Dotin 50mg Tablet

• As per CDSCO, Dotin tablet is used for:
• Treatment of depression.
• Treatment of major depressive disorders, such as psychotic depression (severe depressive illness includes some form of psychosis such as hallucinations, delusions, etc.), neurotic depression (neurotic depression is a depression in an emotionally unstable person).
• Treatment of depression unresponsive to other antidepressants.
• Management of anxiety disorder.
• Managing some types of nerve pain, such as fibromyalgia, and to prevent migraines.

• If you have a known allergic reaction to any of its components.
• If you are already using other antidepressants or antipsychotics. It can cause hallucinations, seizures, and different life-threatening side effects.
• If you have any serious heart condition, like a heart attack, irregular heart rhythm
• If you have a rare blood-related illness known as porphyria.
• If you have previously been diagnosed with bipolar disorder or mania
• If you have severe liver impairment
• If you are currently expecting or planning for a pregnancy.
• If you are breastfeeding.
• If you have closed-angle glaucoma, a severe eye condition
• If you notice any sudden mood changes and self-harming or suicidal thoughts.
• Note - Dotin tablets are not recommended for children and adolescents younger than 18 years.

• Increased heart rate
• Weight gain
• Blurred vision
• Sudden fall in blood pressure
• Shaking of arms and feet
• Low sex desire
• Dry mouth

Other General Warnings

• Your blood pressure suddenly drops. Dotin tablets can lower blood pressure when you suddenly change your position.
• You have prostate gland disorder. Dotin tablets can worsen the condition.
• You are using other herbal medicines and supplements.
• You are an older adult; this medicine’s effects can last longer. The dose should be monitored.
• You have any surgery or dental procedure planned.
• You have any kidney or liver condition; dose adjustment might be needed.

• Take the Dotin tablet exactly as prescribed by the doctor.
• Do not change the dose of Dotin tablet, even if you do not see its effects.
• Do not try to break this tablet or chew it and the pill as a whole with a glass of water.
• It is better to not take it with other medications without informing your doctor.
• Do not use Dotin medicine if its packaging has been already opened.
• Do not suddenly stop taking the Dotin tablet, as it can cause adverse effects from withdrawal.
• You can take Dotin medication with or without consuming food.

Overdose

Missed a Dose

How Does It Work?

Interactions with other medicines

• Do not use Dotin Tablet if you are already using other antidepressants like MAO inhibitors such as linezolid, methylene blue and phenelzine, as they can lead to severe side effects like tremors, severe seizures, etc. It can sometimes even lead to death. At least a 14-day gap should be between taking these two medications.
• Do not take other antidepressants with a similar composition like amitriptyline, imipramine, etc. They can exaggerate the side effects of Dotin medicine.
• Do not use Dotin tablets with other medicines that cause sedation and drowsiness, like tranquillisers, opioid or narcotic pain relievers and muscle relaxants, without consulting a doctor.
• If you use antibiotics, antifungal, migraine medicines, Dotin tablets can decrease their effects.
• Dotin tablets can have interactions and side effects with stomach ulcers, antimalarial medicines, heart medicines, and blood thinners.

Interactions with food items

• Try to avoid drinking grapefruit juice and cranberry juice, or eating those fruits, while you are taking Dotin Tablets, as they can increase the levels of this medicine in your blood. It can lead to unwanted adverse effects.