Rzole DSR Capsule
Description
Rzole DSR Capsule is a combination medicine used to manage acid reflux and related gastrointestinal problems. It contains domperidone, which improves stomach motility, and omeprazole, which reduces excess stomach acid. Together, these ingredients help alleviate symptoms such as heartburn, chest discomfort, and nausea associated with acid reflux.
This capsule is typically prescribed to patients with gastroesophageal reflux disease (GERD) or other conditions where stomach acid flows back into the oesophagus, causing irritation. Rzole DSR works by both reducing acid production in the stomach and speeding up the movement of food, thereby preventing the backflow of acid.
Take Rzole DSR Capsule exactly as prescribed by your doctor, typically before meals for optimal results. Swallow the capsule whole with a glass of water. Do not crush or chew the capsule, as it may reduce the effectiveness of the medicine. Always follow the dosage and duration recommended by your healthcare provider.
Common side effects of Rzole DSR Capsule may include diarrhoea, dry mouth, headache, constipation, and fatigue. These side effects are generally mild and temporary. If you experience persistent or severe side effects, consult your doctor immediately. Avoid self-medicating or adjusting the dose without consulting a doctor.
Before starting Rzole DSR Capsule, inform your doctor about your complete medical history, including any liver or kidney problems, allergies, or ongoing medications. Pregnant or breastfeeding women should take this medicine only under medical supervision. Following your doctor’s instructions and maintaining a healthy lifestyle can help maximise the benefits of this treatment.
Product Summary
Offer Price | ₹97.16 |
You Save | ₹73.30 (43% on MRP) |
Contains | Rabeprazole(20.0 Mg)+Domperidone(30.0 Mg) |
Uses | Gastrointestinal reflux disease |
Side effects | Diarrohea, dry mouth, headache, constipation and fatigue |
Therapy | ANTACID AND ANTI-EMETIC |
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Uses
Contraindications
- If you are allergic to omeprazole and domperidone, any of the ingredients of Rzole DSR capsule.
- If you have low magnesium levels in your blood.
- If you have stomach or intestinal bleeds or obstruction.
- If you are suffering from liver or kidney disorder.
- If you have problems related to bones like osteoporosis and had a fracture.
- If you have serious heart problems like congestive heart failure, heart rhythm problems, etc.
- If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
Side effects
- Dizziness
- Headache
- Dry mouth
- Loose stool
- Stomach pain
- Lack of sleep
- Rashes
- Giddiness
- Skin rash
Precautions and Warnings
Pregnancy
- The components of Rzole DSR capsule might harm your unborn baby.
- This medicine should not be used during pregnancy.
- Consult your doctor if you are pregnant or think you may be pregnant or planning to have a baby.
Breast Feeding
Driving
Alcohol
Other General Warnings
Directions for Use
Storage and disposal
- Store Rzole DSR capsules below 25°C, protected from moisture.
- Keep the medicine out of the reach of children and pets.
- Any medicine that has passed its expiry date or is unused for a long time should be disposed off appropriately.
Quick Tips
- Take Rzole DSR Capsule exactly as prescribed by your doctor.
- Swallow the capsule whole with a glass of water; do not crush or chew it.
- It is best taken before meals for optimal results.
- Avoid spicy, oily, and acidic foods while on this medicine to reduce acid reflux.
- Do not stop taking the medicine suddenly, even if symptoms improve.
- Drink plenty of water and maintain a healthy lifestyle to support treatment.
- Report any persistent side effects like diarrhoea, constipation, headache, or fatigue to your doctor.
- Inform your doctor about any liver, kidney, or heart conditions before starting the medicine.
- Pregnant or breastfeeding women should take this medicine only under medical supervision.
- Continue to follow up on appointments to monitor progress and adjust the dose as necessary.
Dosage
Overdose
- Overdose can result in confusion, dizziness, nausea or headache.
- In case of an overdose, visit your nearest hospital or contact your doctor.
Missed a Dose
- If you missed any dose of Rzole DSR, take it as soon as you remember it.
- If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule.
- Do not take a double dose of medicine to compensate for the missed one.
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
Interactions with food items
Content Details

Dr. Arpit Verma
MBBS, MD, CCEBDM Diabetology

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Is there any danger of taking cap Rzole DSR for too long?
- Yes, taking any medicine for too long or in too much quantity has its side effects.
- This medicine should only be taken for the duration as prescribed by your doctor, do not self-medicate yourself.
- In long-term use, this medicine is known to cause low levels of magnesium, increased fracture risk and vitamin B12 deficiency.
- Your doctor may monitor you for these when on long term treatment.
Q: Does smoking and alcohol increase acidity and GERD?
Q: Can I feel constipated on taking capsule Rzole DSR ?
Q: Does Rzole capsule lead to weight gain?
Q: Can we take Rzole DSR after food?
Q: What is the composition of Rzole DSR?
Q: What is Rzole DSR used for?
Q: What are the side effects of Rzole DSR?
References
- Omeprazole 40mg Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 15 April 2022]
- Omeprazole 40mg Capsules - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 15 April 2022]
- Domperidone 10mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 15 April 2022]
- Domperidone 10mg Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 15 April 2022]
- Shahani S, Sawant P, Dabholkar P. Rabeprazole plus domperidone: the answer for gastro-oesophageal reflux disease. J Indian Med Assoc. 2008 Apr;106(4):264, 266, 268. PMID: 18828350.[cited 13 Feb 2025]
- Ramadan NK, Mohamed HM, Moustafa AA. Simultaneous determination of Rabeprazole sodium and Domperidone. J Appl Pharm Sci. 2025 [cited 13 Feb 2025]
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