Q: Is this medicine addictive?
A: No, this medicine is not addictive but it is advised not to give this medicine if anyone else has the same condition like you.
Q: What are COX inhibitors? Is Bestofen Tablet a COX inhibitor?
A: COX or cyclooxygenase inhibitors block the enzyme cyclooxygenase which secretes substances in injury or illness that promote pain and inflammation. There are 2 forms of this enzyme called COX-1 and COX-2. While some medicines selectively inhibit COX-1 (Aspirin, Indomethacin) or COX-2 (Etoricoxib, Valdecoxib), Bestofen Tablet inhibits both the enzymes. Bestofen Tablet may increase the intensity of adverse effects when used in combination with other COX inhibitors and hence caution is advised.
Q: Is there anything else I need to know before taking Bestofen Tablet?
A: There should be a minimum 6-hour gap between 2 tablets of Bestofen Tablet and you should not take more than 3 tablets in 24 hours. It is not recommended to use this medicine for more than 4 days on self-prescription. If you have use for a longer period, consult your doctor. This medicine should not be used in children below 12 years of age and who weigh less than 40 kg. (if >12 yrs old).
Q: Why do pain killers cause gastrointestinal bleeding?
A: Pain killers (NSAIDs) irritate or damage the lining of the stomach which results in stomach bleeding. This lead to formation of ulcers or in perforation. However, this does not occur in normal doses and is especially a concern if you are taking pain killers for a prolonged period or use them more than regularly. The risk of gastrointestinal bleeding, ulcers and perforation is higher with higher doses.