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Loxet 20mg Tablet

10 Tablet(s) in Strip
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Loxet 20 MG Description

Loxet 20 mg tablet is used to treat depression, anxiety disorder, neuropathic pain, fibromyalgia, diabetic nerve pain, and stress urinary incontinence. The active ingredient in Loxet 20 mg tablets is

Duloxetine, which works by increasing the levels of chemical messengers, like serotonin and noradrenaline. These are natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain. Depression is a medical health condition that causes constant negative thoughts that affect your everyday life. Neuropathic pain is a condition caused by damage/injury to the nerves. This results in pain, weakness, tingling/burning sensation in the affected area. Anxiety disorder is a mental health disorder characterised by feelings of worry, anxiety, or fear that are strong enough to interfere with the affected person’s daily life. Fibromyalgia is characterised by widespread pain and tenderness (sensitivity to touch). Diabetic nerve pain damages the nerves that send signals from the hands and feet. Diabetic neuropathy can cause numbness or tingling in your fingers, toes, hands, and feet. Urinary incontinence is when the affected person leaks urine by accident. Directions for use of Loxet 20 mg tablets should be strictly followed. The course of treatment should be completed before stopping. The doctor should be informed about the user’s medical history and if they are taking any new medicines - this is to check for any medicine interactions. This medicine should be taken at a fixed time every day so a stable level of medication is maintained in the body. It may be taken at night if it causes sleepiness. Side effects of Loxet 20 mg tablets include nausea, dry mouth, headache, dizziness, sleepiness, colitis, liver damage, sexual dysfunction. It can cause serious symptoms like coma, serotonin syndrome, seizures, syncope, tachycardia, hypotension, hypertension, and vomiting in case of a Loxet 20 mg tablet overdose.


Product Summary

Offer Price₹67.94
You Save₹11.06 (14% on MRP)
ContainsDuloxetine(20.0 Mg)
UsesDepression, Anxiety disorder, Neuropathic pain, Fibromyalgia, Diabetic nerve pain and stress, Urinary incontinence
Side effectsNausea, Dry mouth, Headache, Dizziness, Sleepiness, Colitis, Liver damage, Sexual dysfunction
Check more medicines with composition as Duloxetine(20.0 Mg)

Uses of Loxet 20 MG

  • Loxet 20 mg tablets are used to treat:
  • Depression
  • Anxiety disorder
  • Neuropathic pain
  • Fibromyalgia
  • Diabetic nerve pain
  • Stress urinary incontinence

Contraindications of Loxet 20 MG

  • Do not take Loxet 20 mg tablets or use caution:
  • If you have low blood sodium levels.
  • If you have an increased risk of bleeding.
  • If you have manic behaviour.
  • If you have a form of mania with lower severity of symptoms.
  • If you have manic-depression.
  • If you have suicidal thoughts.
  • If you have been diagnosed with syndrome of inappropriate antidiuretic hormone (SIADH) (a disorder with excess antidiuretic hormone)

Side effects of Loxet 20 MG

  • Side effects of Loxet 20 mg tablets include:
  • Nausea
  • Dry mouth
  • Headache
  • Dizziness
  • Sleepiness
  • Colitis
  • Liver damage
  • Sexual dysfunction

Precautions and Warnings of Loxet 20 MG



Can I take Loxet 20 mg tablets during pregnancy?
This medicine comes under Category-C medication and does not show major teratogenic effects on the foetus. But it is associated with an increased risk of postpartum haemorrhage and a small risk of cardiac malformations. Discuss your case with the doctor if you conceive during treatment with Loxet 20 mg tablets.

Breast Feeding

Can I take Loxet 20 mg tablets while breastfeeding?
Yes. A very small amount of this medicine passes into breast milk. Infant exposure to duloxetine in breast milk is less than 1% of the maternal weight-adjusted dose. This suggests that duloxetine can be safely administered to a woman breastfeeding her infant.


Can I drive if I have taken Loxet 20 mg tablets?
Some people can develop dizziness or drowsiness after taking this medicine. Do not drive, work on heavy machines, or do anything that requires mental focus with this medicine. Talk to your doctor about your work profile.


Can I consume alcohol with Loxet 20 mg tablets?
Alcohol consumption is prohibited during Loxet 20 mg tablets treatment as the combined effect can cause more drowsiness and sleepiness.

Other General Warnings

Talk to your doctor if
  • You conceive.
  • You plan to breastfeed.
  • You bleed or bruise easily.
  • You experience confusion.
  • You experience changes in sexual ability.
  • You experience decreased interest in sex.
  • You experience muscle cramps/weakness.
  • You experience shaking (tremor).
  • You experience difficulty urinating.
  • You show signs of liver problems, such as nausea, stomach/abdominal pain, vomiting, yellowing eyes/skin, and dark urine.

Mode of Action of Loxet 20 MG

How Does It Work?

Duloxetine works by increasing the levels of chemical messengers (serotonin and noradrenaline). These are natural substances in the brain that help maintain mental balance and stop the movement of pai...
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Directions for Use of Loxet 20 MG

  • Take Loxet 20 mg tablets exactly as advised by your doctor.
  • Do not exceed the dosage, even if you cannot notice the effects of this medicine.
  • Take Loxet 20 mg tablets as a whole with a glass of water.
  • Do not break or chew this tablet.
  • Take Loxet 20 mg tablets at the same time every day so a stable level of the medication is maintained in the body.
  • Your doctor might advise you to take Loxet 20 mg tablets at night if they make you sleepy.

Interactions of Loxet 20 MG

Interactions with other medicines

  • Loxet 20 mg tablets can interact with many medicines and cause adverse side effects. Taking these medicines with Loxet 20 mg tablets can cause adverse symptoms like extreme drowsiness, bleeding, heada...
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  • Antiplatelet drugs like clopidogrel
  • Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen
  • Blood thinners like warfarin and aspirin
  • Medicines like cimetidine, viloxazine, and certain quinolone
  • Antibiotics like ciprofloxacin and enoxacin
  • Antiarrhythmic drugs like propafenone, flecainide, and quinidine
  • Antipsychotics like thioridazine
  • Antidepressants like desipramine and imipramine
  • Monoamine oxidase inhibitors (MAOIs) like isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine
  • Antihistamines like cetirizine and diphenhydramine
  • Medicine for sleep or anxiety, like alprazolam, diazepam, and zolpidem
  • Muscle relaxants and opioid pain relievers like codeine
  • Cough-and-cold medication like Codral, Coldrex, Benadryl
  • Antidepressants like SSRIs (fluoxetine and paroxetine), other SNRIs (desvenlafaxine and venlafaxine), and tryptophan

Interactions with food items

  • Avoid grapefruit juice when on treatment with Loxet 20 mg tablets, as it can cause dizziness when taken with this medicine.

Storage and disposal of Loxet 20 MG

Store Loxet 20 mg tablets at room temperature in an airtight container, away from the reach of children and pets. Keep Loxet 20 mg tablets away from direct sunlight, heat, and moisture. Keep your tabl...
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Dosage of Loxet 20 MG


Loxet 20 mg tablet overdose can lead to coma, serotonin syndrome, seizures, syncope, tachycardia, hypotension, hypertension, and vomiting. Please consult your doctor immediately in case of an overdose...
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Missed a Dose

If you have missed a dose of Loxet 20 mg tablet, try to take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with yo...
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Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: Will excessive consumption of Loxet 20 mg tablets cause any side effects?

A: High doses of Loxet 20 mg tablets are dangerous. You can experience slurred speech, bloodshot eyes, significant weight loss, reduced appetite, sleeping too much or too little.

Q: How long will it take for Loxet 20 mg tablets to start working?

A: You may experience improvement in sleep, energy, and appetite within the first 1-2 weeks of treatment. This is an indication that the medicine is working. It may take about 6-8 weeks for an improvement in depression.

Q: Will my weight increase during treatment with this medicine?

A: Yes. Antidepressants interfere with neurotransmitters, like serotonin or histamine, in the brain, which helps control appetite. Blocking histamine may also boost appetite and result in weight gain.
Product Details
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Last Updated on: 04 Apr 2022 | 09:52 AM (IST)

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