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Petril Plus Tablet

10 Tablet(s) in Strip
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Petril Plus Tablet Description

Petril Plus Tablet is recommended to treat and maintain depression and anxiety. It is a combination of two medications, clonazepam and escitalopram, which act on the chemical messengers in the brain.

Both the active ingredients enhance the function of certain substances and decrease the activity of other substances to bring about a calming effect and improve the mood by maintaining a healthy mental balance. The medication may be addictive and sudden discontinuation of the treatment may lead to withdrawal symptoms. Your physician will gradually taper and reduce the dose instead of suddenly discontinuing the medication. It is also recommended to resume the previous dose if there are worsening symptoms due to a decrease in the dose and then continue to taper and wean off at a much slower rate. It is essential for family and other people involved in the patient’s care to be vigilant to unusual behavioural changes, worsening symptoms, suicidal behaviour during treatment with antidepressants. Close observation and monitoring are required, especially during the first few months of starting the therapy. If it is observed that the symptoms of depression are worsening or there are any new suicidal thoughts or ideas, or other symptoms that may lead to further worsening of depression or suicidality, then changing the treatment modality and discontinuation of the medication should be considered, especially if the patient did not have any such symptoms at the time of treatment onset.


Product Summary

Offer Price₹148.69
You Save₹24.21 (14% on MRP)
ContainsClonazepam(0.5 Mg) + Citalopram(10.0 Mg)
UsesTreatment of depression and anxiety disorder
Side effectsNausea, palpitations, weakness, headache, confusion, anxiety, difficulty with sleep/sleep disturbances, sexual problems
Check more medicines with composition as Clonazepam(0.5 Mg) + Citalopram(10.0 Mg)

Uses of Petril Plus Tablet

  • Treatment of depression and anxiety disorder.

Contraindications of Petril Plus Tablet

Current treatment with antidepressants (Monoamine oxidase inhibitors) or use in the last 14 days. Concomitant use with Pimozide (used in the treatment of psychosis). Allergic to any of the substance...
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Side effects of Petril Plus Tablet

  • Nausea
  • Palpitations
  • Weakness
  • Headache
  • Confusion
  • Anxiety
  • Difficulty with sleep/sleep disturbances
  • Sexual problems

Precautions and Warnings of Petril Plus Tablet



Can I take Petril Plus during pregnancy?
No, you should not take Petril Plus during pregnancy as it can affect the growing baby. Petril Plus should be used during pregnancy only after medical consultation with your doctor. While on treatment with the medication, please inform your doctor immediately if you get pregnant.

Breast Feeding

Can I take Petril Plus while breastfeeding?
Petril Plus may be passed into the breast milk. Please consult your doctor before use while you are breastfeeding.


Can I drive if I have taken Petril Plus?
It is recommended to avoid driving until you know how the medication affects you. Judgement, thinking, or motor skills may be affected by the use of this medication.


Can I consume alcohol with the Petril Plus tablet?
It is recommended to avoid alcohol when taking Petril Plus as alcohol may amplify the side effects of the medication.

Other General Warnings

Talk to your doctor if
  • If you are already taking escitalopram, citalopram, or clonazepam
  • If you have liver problems
  • If you have kidney problems
  • If you have any heart problems, high blood pressure, or a history of stroke
  • If you have any eye problems ( glaucoma or increased pressure in the eye)
  • If you have or had seizures
  • If you have low sodium blood levels
  • If you have any bleeding problems
  • If you are on any other medications, vitamins, supplements, herbal supplements which could potentially cause medication interactions and other side effects

Mode of Action of Petril Plus Tablet

How Does It Work?

Petril Plus is a combination of two active ingredients. Clonazepam is thought to work by improving the activity of a certain chemical messenger (gamma-aminobutyric acid) in the brain, which blocks imp...
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Directions for Use of Petril Plus Tablet

  • Petril Plus should be taken exactly as prescribed by the doctor.
  • Take the tablet whole.
  • Follow the directions correctly.
  • The medication may be taken with or without food.

Interactions of Petril Plus Tablet

Interactions with other medicines

  • Medications that interfere with the chemical substance (serotonin) in the brain, such as antidepressants, linezolid and intravenous methylene blue.
  • Medications such as fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. John’s Wort.
  • Medications to treat heartburn and acid reflux such as omeprazole, esomeprazole, fluvoxamine, lansoprazole, ticlopidine.
  • Medicines used for pain relief (Nonsteroidal anti-inflammatory medicines (NSAIDs).
  • Aspirin
  • Warfarin or other medications used for thinning the blood.
  • Triptans used to treat migraine headaches.
  • Medications such as carbamazepine (treat fits), lithium (treat episodes of mania in bipolar disorder)

Storage and disposal of Petril Plus Tablet

Petril Plus should be stored in a cool, dry place. It should not be used after the expiry date mentioned in the box. Expired or unneeded medication should be disposed of appropriately as biomedical wa...
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Dosage of Petril Plus Tablet


  • Symptoms of overdose most often include convulsions, coma, dizziness, low blood pressure, nausea, vomiting, fast-beating heart, excessive sleepiness. Please contact your physician immediately or the n...
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Missed a Dose

In case you miss a dose of Petril Plus, then take the missed dose as soon as you remember. If it is nearing the next dose’s time, skip the missed dose and continue with the next dose at the regular ti...
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Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Is Petril Plus safe for use in children?

A: It is not recommended for use in paediatric patients less than 12 years.

Q: When is it safe to discontinue therapy with Petril Plus?

  • Even though you may notice improvement within a few weeks of starting therapy, you should continue therapy as directed until the treating physician deems it necessary and starts you on a medication we...
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Product Details
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Last Updated on: 10 Feb 2022 | 09:31 AM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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