Golbi 300mg Strip Of 10 Tablets
By INTAS PHARMACEUTICALS LTD
10 Tablet(s) in Strip
₹484.12
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₹645.50
25% OFF
₹48.41/tablet
(Inclusive of all taxes)
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Offer applicable on order above ₹100015 days return policyRead More
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Description
Golbi Tablet contains ursodeoxycholic acid, a naturally occurring bile acid produced in the liver. This medication is primarily prescribed for treating liver-related disorders, including primary bili
ary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and cholesterol-based gallstones. It is occasionally used to manage liver conditions associated with cystic fibrosis. The mechanism of action of Golbi Tablet involves reducing cholesterol content in bile. Golbi Tablet should be swallowed whole after a meal, accompanied by a glass of milk or water. The dosage will depend on the condition being treated and your body weight. Take it regularly for maximum benefit, for the duration prescribed (several months or longer), even if symptoms disappear. Common side effects may include abdominal pain, diarrhoea, hair loss, itching, nausea, and rash. Not everyone experiences these side effects. If you have concerns or if the side effects persist, inform your doctor. Before taking this medicine, inform your doctor if you have inflammation of the gallbladder or bile ducts, experience frequent cramp-like pain in your upper abdomen, have been coughing up blood, or have gained weight rapidly. Golbi Tablet may affect the effectiveness of other medications, so inform your doctor about all other medications you are taking. Women should discontinue hormonal birth control pills, as they can increase the production of gallstones. Ultrasound scans and frequent blood tests may be necessary to monitor your liver function during treatment.
Product Summary
| Offer Price | ₹484.12 |
| You Save | ₹161.38 (25% on MRP) |
| Contains | Ursodeoxycholic Acid / Ursodiol(300.0 Mg) |
| Uses | Gallbladder stones and Liver dysfunction |
| Side effects | Nausea, vomiting, diarrhoea, sticky stool |
| Therapy | DRUGS FOR CHOLELITHIASIS |
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Uses
- Golbi Tablet is used to dissolve gallbladder stones that are made of cholesterol in various liver-related disorders such as cirrhosis and sclerosing cholangitis.
- Liver dysfunction is associated with cystic fibrosis (a hereditary disease that affects the lungs and digestive system).
Contraindications
- If you are allergic to ursodeoxycholic acid or any ingredient of Golbi Tablet.
- If you have stomach or intestinal ulcer or bleeding.
- If you have recently had surgery involving any part of your intestine.
- If you have a liver-related disorder and non-functional gall bladder.
- If you are suffering from a liver or intestinal condition which affects the circulation of bile substances like blockage of the bile duct.
- If you are suffering from inflammation/blockage of the gall bladder or biliary tract.
Side effects
- Nausea
- Vomiting
- Diarrhoea
- Sticky stool
Precautions and Warnings
Pregnancy
Q:
Can I take Golbi Tablets during pregnancy?
A:
There is limited information on the safety of Golbi Tablets in pregnancy. Hence, it is recommended not to use the same unless prescribed by your doctor.
Breast Feeding
Q:
Can I take Golbi Tablets while breastfeeding?
A:
The safety of Golbi Tablets is not established in breastfeeding women. Hence, it should not be used while breastfeeding.
Driving
Q:
Can I drive if I have consumed Golbi Tablets?
A:
It is not expected that Golbi Tablet will affect your ability to drive but if you do not feel well or are unable to be alert, you should avoid driving.
Alcohol
Q:
Can I consume alcohol with Golbi Tablets?
A:
Although there is no known interaction with alcohol and Golbi Tablet, it is essential to consult your physician if you have a habit of regular drinking.
Other General Warnings
Talk to your doctor if
- You have a history of liver disease or obstruction in bile passage, your doctor may ask you to do a liver function test regularly.
- You experience a persistent diarrhoea, your doctor may discontinue the therapy immediately.
- Women of childbearing age should use non-hormonal contraceptive measures (physical barrier) or low oestrogen oral contraceptive pills. Combination oral contraceptive pills should not be taken with Golbi....
- Your doctor may ask you for an ultrasound after six months of the treatment to check the therapeutic improvement.
- It would be best if you avoided a high cholesterol diet during the treatment as it may affect the effectiveness of Golbi.
Mode of Action
How Does It Work?
Golbi Tablet improve liver function. It works as a dissolving agent and thus reduces the cholesterol content in bile and controls the blood's amount of cholesterol. It is also known to control the synthesis of cholesterol and absorption from the intestine....
Directions for Use
- Golbi Tablet should be taken as directed by your doctor. Swallow it whole with a glass of water. Do not cut, break or chew the medicine.
- It should be taken after having your meal. It would be best if you took it at a fixed time for optimal results.
- You should not consume it more than that prescribed by your doctor.
Interactions
Interactions with other medicines
- Golbi Tablet may interact with other medications and provide an altered response to the treatment. Please notify your doctor if you are undergoing any other treatments, over-the-counter medications (that you buy without a prescription) and herbal preparations. Also, you should inform your doctor if you have a planned surgery or vaccination scheduled....
- Hormonal pills should not be used if you are on treatment with Golbi Tablets.
- Concomitant use of cholesterol-lowering medicines like cholestyramine or colestipol and some antacids may reduce the efficacy of Golbi. So, it should be taken between the gap of 2 hours at least.
- Other medicines that may affect this tablet's absorption are charcoal and antibiotics like Ciprofloxacin, immunosuppressants like Ciclosporin, cholesterol-lowering medicines like Atorvastatin and Dapsone used as an anti-infective. Hence, it should not be used concomitantly....
Interactions with food items
Your doctor may preferably ask you to take Golbi Tablet after meals.
Storage and disposal
- Store Golbi Tablets in a cool and dry place, protected from direct sunlight, moisture and heat.
- Keep it away from children and pets.
- Discard any unused and expired medicine properly. Do not flush in the toilet or throw it into the drain.
Dosage
Overdose
The most common symptom of an overdose of Golbi is diarrhoea. Consult your doctor immediately if you have taken an excessive dose of this medicine.
Missed a Dose
If you missed any dose of Golbi Tablets, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of this medicine to compensate for the missed one....
Content Details
WRITTEN BY
Dr. Mansi Savla
B. Pharm, PharmD
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Can Golbi reduce raised liver enzymes?
A: No, it does not have an action against reducing increased liver enzymes.
Q: Does high blood cholesterol level cause gallbladder stones?
A: High blood cholesterol levels can cause supersaturation of cholesterol crystals, which may eventually lead to gallstone formation.
Q: What is Golbi Tablet used for?
- Golbi Tablet is used to dissolve gallbladder stones that are made of cholesterol in various liver-related disorders such as cirrhosis and sclerosing cholangitis.
- It is also used in liver dysfunction associated with cystic fibrosis (a hereditary disease that affects the lungs and digestive system).
References
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- DESTOLIT 150 mg tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 9 May 2022]
- CDSCO - Ursodeoxycholic acid [Internet]. Cdscoonline.gov.in. 2022 [cited 9 May 2022]
- URSO (ursodiol) tablets, for oral use, USP, [Internet]. Accessdata.fda.gov. 2022 [cited 9 May 2022]
- Lactmed - Ursodiol [Internet]. Ncbi.nlm.nih.gov. 2022 [cited 9 May 2022]
- DESTOLIT 150 mg tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 9 May 2022]
- Information H, Diseases D, Eating &, Eating &, Health N. Eating, Diet, & Nutrition for Gallstones | NIDDK [Internet]. National Institute of Diabetes and Digestive and Kidney Diseases. 2021 [cited 25 October 2021]
- Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis Ovadia, Caroline et al. The Lancet Gastroenterology & Hepatology, Volume 6, Issue 7, 547 - 558
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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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