (diabetes, weak immune system).
• You have or have a history of tuberculosis or have been in close contact with someone with tuberculosis.
• You have any kind of lung disease, liver disease, kidney disease, or heart disease (high blood pressure, high cholesterol).
• You have or had hepatitis B or hepatitis C (viruses that affect the liver).
• You are older than 65 years.
• You currently smoke or used to smoke in the past.
• You have any type of cancer.
• You have had diverticulitis (a type of inflammation of the large intestine) or ulcers in the stomach or intestines.
• You are planning to get vaccinated soon.

• Take this medicine as a whole with sufficient water.
• Always take this medicine exactly as prescribed by your doctor.
• Do not consume more than the prescribed dose.
• Do not discontinue the medicine on your own without consulting your doctor.

• Store in a cool and dry place away from direct sunlight.
• Keep away from children and pets.

• Take Tofe Tablet at the same time every day for best results.
• Do not skip doses or stop the medicine without consulting your doctor.
• Stay alert for signs of infection and report them promptly.
• Drink plenty of water to stay hydrated.
• Avoid alcohol or limit its intake while on this medication.
• Follow a balanced diet and gentle exercise routine to support joint health.
• Inform your doctor about any other medicines or supplements you are taking.
• Monitor blood pressure and general health regularly, especially if you have other medical conditions.

Overdose

Missed a Dose

How Does It Work?

Interactions with other medicines

• Some medicines can affect the way the Tofe Tablet works, or the Tofe Tablet itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• Tofe Tablet when given along with ketoconazole, itraconazole, ritonavir, nefazodone, telithromycin increases the level of Tofe Tablet in the body.
• Tofe Tablet when given along with rifampicin decreases the level of Tofe Tablet in the body.
• Care should be taken when the Tofe Tablet is administered along with medicines like fluconazole, tacrolimus, and cyclosporine.

Interactions with food items

• No major food restrictions are reported with Tofe Tablet.
• Take the tablet with or without food as per your convenience.
• Avoid excessive alcohol consumption while on this medicine.
• Maintain a balanced diet to support overall immunity and joint health.
• Inform your doctor if you regularly consume grapefruit or grapefruit juice, as it may affect some medications (though specific effect on Tofe is not well-studied).