Rasagiline

Molecule Description

Rasagiline is used to treat Parkinson’s disease (nervous system disorder that a

ffects movement).

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Rasagiline

To treat the symptoms of Parkinson’s disease (stiffness/ rigidity, tremors, spasms, poor muscle control) as initial monotherapy and as an addition to Levodopa.

Contraindications of Rasagiline

When should one not use Rasagiline

Do not take this medicine if you are allergic to it or have a severe liver problem.

Side effects of Rasagiline

Common side effects of this drug are:

Involuntary movements (dyskinesia)
Headache
Hallucinations (the sight of those objects or people who do not exist in reality), fever, restlessness, tremor and sweating
Constipation, diarrhea, excessive sleepiness, dry mouth
Headache, joint pain, mild stomach pain
Loss of appetite, weight loss
Urinary urgency
Irritation of the skin (dermatitis)
Depression
Runny nose (rhinitis), irritation of the skin (dermatitis)
Rash, bloodshot eyes (conjunctivitis)

Precautions and Warnings of Rasagiline

Pregnancy

Can I take Rasagiline during pregnancy?

The effect of Rasagiline on the fetus is not known, consult your doctor if you are pregnant, your doctor will tell you on the use of this medicine after assessing the benefits over risks.

Breast Feeding

Can I take Rasagiline while breastfeeding?

Tell your doctor if you are breastfeeding, as no information is available on the use of Rasagiline if you are breastfeeding. Your doctor will tell you about the use of this medicine after assessing the benefits over risks.

Driving

Can I drive if I have consumed Rasagiline?

It is not advised to drive any vehicle or use heavy machinery when on this medication.

Alcohol

Can I consume alcohol with Rasagiline?

It is not advised to consume alcohol.

Other General Warnings

Talk to your doctor if

You have liver problems
You notice any changes in your skin while on medication of Rasagiline
Your family and friends notice any changes in your mood and behaviour like compulsions, obsessive thoughts, addictive gambling, excessive spending, impulsive behaviour and an abnormally high sex drive

Mode of Action of Rasagiline

How Does It Work?

In patients of Parkinson’s disease, there is a reduction in the levels of certain chemical neurotransmitters which affect the movement of the body. Rasagiline works by increasing the level of these ch...

Interactions of Rasagiline

Interactions with other medicines

Antidepressants
Antibiotic like Ciprofloxacin
Cough suppressant like Dextromethorphan
Nasal and oral decongestants and cold medicine like Ephedrine or Pseudoephedrine

Interactions with food items

Avoid tyramine containing products like aged cheese, aged, dried, fermented, salted, smoked, pickled and processed meats and fish, concentrated yeast extracts, packaged soups
Do not take caffeine, chocolates, coffee or cola with this medicine

Dietary Restrictions of Rasagiline

Avoid the following tyramine containing products-
Aged cheese
Packaged soups
Caffeine
Chocolates
Coffee
Cola

Dosage of Rasagiline

Overdose

If you overdose with Rasagiline, immediately call your doctor or visit the nearest hospital. Signs and symptoms of Rasagiline overdose may include brain-related issues like sleepiness, unsteadiness, f...

Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose if it is too late. Do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking this medicine?

A: Give a detailed account of your medical and surgical history. Also, notify your doctor about all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.

Q: What special precautions should I take while on this medication?

Use Rasagiline with caution if you have high blood pressure because it may worsen the condition
Avoid the following tyramine containing products-
Aged cheese
Aged, dried, fermented, salted, smoked, pickled and processed meats and fish
Commercial gravies
Concentrated yeast extracts
Packaged soups
Do not take caffeine, chocolates, coffee or cola with this medicine

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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