Glycomet GP 2 Tablet

• If you are allergic to metformin, glimepiride or any of the ingredients of Glycomet-GP 2 tablet.
• If you are pregnant or breastfeeding.
• If you have serious kidney failure or liver failure.
• If you have any metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma.
• If you have dehydration, severe infections, shock and injections containing iodine.
• If you have had heart or lung failure, a recent incidence of heart attack and shock.
• If you are an alcoholic.

• Headache
• Nausea
• Vomiting
• Diarrhoea
• Stomach pain

Other General Warnings

• You experience extreme hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness, confusion, shakiness or dizziness. These could be signs of low blood sugar. If you have any of these, immediately have sugar or sweet juice. Inform your doctor that you may need a change in your medicine dose.
• You are experiencing pins-and-needles sensation, numbness and weakness.
• You will have a diagnostic imaging test involving an injection of iodine.
• You have dehydration due to diarrhoea, vomiting or limited fluid intake.
• You have suffered through trauma.
• You have to undergo surgery in the near future.
• You have serious kidney and liver problems.
• You have a thyroid disorder.
• You are overweight (specific diet restriction may be suggested).

• Glycomet-GP 2 tablet should be taken as directed by your doctor.
• It should be consumed as a whole without chewing or crushing, with a sufficient amount of water and food.
• It would be best if you took it at a fixed time for optimal results.
• You should not consume more than that prescribed by your doctor.

• Store Glycomet-GP 2 tablet at room temperature in a dry place protected from moisture.
• Keep out of the reach of children.

• Glycomet GP 2 tablet is an anti-diabetic medicine. It is used for the management of type 2 diabetes mellitus.
• Take this medicine in the exact dose and duration as recommended by your doctor.
• Along with taking Glycomet GP 2, it is important that you do certain lifestyle modifications like exercising regularly, avoiding smoking and drinking alcohol.
• It is also advised to have a balanced diet with adequate fruits and vegetables for adequate control of your blood sugar levels.
• Low blood glucose levels, flatulence, metallic taste, or diarrhoea may occur in some individuals with the use of this medicine. Inform your doctor if these effects bother you or do not go away.
• Before starting Glycomet GP 2 tablet, inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.
• Glycomet GP 2 tablet should be taken as directed by your doctor. You should not consume more than that prescribed by your doctor.
• Talk to your doctor if you have kidney or liver disease.

Overdose

• Overdose of Glycomet-GP 2 tablet may lead to severe hypoglycemia and lactic acidosis (Excessive lactic acid build-up) & (low blood sugar).
• This can result in headaches, nausea, vomiting, sleep disturbances, restlessness, impaired alertness and reactions, depression, confusion, dizziness, etc.
• If you experience these, immediately take glucose or juice or sugar-containing products (Sugar candy).
• Contact your doctor immediately or visit the nearest hospital as you may require close monitoring for the next few hours.

Missed a Dose

• A missed dose may lead to high blood sugar levels, which includes symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, a fruity smell from breath, etc.
• If you missed any dose of Glycomet-GP 2 tablet, take it as soon as you remember it.
• If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule.
• Do not take a double dose of medicine to compensate for the missed one.

How Does It Work?

• This combination is known to control blood sugar to a greater extent than metformin or glimepiride alone. Glimepiride lowers the blood sugar level increasing release of insulin hormone from the pancreas.
• Insulin moves sugar (glucose) from the blood into the cells.
• Metformin decreases the absorption in the intestine and the production of sugar by the liver.
• Both of these components are known to increase the insulin sensitivity of the body (allows the cells of the body to use blood glucose more effectively, reducing blood sugar).

Interactions with other medicines

• You may have symptoms of low blood sugar if you are taking other medicines for diabetes like Insulin, Pioglitazone, medicines for high blood pressure (ACE inhibitors like Captopril), Steroids, Chloramphenicol, Fenfluramine, Fenyramidol, medicines to lower blood cholesterol (fibrates), medicine to treat depression (Fluoxetine), medicine to treat blood clotting like Coumarins, Cyclophosphamide, Miconazole, Probenecid, antibiotics like Clarithromycin, Doxycycline, Ofloxacin, etc.
• You may have symptoms of high blood sugar if you are taking oral contraceptives, Acetazolamide, Water pills, Phenytoin, Rifampicin, medicines for constipation and medicines for thyroid disorders.
• Medicines like anti-allergic (ranitidine), clonidine, reserpine and medicines used to treat high blood pressure like atenolol can alter the way this medicine works and may block your body's response to low blood sugar. This can lead to dangerously low levels of blood sugar.
• Medicines like Diclofenac, Ibuprofen, Water pill, and Enalapril may affect your kidney functions if taken along with this medicine.
• Medicines used to treat thyroid can affect the way this medicine works.