Janumet 50/500mg Tablet
15 Tablet(s) in StripMRP ₹386.50
₹289.88
25% OFF
Made by
ABBOTT HEALTHCARE PVT LTD
Dosage
TABLET
Expiry
Product Summary
| Uses | Type 2 Diabetes mellitus |
| Therapy | Anti-diabetic |
| Side effects | Nausea, runny nose, headache, sore throat, flatulence |
| Salt Content | Metformin Hydrochloride(500.0 Mg)+Sitagliptin(50.0 Mg) |
Assurance
available
Regulated
Medical Description
Janumet 50/500mg Tablet is used alongside diet and exercise to control blood sugar in adults with type 2 diabetes when a single medicine is not enough. It contains sitagliptin and metformin, which lower glucose through two separate mechanisms.
Metformin reduces the glucose the liver releases and improves how well muscle responds to insulin. Sitagliptin blocks the enzyme DPP-4, protecting the gut hormones that prompt the pancreas to release insulin after a meal and reduce glucagon, so insulin is released only when glucose is actually rising.
Take it twice daily with or immediately after food, which substantially reduces the nausea, metallic taste and loose stools metformin can cause. Do not stop when your readings improve; that improvement is the treatment working.
Seek urgent medical attention for severe persistent upper abdominal pain spreading to the back, which may indicate pancreatitis, or for unusual muscle pain, rapid breathing and extreme tiredness, which may indicate the rare complication lactic acidosis.
Kidney function must be checked before starting and at least yearly, and the medicine stopped before contrast scans and surgery. Long-term metformin lowers vitamin B12, so levels should be monitored periodically.
Istamet 50/500mg tablet, Sitazor 50/500mg tablet and Glura M 500mg tablet are a few more tablets that also contain sitagliptin and metformin.
Uses
Contraindications
- If you are allergic to sitagliptin, metformin or any other ingredients of Janumet tablet.
- If you have severe kidney or liver disease.
- If your diabetes is not under control and you also have high blood sugar, nausea, vomiting, loose motions, rapid loss of weight, pain in the stomach, breathing difficulty, sleepiness, etc.
- If you have dehydration or you have the presence of severe infection.
- If you have to go to do an x-ray or scan dye is injected in your blood before doing the x-ray or scan.
- If you have a recent history of a heart attack.
- If you are a heavy alcohol drinker.
- If you are a lactating mother.
Side effects
- Nausea
- Vomiting
- Stomach pain
- Diarrhoea
- Constipation
- Flatulence (gas)
- Low blood sugar
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have a skin blister after taking this medicine.
- You have a fever, vomiting, loose motion, heat exposure, and less fluid intake.
- You have vomiting, pain in the stomach, breathing difficulty, tiredness, muscle cramps, decreased body temperature, and decreased heartbeat after taking this medicine.
- You have low blood sugar after taking other anti-diabetic medicines along with this medicine.
- You have type 1 diabetes mellitus.
- You are undergoing any surgery.
- Your doctor tells you that you have increased triglyceride levels in your blood and you have gallstones.
Directions for Use
- Janumet tablet should be taken as directed by your doctor.
- Swallow it as a whole with a glass of water, do not cut, break or chew the medicine.
- It should be taken with meals.
- For optimal results, it would be best to take it at a fixed time and not consume it more than that prescribed by your doctor.
- Do not stop taking Janumet 50mg/500mg tablet on your own without informing your doctor.
Storage and disposal
- Store Janumet tablets at a temperature not above 30°C in a cool and dry place.
- Keep it out of the reach of children and pets.
Quick Tips
- Along with taking Janumet tablet, it is essential that you do certain lifestyle modifications like exercising for 30 minutes daily, maintaining a healthy weight, managing stress, avoiding smoking, and drinking alcohol.
- It is also advised to have a balanced diet with adequate fruits and vegetables to control blood sugar levels effectively.
- Regularly monitor your blood sugar levels as directed by your doctor and report any changes.
- It is essential to take this tablet at the same time every day and not to skip doses. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time.
- Some individuals may experience headache, stomach pain, diarrhoea, and nausea/vomiting after taking the Janumet 50/500mg tablet. Inform your doctor if these effects bother you or do not go away.
- Talk to your doctor if you have kidney or liver disease.
- Take Janumet with your meals for better digestion. Do not cut or break the tablets; swallow them whole. If you have trouble, talk to your doctor.
Dosage
Overdose
Missed a Dose
How does this medicine work?
Interactions
Interactions with other medicines
- Some medicines can affect how Janumet tablet works, or this medicine itself can reduce the effectiveness of other medicines simultaneously.
- Tell your doctor about all the medicines, supplements, or herbs you are taking to avoid any possible interaction.
- Especially if you are taking other antidiabetic medicines.
Interactions with food items
Frequently Asked Questions (FAQs)
References:
- Janumet 50 mg/1000 mg film-coated tablets - Summary of Product Characteristics (SmPC) (emc). Merck Sharp & Dohme. Accessed 31 Jul 2026.
- Janumet 50 mg/1000 mg film-coated tablets - Patient Information Leaflet (PIL) (emc). Merck Sharp & Dohme. Accessed 31 Jul 2026.
- JANUMET (sitagliptin and metformin hydrochloride) tablet - Prescribing Information (USPI). DailyMed, U.S. National Library of Medicine. Accessed 31 Jul 2026.
- Sitagliptin - MedlinePlus Drug Information. U.S. National Library of Medicine. Accessed 31 Jul 2026.
- Metformin - MedlinePlus Drug Information. U.S. National Library of Medicine. Accessed 31 Jul 2026.
- Standards of Care in Diabetes. American Diabetes Association (ADA). Accessed 31 Jul 2026.
- WHO Model List of Essential Medicines. World Health Organization. Accessed 31 Jul 2026.
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Manufacturer Details
Brand:JANUMET
Manufacturer Name:ABBOTT HEALTHCARE PVT LTD
Address:Msd Pharmaceuticals Pvt Ltd., At : M/S Recipharm Pharmaservice Pvt Ltd., Khata No 845/713 And 1108/970/1, 34Th K.M, Tumkur Road,T. Begur, Nelamangala, Bangalore Rural - 562123.
Country of Origin:India
Vendor Details
Fulfillment Information: Janumet 50/500mg Strip Of 15 Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
In Case of Any Issues Contact Us
Email Id:care@pharmeasy.in
Phone Number:7666100300
Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
