Express delivery to
Select Pincode
Search for Medicine and Healthcare items
Search
medicine

Pentothal Sodium 1gm Injection 1'S

By PFIZER LTD
1 Injection(s) in Vial
We do not sell this product
All the Products are packed and stored Safely

Pentothal 1 GM Description

Pentothal Sodium Injection is used for general anaesthesia. It can be used to lower intracranial pressure as well. Pentothal Sodium 1gm Injections are given under the supervision of a healthcare pra

ctitioner in a hospital setting. It's crucial to share your medical history and let your doctor know if you have heart disease, asthma, or myasthenia gravis. This medication requires extra caution when administered to these people. Side effects of Pentothal Sodium 1gm Injection include skin rash or pain at the injection site and nausea, vomiting, diarrhoea, and vertigo. Because it may produce dizziness and fatigue, do not drive or do anything that requires mental focus while taking it. You should avoid drinking alcohol or taking other sleepy drugs after taking this prescription since it may cause serious side effects. You should utilise additional pregnancy prevention strategies because this medication may diminish the effectiveness of birth control tablets.

modeOfAction

Product Summary

Offer Price₹39.10
You Save₹6.90 (15% on MRP)
ContainsThiopentone / Thiopental / Penthiobarbital(1.0 Gm)
UsesAnaesthesia
Side effectsDrowsiness, Skin Rash, Nausea, Vomiting, Diarrhoea, Vertigo
TherapyGENERAL ANAESTHESIA
molecules
Check more medicines with composition as Thiopentone / Thiopental / Penthiobarbital(1.0 Gm)
uses

Uses of Pentothal 1 GM

  • Anaesthesia
contraindications

Contraindications of Pentothal 1 GM

  • Allergy
  • You should not use this drug if you have a known allergy to Pentothal Sodium or any other inactive ingredients in the formulation.
  • Respiratory depression
  • This injection is not recommended for patients with respiratory depression due to the increased risk of the patient's condition worsening.
  • Porphyria
  • This injection is not recommended for porphyria patients due to the higher risk of the patient's condition worsening.
  • Myasthenia gravis
  • This injection is not recommended for people with myasthenia gravis since it increases the chance of the patient's condition worsening.
  • Severe anaemia
  • This injection is not recommended for use in patients with severe anaemia due to the increased risk of the patient's condition worsening.
sideEffects

Side effects of Pentothal 1 GM

  • Drowsiness
  • Skin Rash
  • Nausea
  • Vomiting
  • Diarrhoea
  • Vertigo
precautionsAndWarnings

Precautions and Warnings of Pentothal 1 GM

pregnancy

Pregnancy

Q:
Can I take Pentothal Sodium 1gm Injection during pregnancy?
A:
Using injections while pregnant can be risky. Despite the absence of human studies, animal research has shown harmful effects on the developing foetus. Your doctor will weigh the benefits and any potential risks before recommending them to you. Please consult a physician.
breastfeeding

Breast Feeding

Q:
Can I take Pentothal Sodium 1gm Injection while breastfeeding?
A:
Pentothal Sodium 1gm Injection is safe to use when nursing. According to human research, the medicine does not pass substantial amounts into breastmilk and does not harm the baby.
driving

Driving

Q:
Can I drive if I have taken Pentothal Sodium 1gm Injection 1'S?
A:
Pentothal Sodium 1gm Injection may have side effects that make driving difficult.
alcohol

Alcohol

Q:
Can I consume alcohol with the Pentothal Sodium 1gm Injection?
A:
If you drink alcohol while taking Pentothal, you may experience dizziness and sleepiness (thiopental). Because both alcohol and Pentothal depress the central nervous system, the two together are significantly more dangerous; thus, avoid all alcohol use while preparing for a Pentothal injection.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • If you have heart disease- Due to worsening the patient's condition, this medicine should be used with caution in patients with heart disease. In some situations, dependent on the clinical condition o...
    Read more
  • If you have thyroid disorders-Because of the danger of worsening the patient's condition, this medicine should be used with caution in patients with thyroid problems. In some situations, dependent on ...
    Read more
  • If you have Hypovolemia-Due to the potential of worsening the patient's condition, this medicine should be used with caution in patients with a low level of fluids in the body. In some situations, dep...
    Read more
  • If you have hypotension-Patients receiving this injection for anaesthesia should be continuously watched for evidence of severe hypotension (low blood pressure) or heart depression. Appropriate remedi...
    Read more
modeOfAction

Mode of Action of Pentothal 1 GM

How Does It Work?

It works by inducing reversible loss of consciousness, allowing surgery to be performed without pain or discomfort.
directionsForUse

Directions for Use of Pentothal 1 GM

  • Your doctor or nurse will administer this medication to you. Please refrain from self-medicating.
interactions

Interactions of Pentothal 1 GM

Interactions with other medicines

  • Gastrointestinal medicines like Metoclopramide and droperidol reduce the dose of Pentothal Sodium required to induce anaesthesia.
  • Using anaesthetics with other CNS depressant medicines such as those used for premedication may produce synergistic effects on the CNS. In some cases, a smaller dose of general anaesthetic should be u...
    Read more
  • Benzodiazepines such as midazolam potentiate the anaesthetic effects of Pentothal Sodium.
  • Pretreatment with probenecid has been shown to potentiate Pentothal Sodium anaesthesia.
  • The enhanced hypotensive effects are seen when general anaesthetics are given with angiotensin-II receptor antagonists like Eprosartan, Irbesartan, Losartan, Olmesartan, Telmisartan
  • Hypersensitivitylike reactions can occur when general anaesthetics are given with intravenous vancomycin.
  • Increased risk of arrhythmias and hypotension when general anaesthetics are given with tricyclic antidepressants. Hypotension and hypertension have been seen with MAOIs.
  • The enhanced hypotensive effect may be seen when Pentothal Sodium is given with diazoxide.
  • The enhanced hypotensive effect may be seen when Pentothal Sodium is given with diuretics.
  • The enhanced hypotensive effect may be seen when Pentothal Sodium is given with methyldopa.
  • Moxonidine: Enhanced hypotensive effect when Pentothal Sodium is given with moxonidine
  • Nitrates: Enhanced hypotensive effect when given with nitrates.Vasodilator antihypertensives: Enhanced hypotensive effect when general anaesthetics given with hydralazine, minoxidil or nitroprusside.
  • It should be noted that Pentothal Sodium will interact with beta-blockers and calcium antagonists, causing a fall in blood pressure.
  • The enhanced hypotensive effect is seen with ACE inhibitors when Pentothal Sodium is given.
  • Adrenergic neuron blockers: Enhanced hypotensive effect when Pentothal Sodium is given with adrenergic neurone blockers such as guanoxan, guanclofine and guanethidine.
  • The enhanced hypotensive effect may be seen when Pentothal Sodium is given with alpha-blockers.
  • Animal data suggest valerian and St John's Wort may prolong the effect of Pentothal Sodium.
  • Pretreatment with aspirin has been shown to potentiate Pentothal Sodium anaesthesia
  • Opioids potentiate the respiratory depressive effect. The effect is enhanced by alcohol, hypnotics, centrally acting muscle relaxants, anxiolytics, antipsychotics and antihistamines.

Interactions with food items

  • Pentothal's effects may persist longer than usual if you take St. John's wort. As a result, it should be avoided before any procedure that requires general anaesthesia or before any other usage of Pen...
    Read more
storageAndDisposal

Storage and disposal of Pentothal 1 GM

Keep it in an airtight container at a controlled room temperature (15° to 30°C). Before opening: There are no particular storage requirements for the therapeutic product. Refrigerate for up to 24 hour...
Read more
dosage

Dosage of Pentothal 1 GM

Overdose

Because this medicine is provided in a hospital setting by a qualified healthcare provider, the chance of an overdose is relatively minimal. However, the doctor will begin immediate medical treatment ...
Read more

Missed a Dose

Because this medication is usually administered by a competent healthcare provider before and during a surgical procedure in a clinical/hospital setting, the chances of missing a dose are slim.

Content Details

WRITTEN BY
doctor

Dr. Shreya Aggarwal

Bachelor of Dental Surgery

REVIEWED BY
doctor

Dr. Vijay Y

MBBS, MD in Clinical Pharmacology

Frequently Asked Questions (FAQs)

^

Q: Is Pentothal Sodium toxic?

A: Pentothal Sodium is always administered intravenously. It can be fairly irritating to tissue and a vesicant; severe tissue necrosis and sloughing can occur if it is injected incorrectly into the tissue around a vein.

Q: How long does it take for Sodium Pentothal to work?

A: Pentothal (Thiopental Sodium for Injection, USP) is an ultra-short-acting central nervous system depressant that causes hypnosis and anaesthesia but not analgesia. Within 30 to 40 seconds after intravenous infusion, it induces hypnosis.

Q: How long does anaesthesia stay in your urine?

A: Anesthetic injections might last up to 24 hours in your system. If you've received sedation or regional or general anaesthesia, you shouldn't drive or return to work until the medicine has passed through your system.
Product Details
Brand
PENTOTHAL
Expires on or After
02/03/2023

Other Products from this Brand

Last Updated on: 25 Apr 2022 | 11:29 AM (IST)
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
Our Payment Partners
https://assets.pharmeasy.in/web-assets/_next/icons/gpay.svg
https://assets.pharmeasy.in/web-assets/_next/icons/paytm.svg
https://assets.pharmeasy.in/web-assets/_next/icons/amazon-pay.svg
https://assets.pharmeasy.in/web-assets/_next/icons/phonepe.svg
https://assets.pharmeasy.in/web-assets/_next/icons/mobikwik.svg
https://assets.pharmeasy.in/web-assets/_next/icons/airtel-money.svg
https://assets.pharmeasy.in/web-assets/_next/icons/ola-money.svg
https://assets.pharmeasy.in/web-assets/_next/icons/maestro.svg
https://assets.pharmeasy.in/web-assets/_next/icons/mastercard.svg
https://assets.pharmeasy.in/web-assets/_next/icons/visa.svg
https://assets.pharmeasy.in/web-assets/_next/icons/rupay.svg
https://assets.pharmeasy.in/web-assets/_next/icons/diners.svg