Tofe Tablet
By ALKEM LABORATORIES LTD
10 Tablet(s) in Strip
₹146.93
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₹195.90
25% OFF
₹14.69/tablet
(Inclusive of all taxes)
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Description
Tofe Tablet is a medicine used to treat rheumatoid arthritis, an inflammatory condition where your immune system attacks your joints, causing pain, swelling, and stiffness. It helps reduce joint discomfort and allows you to perform daily activities with less difficulty. This medicine contains tofacitinib, which works by controlling the overactive immune response that causes inflammation in rheumatoid arthritis.
Taking Tofe Tablet exactly as prescribed by your doctor is important for the best results. It should be taken at the same time every day, with enough water. Do not stop the medicine on your own, even if your symptoms improve, because this can affect the control of your condition. Always inform your doctor about any existing health problems, infections, or allergies before starting this medicine.
Tofe Tablet may take a few weeks to show improvements in symptoms, depending on the severity of your condition. While taking it, you may experience side effects such as headache, nausea, diarrhoea, cough, or an increase in blood pressure. Report any unusual symptoms to your doctor promptly. The medicine may also affect your immune system, so precautions should be taken to avoid infections.
Store Tofe Tablet in a cool, dry place away from sunlight and out of reach of children. If a dose is missed, take it as soon as you remember, but do not double the dose to make up for it. In case of an overdose, contact your doctor or visit the nearest hospital immediately. Always discuss any other medicines, supplements, or herbal products you are taking with your doctor to prevent possible interactions.
Product Summary
| Offer Price | ₹146.93 |
| You Save | ₹48.97 (25% on MRP) |
| Contains | Tofacitinib(5.0 Mg) |
| Uses | Rheumatoid arthritis |
| Side effects | Headache, nausea, diarrhoea, increase in blood pressure, infection and inflammation of the nose and throat |
| Therapy | DRUGS FOR RHEUMATOID ARTHRITIS |
Uses
Tofe Tablets are used for the treatment of rheumatoid arthritis in adults.
Contraindications
- If you are allergic to tofacitinib or any other ingredient of the Tofe Tablet.
- If you have tuberculosis (TB), serious infections such as sepsis, or opportunistic infections (infections that occur more frequently and more severely in people with a weak immune system).
- If you have any kind of liver disease.
- If you are pregnant, planning to become pregnant, or breastfeeding.
Side effects
- Headache
- Nausea
- Diarrhoea
- Cough
- Increase in blood pressure
- Infection and inflammation of the nose and throat
Precautions and Warnings
Pregnancy
Q:
Can I take Tofe Tablets during pregnancy?
A:
Limited information is available regarding the safety of Tofe Tablets in pregnant women. As a precautionary measure, the use of Tofe Tablets during pregnancy is contraindicated. Women of childbearing potential (women before menopause who are capable of becoming pregnant) should use effective contraceptive measures while on treatment with Tofe Tablets.
Breast Feeding
Q:
Can I take Tofe Tablets while breastfeeding?
A:
There is limited information available regarding the excretion of Tofe Tablets in human breastmilk. Thus, it is advised to avoid taking this medicine to prevent any risks to the breastfed child.
Driving
Q:
Can I drive if I have consumed Tofe Tablets?
A:
Tofe Tablets have no influence on the ability to drive. However, if you feel that you may not be able to drive safely after taking Tofe Tablets, it is suggested that you do not drive.
Alcohol
Q:
Can I consume alcohol with Tofe Tablets?
A:
There is limited information available regarding the interaction of alcohol with Tofe Tablets. Ask your doctor for advice on alcohol intake along with the Tofe Tablet.
Other General Warnings
Talk to your doctor if
- You think you have an infection or have symptoms of an infection such as fever, sweating, chills, muscle pain, cough, difficulty breathing, weight loss, warm or red or painful skin or sores on your body, difficulty or pain when swallowing, diarrhoea, stomach pain, burning when you urinate or urinating more often than normal, feeling very tired....
- You already are taking medicines for any kind of infection or have infections that keep coming back.
- You have any condition that increases your chance of infection (diabetes, weak immune system).
- You have or have a history of tuberculosis or have been in close contact with someone with tuberculosis.
- You have any kind of lung disease, liver disease, kidney disease, or heart disease (high blood pressure, high cholesterol).
- You have or had hepatitis B or hepatitis C (viruses that affect the liver).
- You are older than 65 years.
- You currently smoke or used to smoke in the past.
- You have any type of cancer.
- You have had diverticulitis (a type of inflammation of the large intestine) or ulcers in the stomach or intestines.
- You are planning to get vaccinated soon.
Directions for Use
- Take this medicine as a whole with sufficient water.
- Always take this medicine exactly as prescribed by your doctor.
- Do not consume more than the prescribed dose.
- Do not discontinue the medicine on your own without consulting your doctor.
Storage and disposal
- Store in a cool and dry place away from direct sunlight.
- Keep away from children and pets.
Quick Tips
- Take Tofe Tablet at the same time every day for best results.
- Do not skip doses or stop the medicine without consulting your doctor.
- Stay alert for signs of infection and report them promptly.
- Drink plenty of water to stay hydrated.
- Avoid alcohol or limit its intake while on this medication.
- Follow a balanced diet and gentle exercise routine to support joint health.
- Inform your doctor about any other medicines or supplements you are taking.
- Monitor blood pressure and general health regularly, especially if you have other medical conditions.
Dosage
Overdose
Symptoms of overdose of Tofe Tablet include headache, nausea, and diarrhoea. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
You should never miss your dose of medicines. However, if you missed any dose of the medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one....
Mode of Action
How Does It Work?
Tofe Tablet works by blocking the action of a certain chemical in the body known as Janus kinase. This chemical plays an important role in the process of inflammation in rheumatoid arthritis. By blocking the action of this chemical, the Tofe Tablet helps to reduce inflammation, pain, and discomfort that occurs in rheumatoid arthritis....
Interactions
Interactions with other medicines
- Some medicines can affect the way the Tofe Tablet works, or the Tofe Tablet itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Tofe Tablet when given along with ketoconazole, itraconazole, ritonavir, nefazodone, telithromycin increases the level of Tofe Tablet in the body.
- Tofe Tablet when given along with rifampicin decreases the level of Tofe Tablet in the body.
- Care should be taken when the Tofe Tablet is administered along with medicines like fluconazole, tacrolimus, and cyclosporine.
Interactions with food items
- No major food restrictions are reported with Tofe Tablet.
- Take the tablet with or without food as per your convenience.
- Avoid excessive alcohol consumption while on this medicine.
- Maintain a balanced diet to support overall immunity and joint health.
- Inform your doctor if you regularly consume grapefruit or grapefruit juice, as it may affect some medications (though specific effect on Tofe is not well-studied).
Content Details
WRITTEN BY
Dr. Mansi Savla
B. Pharm, PharmD
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What is rheumatoid arthritis and what are its signs and symptoms?
A: Rheumatoid arthritis is an inflammatory disease where your immune system attacks your own body's tissues and causes swelling, pain, and discomfort in your joints. Rheumatoid arthritis is a long-term disease and the signs and symptoms of the disease include pain, swelling, & stiffness in one or more joints, weight loss, fever, tiredness, and weakness.
Q: How long does it take for Tofe Tablet to work?
A: Tofe Tablet starts working as soon as you start with the treatment . However, the improvement in your symptoms might take a few weeks depending on the severity of your condition and its physiology. Talk to your doctor for more infromation.
Q: Does Tofe Tablet cause changes in weight?
A: No, Tofe Tablet does not have weight gain or weight loss as common side effect. However, if you think you are experiencing changes in weight, talk to your doctor.
Q: Is hair loss a side effect of the Tofe Tablet?
A: No, hair loss was not reported as a side effect of taking Tofe Tablets. If you have any concerns about hair loss while taking this medicine, talk with your doctor.
Q: Is Tofe Tablet an anti-inflammatory medicine?
A: Tofe Tablet is an anti-rheumatoid medicine that is used to reduce the signs and symptoms of rheumatoid arthritis. Tofe Tablet reduces the inflammation of the joints that occurs because of rheumatoid arthritis.
Q: Will my immune system be suppressed if I take Tofe Tablets?
A: Rheumatoid arthritis is an inflammatory disease where your immune system attacks your own body's tissues and causes swelling, pain, and discomfort in your joints. Tofe Tablet is an anti-inflammatory immunosuppressant medicine that reduces the activity of the immune system. This reduction in activity reduces the pain, swelling, and discomfort of the joints in rheumatoid arthritis.
References
View All
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 28 Aug 2025]
- XELJANZ 5 mg film-coated tablets [Internet]. Ema.europa.eu. 2025 [cited 28 Aug 2025]
- Xeljanz (tofacitinib) [Internet]. Ema.europa.eu. 2025 [cited 28 Aug 2025]
- XELJANZ 5mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 28 Aug 2025]
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Product Details
Brand
TOFE
Address
ALKEM HEALTH SCIENCE A Unit of Alkem Laboratories Limited, Unit-2, Samardung, Karek Block, P.O.: Namthang, District - Namchi, Sikkim-737 137.
Country of Origin
India
Expiry Date
30/10/2027
Manufacturer Details
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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